Stephanie W. Watts Department of Pharmacology and Toxicology Michigan State University Biography Publications Institution JoVE Articles Stephanie W. Watts has not added a biography. If you are Stephanie W. Watts and would like to personalize this page please email our Author Liaison for assistance. Publications 5-HT Causes Splanchnic Venodilation American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2017 | Pubmed ID: 28626072 Perivascular Adipose Tissue's Impact on Norepinephrine-Induced Contraction of Mesenteric Resistance Arteries Frontiers in Physiology. 2017 | Pubmed ID: 28228728 Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury The Journal of Pharmacology and Experimental Therapeutics. Mar, 2017 | Pubmed ID: 28035008 3T3-L1 Cells and Perivascular Adipocytes Are Not Equivalent in Amine Transporter Expression FEBS Letters. Jan, 2017 | Pubmed ID: 27926779 Chemerin-induced Arterial Contraction is Gi- and Calcium-dependent Vascular Pharmacology. Jan, 2017 | Pubmed ID: 27890480 New Actions of an Old Friend: Perivascular Adipose Tissue's Adrenergic Mechanisms British Journal of Pharmacology. Nov, 2016 | Pubmed ID: 27813085 The Distribution and Adipogenic Potential of Perivascular Adipose Tissue Adipocyte Progenitors is Dependent on Sexual Dimorphism and Vessel Location Physiological Reports. Oct, 2016 | Pubmed ID: 27738018 Oh, the Places You'll Go! My Many Colored Serotonin (apologies to Dr. Seuss) American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2016 | Pubmed ID: 27663771 The Adipokine Chemerin Amplifies Electrical Field-stimulated Contraction in the Isolated Rat Superior Mesenteric Artery American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2016 | Pubmed ID: 27371688 Serial Measurements of Splanchnic Vein Diameters in Rats Using High-Frequency Ultrasound Frontiers in Pharmacology. 2016 | Pubmed ID: 27199758 Pharmacological Research and Precision Cancer Medicine: A Call for Manuscripts Pharmacological Research. Dec, 2015 | Pubmed ID: 26542638 Introducing a Checklist for Manuscript Submission to Pharmacological Research Pharmacological Research. Dec, 2015 | Pubmed ID: 26523875 Organic Cation Transporter 3 Contributes to Norepinephrine Uptake into Perivascular Adipose Tissue American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2015 | Pubmed ID: 26432838 An Immunohistochemical Analysis of SERT in the Blood-brain Barrier of the Male Rat Brain Histochemistry and Cell Biology. Oct, 2015 | Pubmed ID: 26223876 Chemerin: A Comprehensive Review Elucidating the Need for Cardiovascular Research Pharmacological Research. Sep, 2015 | Pubmed ID: 26211950 Trash Talk by Fat: Chemerin As a Reactive Oxygen Species Provocateur in the Vasculature Hypertension (Dallas, Tex. : 1979). Sep, 2015 | Pubmed ID: 26150433 5-Hydroxytryptamine Does Not Reduce Sympathetic Nerve Activity or Neuroeffector Function in the Splanchnic Circulation European Journal of Pharmacology. May, 2015 | Pubmed ID: 25732865 5-HT is a Potent Relaxant in Rat Superior Mesenteric Veins Pharmacology Research & Perspectives. Feb, 2015 | Pubmed ID: 25692021 Transglutaminase Activity is Decreased in Large Arteries from Hypertensive Rats Compared with Normotensive Controls American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2015 | Pubmed ID: 25599570 Tissue Transglutaminase Promotes Serotonin-induced AKT Signaling and Mitogenesis in Pulmonary Vascular Smooth Muscle Cells Cellular Signalling. Dec, 2014 | Pubmed ID: 25218191 Elimination of Vitamin D Receptor in Vascular Endothelial Cells Alters Vascular Function Hypertension. Dec, 2014 | Pubmed ID: 25201890 Serotonin and Sensory Nerves: Meeting in the Cardiovascular System Vascular Pharmacology. Oct, 2014 | Pubmed ID: 25181552 The Persistence of Active Smooth Muscle