Stephen C. De Rosa Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center Biography Publications Institution JoVE Articles Stephen C. De Rosa has not added a biography. If you are Stephen C. De Rosa and would like to personalize this page please email our Author Liaison for assistance. Publications HIV-1-specific ELISpot Responses in HIV-1 Exposed, Uninfected Partners in Discordant Relationships, Compared to Low-Risk Controls Clinical and Vaccine Immunology : CVI. Sep, 2012 | Pubmed ID: 22971780 Silibinin Inhibits HIV-1 Infection by Reducing Cellular Activation and Proliferation PloS One. 2012 | Pubmed ID: 22848626 Optimization and Qualification of a Multiplex Bead Array to Assess Cytokine and Chemokine Production by Vaccine-specific Cells Journal of Immunological Methods. Aug, 2012 | Pubmed ID: 22626638 A Brilliant New Addition to the Fluorescent Probe Toolbox Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jun, 2012 | Pubmed ID: 22488984 Immune-correlates Analysis of an HIV-1 Vaccine Efficacy Trial The New England Journal of Medicine. Apr, 2012 | Pubmed ID: 22475592 DNA and Modified Vaccinia Virus Ankara Vaccines Encoding Multiple Cytotoxic and Helper T-lymphocyte Epitopes of Human Immunodeficiency Virus Type 1 (HIV-1) Are Safe but Weakly Immunogenic in HIV-1-uninfected, Vaccinia Virus-naive Adults Clinical and Vaccine Immunology : CVI. May, 2012 | Pubmed ID: 22398243 Vaccine Applications of Flow Cytometry Methods (San Diego, Calif.). Jul, 2012 | Pubmed ID: 22251671 Human Adenovirus-specific T Cells Modulate HIV-specific T Cell Responses to an Ad5-vectored HIV-1 Vaccine The Journal of Clinical Investigation. Jan, 2012 | Pubmed ID: 22201684 A Phase IIA Randomized Clinical Trial of a Multiclade HIV-1 DNA Prime Followed by a Multiclade RAd5 HIV-1 Vaccine Boost in Healthy Adults (HVTN204) PloS One. 2011 | Pubmed ID: 21857901 HIV-DNA Priming Alters T Cell Responses to HIV-adenovirus Vaccine Even when Responses to DNA Are Undetectable Journal of Immunology (Baltimore, Md. : 1950). Sep, 2011 | Pubmed ID: 21844392 A Trimeric, V2-deleted HIV-1 Envelope Glycoprotein Vaccine Elicits Potent Neutralizing Antibodies but Limited Breadth of Neutralization in Human Volunteers The Journal of Infectious Diseases. Apr, 2011 | Pubmed ID: 21451004 Association Between Peripheral γδ T-cell Profile and Disease Progression in Individuals Infected with HIV-1 or HIV-2 in West Africa Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2011 | Pubmed ID: 21423026 A Phase I Trial of Preventive HIV Vaccination with Heterologous Poxviral-vectors Containing Matching HIV-1 Inserts in Healthy HIV-uninfected Subjects Vaccine. Feb, 2011 | Pubmed ID: 21216311 Safety and Immunogenicity of a Replication-defective Adenovirus Type 5 HIV Vaccine in Ad5-seronegative Persons: a Randomized Clinical Trial (HVTN 054) PloS One. 2010 | Pubmed ID: 21048953 Diversity in CD8(+) T Cell Function and Epitope Breadth Among Persons with Genital Herpes Journal of Clinical Immunology. Sep, 2010 | Pubmed ID: 20635156 ORFeome Approach to the Clonal, HLA Allele-specific CD4 T-cell Response to a Complex Pathogen in Humans Journal of Immunological Methods. Aug, 2009 | Pubmed ID: 19520082 The Cytolytic Enzymes Granyzme A, Granzyme B, and Perforin: Expression Patterns, Cell Distribution, and Their Relationship to Cell Maturity and Bright CD57 Expression Journal of Leukocyte Biology. Jan, 2009 | Pubmed ID: 18820174 HIV-1 Vaccine-induced Immunity in the Test-of-concept Step Study: a Case-cohort Analysis Lancet. Nov, 2008 | Pubmed ID: 19012957 Development of an Automated Analysis System for Data from Flow Cytometric Intracellular Cytokine Staining Assays from Clinical Vaccine Trials Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2008 | Pubmed ID: 18615598 Nine-color Flow Cytometry for Accurate Measurement of T Cell Subsets and Cytokine Responses. Part I: Panel Design by an Empiric Approach Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2008 | Pubmed ID: 18383316 Nine-color Flow Cytometry for Accurate Measurement of T Cell Subsets and Cytokine Responses. Part II: Panel Performance Across Different Instrument Platforms Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2008 | Pubmed ID: 18383309 Gamma Delta+ T Cells Involvement in Viral Immune Control of Chronic Human Herpesvirus 8 Infection Journal of Immunology (Baltimore, Md. : 1950). Mar, 2008 | Pubmed ID: 18292568 Optimization and Validation of an 8-color Intracellular Cytokine Staining (ICS) Assay to Quantify Antigen-specific T Cells Induced by Vaccination Journal of Immunological Methods. May, 2007 | Pubmed ID: 17451739 Does Preserving Memory Correlate with Surviving HIV? Trends in Microbiology. Jan, 2007 | Pubmed ID: 17112728 Preservation of T Cell Proliferation Restricted by Protective HLA Alleles is Critical for Immune Control of HIV-1 Infection Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006 | Pubmed ID: 17082660 Quantum Dot Semiconductor Nanocrystals for Immunophenotyping by Polychromatic Flow Cytometry Nature Medicine. Aug, 2006 | Pubmed ID: 16862156 HIV Nonprogressors Preferentially Maintain Highly Functional HIV-specific CD8+ T Cells Blood. Jun, 2006 | Pubmed ID: 16467198 Characterization of Subsets of CD4+ Memory T Cells Reveals Early Branched Pathways of T Cell Differentiation in Humans Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15905333 Multicolor Immunophenotyping: Human Mature Immune System Methods in Cell Biology. 2004 | Pubmed ID: 15603443 Vaccination in Humans Generates Broad T Cell Cytokine Responses Journal of Immunology (Baltimore, Md. : 1950). Nov, 2004 | Pubmed ID: 15494483 Flow Cytometric Analysis of Vaccine Responses: How Many Colors Are Enough? Clinical Immunology (Orlando, Fla.). Mar, 2004 | Pubmed ID: 15047198 A Potent Anti-HIV Immunotoxin Blocks Spreading Infection by Primary HIV Type 1 Isolates in Multiple Cell Types AIDS Research and Human Retroviruses. Feb, 2004 | Pubmed ID: 15018701 Ontogeny of Gamma Delta T Cells in Humans Journal of Immunology (Baltimore, Md. : 1950). Feb, 2004 | Pubmed ID: 14734745 Sensitive and Viable Identification of Antigen-specific CD8+ T Cells by a Flow Cytometric Assay for Degranulation Journal of Immunological Methods. Oct, 2003 | Pubmed ID: 14580882 Optimized Lymphocyte Isolation Methods for Analysis of Chemokine Receptor Expression Journal of Immunological Methods. Aug, 2003 | Pubmed ID: 12969561 Beyond Six Colors: a New Era in Flow Cytometry Nature Medicine. Jan, 2003 | Pubmed ID: 12514723 Human Immunodeficiency Virus Type 1 Neutralization Measured by Flow Cytometric Quantitation of Single-round Infection of Primary Human T Cells Journal of Virology. May, 2002 | Pubmed ID: 11967298 Optælling af Major perifert blod leukocytpopulationer for multicenter kliniske undersøgelser med en Whole Blood fænotypebestemmelse Assay Tiffany R. Hensley1, Austin B. Easter1, Sarah E. Gerdts1, Stephen C. De Rosa1, Antje Heit1, M. Juliana McElrath1, Erica Andersen-Nissen1 1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center JoVE 4302 Immunology and Infection
Optælling af Major perifert blod leukocytpopulationer for multicenter kliniske undersøgelser med en Whole Blood fænotypebestemmelse Assay Tiffany R. Hensley1, Austin B. Easter1, Sarah E. Gerdts1, Stephen C. De Rosa1, Antje Heit1, M. Juliana McElrath1, Erica Andersen-Nissen1 1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center JoVE 4302 Immunology and Infection