Sridhar Sivasubbu CSIR-Institute of Genomics and Integrative Biology Biography Publications Institution JoVE Articles Sridhar Sivasubbu has not added a biography. If you are Sridhar Sivasubbu and would like to personalize this page please email our Author Liaison for assistance. Publications An Insertion Map of the Indian Population: Identification and Analysis in 1021 Genomes of the IndiGen Project NAR Genomics and Bioinformatics. Mar, 2022 | Pubmed ID: 35178516 Clinical, Immunological and Genomic Characteristics of Children with X-linked Agammaglobulinemia from Kerala, South India Human Immunology. Jan, 2022 | Pubmed ID: 35074268 Variants of Concern Responsible for SARS-CoV-2 Vaccine Breakthrough Infections from India Journal of Medical Virology. 04, 2022 | Pubmed ID: 34786733 Genetic Epidemiology of Autoinflammatory Disease Variants in Indian Population from 1029 Whole Genomes Journal, Genetic Engineering & Biotechnology. Dec, 2021 | Pubmed ID: 34905135 SARS-CoV-2 Vaccine Breakthrough Infection Following a Previous Infection in a Healthcare Worker The Journal of Infection. Oct, 2021 | Pubmed ID: 34678389 Genomic Characterization and Epidemiology of an Emerging SARS-CoV-2 Variant in Delhi, India Science (New York, N.Y.). 11, 2021 | Pubmed ID: 34648303 A Genome-wide Circular RNA Transcriptome in Rat Biology Methods & Protocols. 2021 | Pubmed ID: 34527809 An Optimized, Amplicon-based Approach for Sequencing of SARS-CoV-2 from Patient Samples Using COVIDSeq Assay on Illumina MiSeq Sequencing Platforms STAR Protocols. 09, 2021 | Pubmed ID: 34368787 Whole Genome Sequencing Identifies Novel Structural Variant in a Large Indian Family Affected with X-linked Agammaglobulinemia PloS One. 2021 | Pubmed ID: 34252140 LncRNA VEAL2 Regulates PRKCB2 to Modulate Endothelial Permeability in Diabetic Retinopathy The EMBO Journal. 08, 2021 | Pubmed ID: 34180064 Genomic Survey of SARS-CoV-2 Vaccine Breakthrough Infections in Healthcare Workers from Kerala, India The Journal of Infection. 08, 2021 | Pubmed ID: 34044037 Genome and Transcriptome Analysis of the Mealybug Maconellicoccus Hirsutus: Correlation with Its Unique Phenotypes Genomics. 07, 2021 | Pubmed ID: 34022346 Symptomatic Reinfection of SARS-CoV-2 with Spike Protein Variant N440K Associated with Immune Escape Journal of Medical Virology. 07, 2021 | Pubmed ID: 33818797 High Throughput Detection and Genetic Epidemiology of SARS-CoV-2 Using COVIDSeq Next-generation Sequencing PloS One. 2021 | Pubmed ID: 33596239 Chronic Systemic Exposure to IL6 Leads to Deregulation of Glycolysis and Fat Accumulation in the Zebrafish Liver Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 05, 2021 | Pubmed ID: 33582286 Genomic Analysis of Patients in a South Indian Community with Autosomal Dominant Cortical Tremor, Myoclonus and Epilepsy Suggests a Founder Repeat Expansion Mutation in the Gene Brain Communications. 2021 | Pubmed ID: 33501421 DALIA- a Comprehensive Resource of Disease Alleles in Arab Population PloS One. 2021 | Pubmed ID: 33439861 Asymptomatic Reactivation of SARS-CoV-2 in a Child with Neuroblastoma Characterised by Whole Genome Sequencing IDCases. 2021 | Pubmed ID: 33288996 Analysis of the Potential Impact of Genomic Variants in Global SARS-CoV-2 Genomes on Molecular Diagnostic Assays International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Jan, 2021 | Pubmed ID: 33181329 IndiGenomes: a Comprehensive Resource of Genetic Variants from over 1000 Indian Genomes Nucleic Acids Research. 01, 2021 | Pubmed ID: 33095885 Parental Experience of Hematopoietic Stem Cell Transplantation for Children with Primary Immune Deficiency Disorders Indian Journal of Pediatrics. 04, 2021 | Pubmed ID: 33095397 Asymptomatic Reinfection in 2 Healthcare Workers From India With Genetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 11, 2021 | Pubmed ID: 32964927 A Rapid and Sensitive Method to Detect SARS-CoV-2 Virus Using Targeted-mass Spectrometry Journal of Proteins and Proteomics. 