in the Female Rat Cervix Through Pregnancy American Journal of Obstetrics and Gynecology. Aug, 2014 | Pubmed ID: 25108144 Divergent Signaling Mechanisms for Venous Versus Arterial Contraction As Revealed by Endothelin-1 Journal of Vascular Surgery. Apr, 2014 | Pubmed ID: 24726828 Chemerin Connects Fat to Arterial Contraction Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2013 | Pubmed ID: 23559624 Long-Term Inhibition of Xanthine Oxidase by Febuxostat Does Not Decrease Blood Pressure in Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats PloS One. 2013 | Pubmed ID: 23393607 One-Month Serotonin Infusion Results in a Prolonged Fall in Blood Pressure in the Deoxycorticosterone Acetate (DOCA) Salt Hypertensive Rat ACS Chemical Neuroscience. Jan, 2013 | Pubmed ID: 23336053 Reverse-mode Na+/Ca2+ Exchange is an Important Mediator of Venous Contraction Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Dec, 2012 | Pubmed ID: 22974823 5-hydroxytryptamine (5-HT) Reduces Total Peripheral Resistance During Chronic Infusion: Direct Arterial Mesenteric Relaxation is Not Involved BMC Pharmacology. 2012 | Pubmed ID: 22559843 Serotonin and Blood Pressure Regulation Pharmacological Reviews. Apr, 2012 | Pubmed ID: 22407614 Smooth Muscle Pharmacology in the Isolated Virgin and Pregnant Rat Uterus and Cervix The Journal of Pharmacology and Experimental Therapeutics. Jun, 2012 | Pubmed ID: 22366660 Vena Cava and Aortic Smooth Muscle Cells Express Transglutaminases 1 and 4 in Addition to Transglutaminase 2 American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2012 | Pubmed ID: 22307675 Drug Delivery: Enabling Technology for Drug Discovery and Development. IPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable Frontiers in Pharmacology. 2011 | Pubmed ID: 21863140 Indoleamine 2,3-diooxygenase in Periaortic Fat: Mechanisms of Inhibition of Contraction American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2011 | Pubmed ID: 21841011 Lack of the Serotonin Transporter (SERT) Reduces the Ability of 5-hydroxytryptamine to Lower Blood Pressure Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2011 | Pubmed ID: 21448568 Characterization of Vabicaserin (SCA-136), a Selective 5-hydroxytryptamine 2C Receptor Agonist The Journal of Pharmacology and Experimental Therapeutics. Jun, 2011 | Pubmed ID: 21402690 Comparison of the Function of the Serotonin Transporter in the Vasculature of Male and Female Rats Clinical and Experimental Pharmacology & Physiology. May, 2011 | Pubmed ID: 21371073 Serotonin Transporter Interacts with the PDGFβ Receptor in PDGF-BB-induced Signaling and Mitogenesis in Pulmonary Artery Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2011 | Pubmed ID: 21186266 5-hydroxtryptamine Receptors in Systemic Hypertension: an Arterial Focus Cardiovascular Therapeutics. Feb, 2011 | Pubmed ID: 20433685 Modification of Proteins by Norepinephrine is Important for Vascular Contraction Frontiers in Physiology. 2010 | Pubmed ID: 21423373 Allopurinol Does Not Decrease Blood Pressure or Prevent the Development of Hypertension in the Deoxycorticosterone Acetate-salt Rat Model Journal of Cardiovascular Pharmacology. Dec, 2010 | Pubmed ID: 20881613 The Interdependence of Endothelin-1 and Calcium: a Review Clinical Science (London, England : 1979). Nov, 2010 | Pubmed ID: 20662769 Serotonin Receptors in Rat Jugular Vein: Presence and Involvement in the Contraction The Journal of Pharmacology and Experimental Therapeutics. Jul, 2010 | Pubmed ID: 20378714 Whole Grape Intake Impacts Cardiac Peroxisome Proliferator-activated Receptor and Nuclear Factor KappaB Activity and Cytokine Expression in Rats with Diastolic Dysfunction Hypertension. May, 2010 | Pubmed ID: 20231522 Uric Acid Does Not Affect the Acetylcholine-induced Relaxation of Aorta from Normotensive and Deoxycorticosterone Acetate-salt Hypertensive Rats The Journal of Pharmacology and Experimental Therapeutics. Jun, 2010 | Pubmed ID: 20215410 Endothelin Receptors: What's New and What Do We Need to Know? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2010 | Pubmed ID: 19907001 Differential Expression of Pancreatitis-associated Protein and Thrombospondins in Arterial Versus Venous Tissues Journal of Vascular Research. 2009 | Pubmed ID: 19571575 Serotonylation of Vascular Proteins Important to Contraction PloS One. 2009 | Pubmed ID: 19479059 Endothelin ET(B) Receptors in Arteries and Veins: Multiple Actions in the Vein The Journal of Pharmacology and Experimental Therapeutics. Jun, 2009 | Pubmed ID: 19297422 Body Distribution of Infused Serotonin in Rats Clinical and Experimental Pharmacology & Physiology. May, 2009 | Pubmed ID: 19207716 The Love of a Lifetime: 5-HT in the Cardiovascular System American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2009 | Pubmed ID: 18753260 The Beginning of a Fantastic, Unanswered Question: is 5-HT Involved in Systemic Hypertension? American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2008 | Pubmed ID: 18775854 A Comparison of Reactive Oxygen Species Metabolism in the Rat Aorta and Vena Cava: Focus on Xanthine Oxidase American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2008 | Pubmed ID: 18660442 Lack of the Serotonin Transporter Does Not Prevent Mineralocorticoid Hypertension in Rat and Mouse European Journal of Pharmacology. Jul, 2008 | Pubmed ID: 18573249 Pharmacological Endothelin Receptor Interaction Does Not Occur in Veins from ET(B) Receptor Deficient Rats Vascular Pharmacology. Jul, 2008 | Pubmed ID: 18485831 A Serotonergic System in Veins: Serotonin Transporter-independent Uptake The Journal of Pharmacology and Experimental Therapeutics. Jun, 2008 | Pubmed ID: 18322152 5-Hydroxytryptamine Lowers Blood Pressure in Normotensive and Hypertensive Rats The Journal of Pharmacology and Experimental Therapeutics. Jun, 2008 | Pubmed ID: 18305011 Role of Redox Signaling and Poly (adenosine Diphosphate-ribose) Polymerase Activation in Vascular Smooth Muscle Cell Growth Inhibition by Nitric Oxide and Peroxynitrite Journal of Vascular Surgery. Mar, 2008 | Pubmed ID: 18295111 Vascular Reactivity, 5-HT Uptake, and Blood Pressure in the Serotonin Transporter Knockout Rat American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2008 | Pubmed ID: 18263707 Big ET-1 Processing into Vasoactive Peptides in Arteries and Veins Vascular Pharmacology. Nov-Dec, 2007 | Pubmed ID: 17904426 The Cytochrome P450 Inhibitor Ketoconazole Potentiates 5-hydroxytryptamine-induced Contraction in Rat Aorta The Journal of Pharmacology and Experimental Therapeutics. Nov, 2007 | Pubmed ID: 17687070 Serotonin (5-HT) in Veins: Not All in Vain The Journal of Pharmacology and Experimental Therapeutics. Nov, 2007 | Pubmed ID: 17671100 Methyl-beta-cyclodextrin Prevents Angiotensin II-induced Tachyphylactic Contractile Responses in Rat Aorta The Journal of Pharmacology and Experimental Therapeutics. Oct, 2007 | Pubmed ID: 17636007 Preferential Myosin Heavy Chain Isoform B Expression May Contribute to the Faster Velocity of Contraction in Veins Versus Arteries Journal of Vascular Research. 