Stephen Lye

Publications

• Glucocorticoids Modulate Multidrug Resistance Transporters in the First Trimester Human Placenta
  Journal of Cellular and Molecular Medicine. Apr, 2018  |   Pubmed ID: 29691980
• Maternal Blood Endotoxin Activity in Pregnancies Complicated by Preterm Premature Rupture of Membranes
  The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. Apr, 2018  |   Pubmed ID: 29656690
• Reply
  American Journal of Obstetrics and Gynecology. Mar, 2018  |   Pubmed ID: 29604285
• Nurturing Care for Young Children Under Conditions of Fragility and Conflict
  New Directions for Child and Adolescent Development. Mar, 2018  |   Pubmed ID: 29537179
• Extracellular Vesicle RNAs Reflect Placenta Dysfunction and Are a Biomarker Source for Preterm Labour
  Journal of Cellular and Molecular Medicine. May, 2018  |   Pubmed ID: 29516617
• Chorioamnionitis Induces a Specific Signature of Placental ABC Transporters Associated with an Increase of MiR-331-5p in the Human Preterm Placenta
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2018  |   Pubmed ID: 29402780
• Comparative Analysis of Gene Expression in Maternal Peripheral Blood and Monocytes During Spontaneous Preterm Labor
  American Journal of Obstetrics and Gynecology. Mar, 2018  |   Pubmed ID: 29305255
• Differential Expression of Myometrial AP-1 Proteins During Gestation and Labour
  Journal of Cellular and Molecular Medicine. Jan, 2018  |   Pubmed ID: 28945005
• Analysis of S1P Receptor Expression by Uterine Immune Cells Using Standardized Multi-parametric Flow Cytometry
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 28434167
• HoxA10 and HoxA11 Regulate the Expression of Contraction-Associated Proteins and Contribute to Regionalized Myometrium Phenotypes in Women
  Reproductive Sciences (Thousand Oaks, Calif.). Jan, 2018  |   Pubmed ID: 28372536
• Progesterone Via Its Type-A Receptor Promotes Myometrial Gap Junction Coupling
  Scientific Reports. Oct, 2017  |   Pubmed ID: 29042599
• Maternal Vascular Malperfusion and Adverse Perinatal Outcomes in Low-Risk Nulliparous Women
  Obstetrics and Gynecology. Nov, 2017  |   Pubmed ID: 29016509
• Activated NK Cells Cause Placental Dysfunction and Miscarriages in Fetal Alloimmune Thrombocytopenia
  Nature Communications. 08, 2017  |   Pubmed ID: 28794456
• Prioritizing Research for Integrated Implementation of Early Childhood Development and Maternal, Newborn, Child and Adolescent Health and Nutrition Platforms
  Journal of Global Health. Jun, 2017  |   Pubmed ID: 28685048
• Peripheral Maternal Leukocytes Are Activated in Response to Cytokines Secreted by Uterine Tissues of Pregnant Women
  Cellular & Molecular Immunology. Jul, 2017  |   Pubmed ID: 28603281
• Immunophenotyping and Activation Status of Maternal Peripheral Blood Leukocytes During Pregnancy and Labour, Both Term and Preterm
  Journal of Cellular and Molecular Medicine. Oct, 2017  |   Pubmed ID: 28429508
• Definitive Class I Human Leukocyte Antigen Expression in Gestational Placentation: HLA-F, HLA-E, HLA-C, and HLA-G in Extravillous Trophoblast Invasion on Placentation, Pregnancy, and Parturition
  American Journal of Reproductive Immunology (New York, N.Y. : 1989). 06, 2017  |   Pubmed ID: 28185362
• Nurturing Care: Promoting Early Childhood Development
  Lancet (London, England). 01, 2017  |   Pubmed ID: 27717615
• Early Childhood Development: the Foundation of Sustainable Development
  Lancet (London, England). 01, 2017  |   Pubmed ID: 27717607
• Human DNK Cell Function is Differentially Regulated by Extrinsic Cellular Engagement and Intrinsic Activating Receptors in First and Second Trimester Pregnancy
  Cellular & Molecular Immunology. Feb, 2017  |   Pubmed ID: 26277900
• Dual Energy X-Ray Absorptiometry Compared with Anthropometry in Relation to Cardio-Metabolic Risk Factors in a Young Adult Population: Is the 'Gold Standard' Tarnished?