2020 | Pubmed ID: 33132628 Spectrum of Clinical Features and Genetic Variants in Mevalonate Kinase (MVK) Gene of South Indian Families Suffering from Hyperimmunoglobulin D Syndrome PloS One. 2020 | Pubmed ID: 32822427 Building the Vertebrate Codex Using the Gene Breaking Protein Trap Library ELife. 08, 2020 | Pubmed ID: 32779569 Maternal Vitamin B Deficiency in Rats Alters DNA Methylation in Metabolically Important Genes in Their Offspring Molecular and Cellular Biochemistry. May, 2020 | Pubmed ID: 32189172 Histone Variant Dictates Fate Biasing of Neural Crest Cells to Melanocyte Lineage Development (Cambridge, England). 03, 2020 | Pubmed ID: 32098766 Role of Tmem163 in Zinc-regulated Insulin Storage of MIN6 Cells: Functional Exploration of an Indian Type 2 Diabetes GWAS Associated Gene Biochemical and Biophysical Research Communications. 02, 2020 | Pubmed ID: 31813547 A Temporal Map of Gene Expression Pattern During Zebrafish Liver Regeneration Zebrafish. 02, 2020 | Pubmed ID: 31770088 PH-controlled Histone Acetylation Amplifies Melanocyte Differentiation Downstream of MITF EMBO Reports. 01, 2020 | Pubmed ID: 31709752 Saliva Microbiome in Primary Sjögren's Syndrome Reveals Distinct Set of Disease-associated Microbes Oral Diseases. Mar, 2020 | Pubmed ID: 31514257 Genomics of Rare Genetic Diseases-experiences from India Human Genomics. 09, 2019 | Pubmed ID: 31554517 Investigating Coronary Artery Disease Methylome Through Targeted Bisulfite Sequencing Gene. Dec, 2019 | Pubmed ID: 31499127 Loss of Function Mutation in the P2X7, a Ligand-gated Ion Channel Gene Associated with Hypertrophic Cardiomyopathy Purinergic Signalling. 06, 2019 | Pubmed ID: 31152337 A Novel Cathepsin D Mutation in 2 Siblings with Late Infantile Neuronal Ceroid Lipofuscinosis Neurology. Genetics. Jun, 2019 | Pubmed ID: 31086824 A Genome-wide Map of Circular RNAs in Adult Zebrafish Scientific Reports. 03, 2019 | Pubmed ID: 30837568 Methods to Study Long Noncoding RNA Expression and Dynamics in Zebrafish Using RNA Sequencing Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30635891 Methods for Annotation and Validation of Circular RNAs from RNAseq Data Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30635890 Knockdown of Calcium-binding Calb2a and Calb2b Genes Indicates the Key Regulator of the Early Development of the Zebrafish, Danio Rerio Brain Structure & Function. Mar, 2019 | Pubmed ID: 30460553 Identification of Novel Circadian Transcripts in the Zebrafish Retina The Journal of Experimental Biology. 01, 2019 | Pubmed ID: 30446534 Organellar Transcriptome Sequencing Reveals Mitochondrial Localization of Nuclear Encoded Transcripts Mitochondrion. 05, 2019 | Pubmed ID: 29486245 Large Scale Changes in the Transcriptome of Eisenia Fetida During Regeneration PloS One. 2018 | Pubmed ID: 30260966 Whole Exome Sequencing in a Multi-generation Family from India Reveals a Genetic Variation C.10C>T (p.Gln4Ter) in Keratin 5 Gene Associated with Dowling-Degos Disease Indian Journal of Dermatology, Venereology and Leprology. May-Jun, 2018 | Pubmed ID: 29600799 RNA Secondary Structure Profiling in Zebrafish Reveals Unique Regulatory Features BMC Genomics. 02, 2018 | Pubmed ID: 29448945 STIM1 Activation of Adenylyl Cyclase 6 Connects Ca and CAMP Signaling During Melanogenesis The EMBO Journal. 03, 2018 | Pubmed ID: 29311116 RNA Sequencing of Db/db Mice Liver Identifies LncRNA H19 As a Key Regulator of Gluconeogenesis and Hepatic Glucose Output Scientific Reports. 