2007 | Pubmed ID: 17377397 The 5-hydroxytryptamine2A Receptor is Involved in (+)-norfenfluramine-induced Arterial Contraction and Blood Pressure Increase in Deoxycorticosterone Acetate-salt Hypertension The Journal of Pharmacology and Experimental Therapeutics. May, 2007 | Pubmed ID: 17289838 Morphological and Biochemical Characterization of Remodeling in Aorta and Vena Cava of DOCA-salt Hypertensive Rats American Journal of Physiology. Heart and Circulatory Physiology. May, 2007 | Pubmed ID: 17237246 A Comparison of Arteries and Veins in Oxidative Stress: Producers, Destroyers, Function, and Disease Experimental Biology and Medicine (Maywood, N.J.). Jan, 2007 | Pubmed ID: 17202583 Cyclooxygenase, P38 Mitogen-activated Protein Kinase (MAPK), Extracellular Signal-regulated Kinase MAPK, Rho Kinase, and Src Mediate Hydrogen Peroxide-induced Contraction of Rat Thoracic Aorta and Vena Cava The Journal of Pharmacology and Experimental Therapeutics. Jan, 2007 | Pubmed ID: 17003231 A New Signaling Paradigm for Serotonin: Use of Crk-associated Substrate in Arterial Contraction American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2006 | Pubmed ID: 16861698 Mechanisms of Hypertension Induced by Nitric Oxide (NO) Deficiency: Focus on Venous Function Journal of Cardiovascular Pharmacology. Jun, 2006 | Pubmed ID: 16810074 5-hydroxytryptamine in the Cardiovascular System: Focus on the Serotonin Transporter (SERT) Clinical and Experimental Pharmacology & Physiology. Jul, 2006 | Pubmed ID: 16789923 Arterial 5-hydroxytryptamine Transporter Function is Impaired in Deoxycorticosterone Acetate and Nomega-nitro-L-arginine but Not Spontaneously Hypertensive Rats Hypertension. Jul, 2006 | Pubmed ID: 16754787 Pleiotropic Effects of Hydrogen Peroxide in Arteries and Veins from Normotensive and Hypertensive Rats Hypertension. Mar, 2006 | Pubmed ID: 16432037 Vasoconstriction Caused by the ATP Synthase Subunit-coupling Factor 6: a New Function for a Historical Enzyme Hypertension. Nov, 2005 | Pubmed ID: 16230522 Activation of Vascular BK Channel by Tempol in DOCA-salt Hypertensive Rats Hypertension. Nov, 2005 | Pubmed ID: 16216988 Upregulated Function of Phosphatidylinositol-3-kinase in Genetically Hypertensive Rats: a Moderator of Arterial Hypercontractility Clinical and Experimental Pharmacology & Physiology. Oct, 2005 | Pubmed ID: 16173947 Endothelin-1-induced Contraction in Veins is Independent of Hydrogen Peroxide American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2005 | Pubmed ID: 15908460 (+)-Norfenfluramine-induced Arterial Contraction is Not Dependent on Endogenous 5-hydroxytryptamine or 5-hydroxytryptamine Transporter The Journal of Pharmacology and Experimental Therapeutics. Sep, 2005 | Pubmed ID: 15901794 5-HT in Systemic Hypertension: Foe, Friend or Fantasy? Clinical Science (London, England : 1979). May, 2005 | Pubmed ID: 15831089 Preserving and Promoting Our Discipline: Pharmacology Students Speak Out Molecular Interventions. Feb, 2005 | Pubmed ID: 15731498 Endothelin in the Splanchnic Vascular Bed of DOCA-salt Hypertensive Rats American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2005 | Pubmed ID: 15471983 Effects of PPAR-gamma Ligands on Vascular Smooth Muscle Marker Expression in Hypertensive and Normal Arteries American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2005 | Pubmed ID: 15345487 The Serotonin Transporter is Present and Functional in Peripheral Arterial Smooth Muscle Journal of Cardiovascular Pharmacology. Jun, 2004 | Pubmed ID: 15167270 C3 or Not C3: That is the Question Hypertension. Jul, 2004 | Pubmed ID: 15123574 Increased Vascular Sensitivity and Connexin43 Expression After Sympathetic Denervation Cardiovascular Research. May, 2004 | Pubmed ID: 15094358 Arteries and Veins Desensitize Differently to Endothelin Journal of Cardiovascular Pharmacology. Mar, 2004 | Pubmed ID: 15076222 Increased O2*- Production and Upregulation of ETB Receptors by Sympathetic Neurons in DOCA-salt Hypertensive Rats Hypertension. May, 2004 | Pubmed ID: 15051669 PI3-kinase Upregulation and Involvement in Spontaneous Tone in Arteries from DOCA-salt Rats: is P110delta the Culprit? Hypertension. Apr, 2004 | Pubmed ID: 14993194 Rho/Rho Kinase