  PloS One. 2016  |   Pubmed ID: 27622523
• Preeclampsia is Associated with Low Placental Transthyretin Levels
  Taiwanese Journal of Obstetrics & Gynecology. Jun, 2016  |   Pubmed ID: 27343320
• Maternal Whole Blood Gene Expression at 18 and 28 Weeks of Gestation Associated with Spontaneous Preterm Birth in Asymptomatic Women
  PloS One. 2016  |   Pubmed ID: 27333071
• Matrix Metalloproteinase Expression in the Rat Myometrium During Pregnancy, Term Labor, and Postpartum
  Biology of Reproduction. 07, 2016  |   Pubmed ID: 27251092
• Molecular Evidence of Functional Progesterone Withdrawal in Human Myometrium
  Nature Communications. May, 2016  |   Pubmed ID: 27220952
• HoxA13 Stimulates Myometrial Cells to Secrete IL-1β and Enhance the Expression of Contraction-Associated Proteins
  Endocrinology. 05, 2016  |   Pubmed ID: 26982635
• Summary and Synthesis of Current Knowledge
  Early Human Development. Mar, 2016  |   Pubmed ID: 26852165
• Introductory Editorial: Effects of Maternal Physical Activity on the Fetus
  Early Human Development. Mar, 2016  |   Pubmed ID: 26846466
• Static Mechanical Loading Influences the Expression of Extracellular Matrix and Cell Adhesion Proteins in Vaginal Cells Derived From Premenopausal Women With Severe Pelvic Organ Prolapse
  Reproductive Sciences (Thousand Oaks, Calif.). 08, 2016  |   Pubmed ID: 26823071
• Impact of Maternal Physical Activity on Fetal Breathing and Body Movement--A Review
  Early Human Development. Mar, 2016  |   Pubmed ID: 26811196
• Characterization and Novel Analyses of Acute Stress Response Patterns in a Population-based Cohort of Young Adults: Influence of Gender, Smoking, and BMI
  Stress (Amsterdam, Netherlands). 2016  |   Pubmed ID: 26809721
• Hypothalamic-pituitary-adrenal Axis Activity Under Resting Conditions and Cardiovascular Risk Factors in Adolescents
  Psychoneuroendocrinology. Apr, 2016  |   Pubmed ID: 26802599
• Comparative Characterization of Vaginal Cells Derived From Premenopausal Women With and Without Severe Pelvic Organ Prolapse
  Reproductive Sciences (Thousand Oaks, Calif.). 07, 2016  |   Pubmed ID: 26763525
• Elevated MRNA Expression of PGF2α Receptor Splice Variant 2(FP-V2) in Human Decidua is Associated with Incomplete Mifepristone-misoprostol-induced Early Medical Abortion by Regulation of Interleukin-8
  The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. Nov, 2016  |   Pubmed ID: 26744271
• Changes in Vascular Extracellular Matrix Composition During Decidual Spiral Arteriole Remodeling in Early Human Pregnancy
  Histology and Histopathology. May, 2016  |   Pubmed ID: 26602431
• To Serve and to Protect: the Role of Decidual Innate Immune Cells on Human Pregnancy
  Cell and Tissue Research. Jan, 2016  |   Pubmed ID: 26572540
• In Vivo Evidence of the Androgen Receptor in Association With Myometrial Cell Proliferation and Apoptosis
  Reproductive Sciences (Thousand Oaks, Calif.). Feb, 2016  |   Pubmed ID: 26342051
• Quantitative Large Scale Gene Expression Profiling from Human Stem Cell Culture Micro Samples Using Multiplex Pre-amplification
  Systems Biology in Reproductive Medicine. 2016  |   Pubmed ID: 26237078
• Improving Customized Fetal Biometry by Longitudinal Modelling