08, 2017 | Pubmed ID: 28814771 Classical Autophagy Proteins LC3B and ATG4B Facilitate Melanosome Movement on Cytoskeletal Tracks Autophagy. Aug, 2017 | Pubmed ID: 28598240 Neuroanatomical Demonstration of Calbindin 2a- and Calbindin 2b-like Calcium Binding Proteins in the Early Embryonic Development of Zebrafish: MRNA Study International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Aug, 2017 | Pubmed ID: 28396290 Egyptian Tale from India: Application of Whole-exome Sequencing in Diagnosis of Atypical Familial Mediterranean Fever International Journal of Rheumatic Diseases. Feb, 2017 | Pubmed ID: 28211254 Case Report: Whole Exome Sequencing Identifies Variation C.2308G>A P.E770K in Associated with B- T- NK+ Severe Combined Immunodeficiency F1000Research. 2016 | Pubmed ID: 29067161 Case Report: Application of Whole Exome Sequencing for Accurate Diagnosis of Rare Syndromes of Mineralocorticoid Excess F1000Research. 2016 | Pubmed ID: 29067160 Case Report: Whole Exome Sequencing Identifies a Novel Frameshift Insertion C.1325dupT (p.F442fsX2) in the Tyrosine Kinase Domain of Gene in a Young Indian Individual with X-linked Agammaglobulinemia F1000Research. 2016 | Pubmed ID: 28928935 Case Report: Whole Exome Sequencing Reveals a Novel Frameshift Deletion Mutation P.G2254fs in COL7A1 Associated with Autosomal Recessive Dystrophic Epidermolysis Bullosa F1000Research. 2016 | Pubmed ID: 27408687 Development of a Fluorescent Transgenic Zebrafish Biosensor for Sensing Aquatic Heavy Metal Pollution Transgenic Research. 10, 2016 | Pubmed ID: 27120052 Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding PLoS Genetics. Apr, 2016 | Pubmed ID: 27082250 Aptamer-Assisted Detection of the Altered Expression of Estrogen Receptor Alpha in Human Breast Cancer PloS One. 2016 | Pubmed ID: 27043307 Chamber Specific Gene Expression Landscape of the Zebrafish Heart PloS One. 2016 | Pubmed ID: 26815362 Case Report: Whole Exome Sequencing Helps in Accurate Molecular Diagnosis in Siblings with a Rare Co-occurrence of Paternally Inherited 22q12 Duplication and Autosomal Recessive Non-syndromic Ichthyosis F1000Research. 2015 | Pubmed ID: 26594337 ZflncRNApedia: A Comprehensive Online Resource for Zebrafish Long Non-Coding RNAs PloS One. 2015 | Pubmed ID: 26065909 Screening Currency Notes for Microbial Pathogens and Antibiotic Resistance Genes Using a Shotgun Metagenomic Approach PloS One. 2015 | Pubmed ID: 26035208 Exome Sequencing of Patients with Histiocytoid Cardiomyopathy Reveals a De Novo NDUFB11 Mutation That Plays a Role in the Pathogenesis of Histiocytoid Cardiomyopathy American Journal of Medical Genetics. Part A. Sep, 2015 | Pubmed ID: 25921236 Comparative Whole-genome Analysis of Clinical Isolates Reveals Characteristic Architecture of Mycobacterium Tuberculosis Pangenome PloS One. 2015 | Pubmed ID: 25853708 Erratum for Behera Et Al., Draft Genome Sequence of the Extremely Halophilic Bacterium Halomonas Salina Strain CIFRI1, Isolated from the East Coast of India Genome Announcements. 02, 2015 | Pubmed ID: 25700399 Mit-o-matic: a Comprehensive Computational Pipeline for Clinical Evaluation of Mitochondrial Variations from Next-generation Sequencing Datasets Human Mutation. Apr, 2015 | Pubmed ID: 25677119 Draft Genome Sequence of the Extremely Halophilic Bacterium Halomonas Salina Strain CIFRI1, Isolated from the East Coast of India Genome Announcements. Jan, 2015 | Pubmed ID: 25573926 Exome Sequencing Reveals a Novel Mutation, P.L325H, in the KRT5 Gene Associated with Autosomal Dominant Epidermolysis Bullosa Simplex Koebner Type in a Large Family from Western India Human Genome Variation. 2014 | Pubmed ID: 27081501 Short Stories on Zebrafish Long Noncoding RNAs Zebrafish. Dec, 2014 | Pubmed ID: 25110965 Non-coding RNA Based Regulation of Blood Vessel Development in Zebrafish and Relevance to Humans Molecular Cytogenetics. 