and Phosphoinositide 3-kinase Are Parallel Pathways in the Development of Spontaneous Arterial Tone in Deoxycorticosterone Acetate-salt Hypertension The Journal of Pharmacology and Experimental Therapeutics. Jun, 2004 | Pubmed ID: 14982964 The Fenfluramine Metabolite (+)-norfenfluramine is Vasoactive The Journal of Pharmacology and Experimental Therapeutics. May, 2004 | Pubmed ID: 14752059 Characterization of the Contractile 5-hydroxytryptamine Receptor in the Renal Artery of the Normotensive Rat The Journal of Pharmacology and Experimental Therapeutics. Apr, 2004 | Pubmed ID: 14724222 Low [Mg2+]e Enhances Arterial Spontaneous Tone Via Phosphatidylinositol 3-kinase in DOCA-salt Hypertension Hypertension. Jan, 2004 | Pubmed ID: 14638620 Arterial Expression of 5-HT2B and 5-HT1B Receptors During Development of DOCA-salt Hypertension BMC Pharmacology. Sep, 2003 | Pubmed ID: 12974983 NADPH Oxidase-derived Superoxide Augments Endothelin-1-induced Venoconstriction in Mineralocorticoid Hypertension Hypertension. Sep, 2003 | Pubmed ID: 12885792 PI3-kinase-induced Hyperreactivity in DOCA-salt Hypertension is Independent of GSK-3 Activity Hypertension. Apr, 2003 | Pubmed ID: 12629035 Endothelin-1 Increases Vascular Superoxide Via Endothelin(A)-NADPH Oxidase Pathway in Low-renin Hypertension Circulation. Feb, 2003 | Pubmed ID: 12600921 5-Hydroxytryptamine(2B) Receptor Function is Enhanced in the N(omega)-nitro-L-arginine Hypertensive Rat The Journal of Pharmacology and Experimental Therapeutics. Oct, 2002 | Pubmed ID: 12235249 Phosphoinositide 3-kinase Mediates Enhanced Spontaneous and Agonist-induced Contraction in Aorta of Deoxycorticosterone Acetate-salt Hypertensive Rats Circulation Research. Aug, 2002 | Pubmed ID: 12193470 Endothelin-1-induced Venous Contraction is Maintained in DOCA-salt Hypertension; Studies with Receptor Agonists British Journal of Pharmacology. Sep, 2002 | Pubmed ID: 12183332 Endothelin Receptor Function in Mesenteric Veins from Deoxycorticosterone Acetate Salt-hypertensive Rats Journal of Hypertension. Apr, 2002 | Pubmed ID: 11910302 Serotonin-induced Contraction in Mesenteric Resistance Arteries: Signaling and Changes in Deoxycorticosterone Acetate-salt Hypertension Hypertension. Mar, 2002 | Pubmed ID: 11897772 Upregulation of Arterial Serotonin 1B and 2B Receptors in Deoxycorticosterone Acetate-salt Hypertension Hypertension. Feb, 2002 | Pubmed ID: 11882579 चुंबकीय सक्रिय सेल छंटनी द्वारा पृथक पेरिवस्कुलर ऐडीज टेस्यू से एडिपोसाइट प्रीगेनेटर का विस्तार और एडिपोजेनेसिस प्रेरण Kyan Thelen1, Nadia Ayala-Lopez2, Stephanie W. Watts2, G. Andres Contreras1 1Department of Large Animal Clinical Sciences, Michigan State University, 2Department of Pharmacology and Toxicology, Michigan State University JoVE 55818 Developmental Biology औषध अनुसंधान के लिए अलग ऊतक स्नान-अनुप्रयोगों में चिकनी मांसपेशी समारोह के मापन Brian Jespersen1, Nathan R. Tykocki2, Stephanie W. Watts1, Peter J. Cobbett1 1Department of Pharmacology and Toxicology, Michigan State University, 2Department of Pharmacology, University of Vermont College of Medicine Biology
चुंबकीय सक्रिय सेल छंटनी द्वारा पृथक पेरिवस्कुलर ऐडीज टेस्यू से एडिपोसाइट प्रीगेनेटर का विस्तार और एडिपोजेनेसिस प्रेरण Kyan Thelen1, Nadia Ayala-Lopez2, Stephanie W. Watts2, G. Andres Contreras1 1Department of Large Animal Clinical Sciences, Michigan State University, 2Department of Pharmacology and Toxicology, Michigan State University JoVE 55818 Developmental Biology
औषध अनुसंधान के लिए अलग ऊतक स्नान-अनुप्रयोगों में चिकनी मांसपेशी समारोह के मापन Brian Jespersen1, Nathan R. Tykocki2, Stephanie W. Watts1, Peter J. Cobbett1 1Department of Pharmacology and Toxicology, Michigan State University, 2Department of Pharmacology, University of Vermont College of Medicine Biology