  The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2016  |   Pubmed ID: 26169714
• HoxA13 Regulates Phenotype Regionalization of Human Pregnant Myometrium
  The Journal of Clinical Endocrinology and Metabolism. Dec, 2015  |   Pubmed ID: 26485220
• Impact of Bacterial and Viral Challenge on Multidrug Resistance in First- and Third-trimester Human Placenta
  The American Journal of Pathology. Jun, 2015  |   Pubmed ID: 25963552
• Stretch-induced Human Myometrial Cytokines Enhance Immune Cell Recruitment Via Endothelial Activation
  Cellular & Molecular Immunology. Mar, 2015  |   Pubmed ID: 24882387
• Identification of a Novel Neutrophil Population: Proangiogenic Granulocytes in Second-trimester Human Decidua
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2014  |   Pubmed ID: 25135830
• Leukocyte Driven-decidual Angiogenesis in Early Pregnancy
  Cellular & Molecular Immunology. Nov, 2014  |   Pubmed ID: 25066422
• Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
  PLoS Genetics. Jul, 2014  |   Pubmed ID: 25010111
• Inhibition of Infection-mediated Preterm Birth by Administration of Broad Spectrum Chemokine Inhibitor in Mice
  Journal of Cellular and Molecular Medicine. Sep, 2014  |   Pubmed ID: 24894878
• Connexin31.1 (Gjb5) Deficiency Blocks Trophoblast Stem Cell Differentiation and Delays Placental Development
  Stem Cells and Development. Nov, 2014  |   Pubmed ID: 24866916
• A New Role for Monocytes in Modulating Myometrial Inflammation During Human Labor
  Biology of Reproduction. Jul, 2014  |   Pubmed ID: 24829032
• Investigation of Genetic Variants, Birthweight and Hypothalamic-pituitary-adrenal Axis Function Suggests a Genetic Variant in the SERPINA6 Gene is Associated with Corticosteroid Binding Globulin in the Western Australia Pregnancy Cohort (Raine) Study
  PloS One. 2014  |   Pubmed ID: 24691024
• Expression of Extracellular Matrix-remodeling Proteins is Altered in Vaginal Tissue of Premenopausal Women with Severe Pelvic Organ Prolapse
  Reproductive Sciences (Thousand Oaks, Calif.). Jun, 2014  |   Pubmed ID: 24343133
• Association of a Body Mass Index Genetic Risk Score with Growth Throughout Childhood and Adolescence
  PloS One. 2013  |   Pubmed ID: 24244521
• Development and Validation of Primary Human Myometrial Cell Culture Models to Study Pregnancy and Labour
  BMC Pregnancy and Childbirth. 2013  |   Pubmed ID: 23445904
• The All Our Babies Pregnancy Cohort: Design, Methods, and Participant Characteristics
  BMC Pregnancy and Childbirth. 2013  |   Pubmed ID: 23445747
• DREAM Mediated Regulation of GCM1 in the Human Placental Trophoblast
  PloS One. 2013  |   Pubmed ID: 23300953
• Expression and Function of Myometrial PSF Suggest a Role in Progesterone Withdrawal and the Initiation of Labor
  Molecular Endocrinology (Baltimore, Md.). Aug, 2012  |   Pubmed ID: 22669741
• Common Variants at 12q15 and 12q24 Are Associated with Infant Head Circumference
  Nature Genetics. Apr, 2012  |   Pubmed ID: 22504419
• Expression of Genes Encoding Smooth Muscle Contractile Proteins in Vaginal Tissue of Women with and Without Pelvic Organ Prolapse
  Neurourology and Urodynamics. Jan, 2012  |   Pubmed ID: 22038928