2014 | Pubmed ID: 24940357 Human 45,X Fibroblast Transcriptome Reveals Distinct Differentially Expressed Genes Including Long Noncoding RNAs Potentially Associated with the Pathophysiology of Turner Syndrome PloS One. 2014 | Pubmed ID: 24932682 The Zebrafish GenomeWiki: a Crowdsourcing Approach to Connect the Long Tail for Zebrafish Gene Annotation Database : the Journal of Biological Databases and Curation. 2014 | Pubmed ID: 24578356 Draft Genome Sequence of Urease-Producing Sporosarcina Pasteurii with Potential Application in Biocement Production Genome Announcements. Jan, 2014 | Pubmed ID: 24482521 Morphological Effects of G-quadruplex Stabilization Using a Small Molecule in Zebrafish Biochemistry. Feb, 2014 | Pubmed ID: 24476096 Dynamic Expression of Long Non-coding RNAs (lncRNAs) in Adult Zebrafish PloS One. 2013 | Pubmed ID: 24391796 Time for the Zebrafish ENCODE Journal of Genetics. Dec, 2013 | Pubmed ID: 24371190 Draft Genome Sequence of a Multidrug-Resistant Clinical Isolate of Mycobacterium Tuberculosis Belonging to a Novel Spoligotype Genome Announcements. Nov, 2013 | Pubmed ID: 24265496 Draft Genome Sequence of Multidrug-Resistant Mycobacterium Tuberculosis Clinical Isolate OSDD515, Belonging to the Uganda I Genotype Genome Announcements. Nov, 2013 | Pubmed ID: 24265488 Draft Genome Sequence of an Extensively Drug-Resistant Mycobacterium Tuberculosis Clinical Isolate of the Ural Strain OSDD493 Genome Announcements. Nov, 2013 | Pubmed ID: 24201204 Systematic Pharmacogenomics Analysis of a Malay Whole Genome: Proof of Concept for Personalized Medicine PloS One. 2013 | Pubmed ID: 24009664 Draft Genome Sequence of a Clinical Isolate of Multidrug-Resistant Mycobacterium Tuberculosis East African Indian Strain OSDD271 Genome Announcements. Aug, 2013 | Pubmed ID: 23908284 LncRNome: a Comprehensive Knowledgebase of Human Long Noncoding RNAs Database : the Journal of Biological Databases and Curation. 2013 | Pubmed ID: 23846593 A Sequence-based Variation Map of Zebrafish Zebrafish. Mar, 2013 | Pubmed ID: 23590399 MiR-34 is Maternally Inherited in Drosophila Melanogaster and Danio Rerio Nucleic Acids Research. Apr, 2013 | Pubmed ID: 23470996 Systematic Transcriptome Wide Analysis of LncRNA-miRNA Interactions PloS One. 2013 | Pubmed ID: 23405074 Reverse Genetics Screen in Zebrafish Identifies a Role of MiR-142a-3p in Vascular Development and Integrity PloS One. 2012 | Pubmed ID: 23285103 Conceptual Approaches for LncRNA Drug Discovery and Future Strategies Expert Opinion on Drug Discovery. Jun, 2012 | Pubmed ID: 22559214 A Case for Pharmacogenomics in Management of Cardiac Arrhythmias Indian Pacing and Electrophysiology Journal. Mar, 2012 | Pubmed ID: 22557843 High Resolution Methylome Map of Rat Indicates Role of Intragenic DNA Methylation in Identification of Coding Region PloS One. 2012 | Pubmed ID: 22355382 Antagonism of MicroRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes) Chembiochem : a European Journal of Chemical Biology. Mar, 2012 | Pubmed ID: 22315191 从单元格文化 Hologenomes 病毒病原的 De Novo 标识。 BMC Research Notes. Jan, 2012 | Pubmed ID: 22226071 Proteomic Analysis of Zebrafish (Danio Rerio) Embryos Exposed to Cyclosporine A Journal of Proteomics. Jan, 2012 | Pubmed ID: 22079245 使用斑马鱼鉴定色素沉着调节因子的反向遗传方法 Babita Sharma*1,2, Yogaspoorthi J. Subramaniam*1,2, Desingu Ayyappa Raja1,2,3, Ayush Aggarwal1,2, Sridhar Sivasubbu1, Vivek T. Natarajan1,2 1CSIR-Institute of Genomics and Integrative Biology, 2Academy of Scientific and Innovative Research, 3Division of Biology and Biological Engineering, California Institute of Technology JoVE 62955 Biology
使用斑马鱼鉴定色素沉着调节因子的反向遗传方法 Babita Sharma*1,2, Yogaspoorthi J. Subramaniam*1,2, Desingu Ayyappa Raja1,2,3, Ayush Aggarwal1,2, Sridhar Sivasubbu1, Vivek T. Natarajan1,2 1CSIR-Institute of Genomics and Integrative Biology, 2Academy of Scientific and Innovative Research, 3Division of Biology and Biological Engineering, California Institute of Technology JoVE 62955 Biology