• An Integrated Systems Biology Approach to the Study of Preterm Birth Using "-omic" Technology--a Guideline for Research
  BMC Pregnancy and Childbirth. Oct, 2011  |   Pubmed ID: 21992798
• Consensus PP1 Binding Motifs Regulate Transcriptional Corepression and Alternative RNA Splicing Activities of the Steroid Receptor Coregulators, P54nrb and PSF
  Molecular Endocrinology (Baltimore, Md.). Jul, 2011  |   Pubmed ID: 21566083
• Association of Genetic Loci with Glucose Levels in Childhood and Adolescence: a Meta-analysis of over 6,000 Children
  Diabetes. Jun, 2011  |   Pubmed ID: 21515849
• Expression of Bone Morphogenetic Protein-1 in Vaginal Tissue of Women with Severe Pelvic Organ Prolapse
  American Journal of Obstetrics and Gynecology. Jun, 2011  |   Pubmed ID: 21397208
• Nodal Signals Through Activin Receptor-like Kinase 7 to Inhibit Trophoblast Migration and Invasion: Implication in the Pathogenesis of Preeclampsia
  The American Journal of Pathology. Mar, 2011  |   Pubmed ID: 21356369
• All Our Babies Cohort Study: Recruitment of a Cohort to Predict Women at Risk of Preterm Birth Through the Examination of Gene Expression Profiles and the Environment
  BMC Pregnancy and Childbirth. Dec, 2010  |   Pubmed ID: 21192811
• Characterization of the Myometrial Transcriptome and Biological Pathways of Spontaneous Human Labor at Term
  Journal of Perinatal Medicine. Nov, 2010  |   Pubmed ID: 20629487
• LOX Family Enzymes Expression in Vaginal Tissue of Premenopausal Women with Severe Pelvic Organ Prolapse
  International Urogynecology Journal. Nov, 2010  |   Pubmed ID: 20559617
• Vascular-leukocyte Interactions: Mechanisms of Human Decidual Spiral Artery Remodeling in Vitro
  The American Journal of Pathology. Aug, 2010  |   Pubmed ID: 20558572
• Expression and Regulation of Prostaglandin Receptors in the Human Placenta and Fetal Membranes at Term and Preterm
  Reproduction, Fertility, and Development. 2010  |   Pubmed ID: 20450832
• Developmental Regulation of Cardiovascular Function is Dependent on Both Genotype and Environment
  American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2009  |   Pubmed ID: 19783772
• P54nrb is a Transcriptional Corepressor of the Progesterone Receptor That Modulates Transcription of the Labor-associated Gene, Connexin 43 (Gja1)
  Molecular Endocrinology (Baltimore, Md.). Aug, 2009  |   Pubmed ID: 19423654
• Transcriptional Activity of Androgen Receptor is Modulated by Two RNA Splicing Factors, PSF and P54nrb
  Molecular and Cellular Biology. Jul, 2007  |   Pubmed ID: 17452459
• Fetal Signals and Parturition
  The Journal of Obstetrics and Gynaecology Research. Dec, 2005  |   Pubmed ID: 16343248
• Effect of Labor on Glucocorticoid Receptor (GR(Total), GRalpha, and GRbeta) Proteins in Ovine Intrauterine Tissues
  Journal of the Society for Gynecologic Investigation. Apr, 2003  |   Pubmed ID: 12699875
• Hypoxia-inducible Factor-1 Mediates the Biological Effects of Oxygen on Human Trophoblast Differentiation Through TGFbeta(3)
  The Journal of Clinical Investigation. Mar, 2000  |   Pubmed ID: 10712429
• Inhibition of TGF-beta 3 Restores the Invasive Capability of Extravillous Trophoblasts in Preeclamptic Pregnancies
  The Journal of Clinical Investigation. Jun, 1999  |   Pubmed ID: 10377170