Steven J. McElroy Division of Neonatology, Stead Family Department of Pediatrics University of Iowa Biography Publications Institution JoVE Articles Steven J. McElroy has not added a biography. If you are Steven J. McElroy and would like to personalize this page please email our Author Liaison for assistance. Publications The Paneth Cell: The Curator and Defender of the Immature Small Intestine Frontiers in Immunology. 2020 | Pubmed ID: 32308658 Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner Nutrients. Mar, 2020 | Pubmed ID: 32224880 Another Brick in the Wall: Discovering the Role of Necroptosis in Neonatal Necrotizing Enterocolitis Cellular and Molecular Gastroenterology and Hepatology. 2020 | Pubmed ID: 31904352 Fetal Exposure to Maternal Inflammation Interrupts Murine Intestinal Development and Increases Susceptibility to Neonatal Intestinal Injury Disease Models & Mechanisms. 10, 2019 | Pubmed ID: 31537532 A Direct Comparison of Mouse and Human Intestinal Development Using Epithelial Gene Expression Patterns Pediatric Research. Jun, 2019 | Pubmed ID: 31242501 Dithizone-induced Paneth Cell Disruption Significantly Decreases Intestinal Perfusion in the Murine Small Intestine Journal of Pediatric Surgery. Nov, 2019 | Pubmed ID: 30857731 Loss of Murine Paneth Cell Function Alters the Immature Intestinal Microbiome and Mimics Changes Seen in Neonatal Necrotizing Enterocolitis PloS One. 2018 | Pubmed ID: 30273395 Limited Achievement of NIH Research Independence by Pediatric K Award Recipients Pediatric Research. Oct, 2018 | Pubmed ID: 29904137 Lipopolysaccharide-induced Maternal Inflammation Induces Direct Placental Injury Without Alteration in Placental Blood Flow and Induces a Secondary Fetal Intestinal Injury That Persists into Adulthood American Journal of Reproductive Immunology (New York, N.Y. : 1989). 05, 2018 | Pubmed ID: 29369434 Name and Characteristics of National Institutes of Health R01-Funded Pediatric Physician-Scientists: Hope and Challenges for the Vanishing Pediatric Physician-Scientists JAMA Pediatrics. Jan, 2018 | Pubmed ID: 29340570 The Science and Necessity of Using Animal Models in the Study of Necrotizing Enterocolitis Seminars in Pediatric Surgery. Feb, 2018 | Pubmed ID: 29275813 Jack Widness: the Importance of Connections Pediatric Research. 04, 2018 | Pubmed ID: 29244795 Intraoperative High-Frequency Jet Ventilation Is Equivalent to Conventional Ventilation During Patent Ductus Arteriosus Ligation World Journal for Pediatric & Congenital Heart Surgery. 09, 2017 | Pubmed ID: 28901229 Paneth-cell-disruption-induced Necrotizing Enterocolitis in Mice Requires Live Bacteria and Occurs Independently of TLR4 Signaling Disease Models & Mechanisms. 06, 2017 | Pubmed ID: 28450472 Targeting IL-17A Attenuates Neonatal Sepsis Mortality Induced by IL-18 Proceedings of the National Academy of Sciences of the United States of America. May, 2016 | Pubmed ID: 27114524 Development of the Neonatal Intestinal Microbiome and Its Association With Necrotizing Enterocolitis Clinical Therapeutics. 04, 2016 | Pubmed ID: 26852144 Intrauterine Growth Restriction Alters Mouse Intestinal Architecture During Development PloS One. 2016 | Pubmed ID: 26745886 Evaluation of Hematologic Variables in Newborn C57/BL6 Mice Up to Day 35 Veterinary Clinical Pathology. Mar, 2016 | Pubmed ID: 26717267 The Role of Bacteria in Necrotizing Enterocolitis: Understanding the Forest for the Trees Neonatology. 2015 | Pubmed ID: 26278707 Tumor Necrosis Factor Induces Developmental Stage-dependent Structural Changes in the Immature Small Intestine Mediators of Inflammation. 2014 | Pubmed ID: 25242872 The ErbB4 Ligand Neuregulin-4 Protects Against Experimental Necrotizing Enterocolitis The American Journal of Pathology. Oct, 2014 | Pubmed ID: 25216938 Correlation of Abdominal RSO2 with Superior Mesenteric Artery Velocities in Preterm Infants Journal of Perinatology : Official Journal of the California Perinatal Association. Aug, 2013 | Pubmed ID: 23392317 Paneth Cells and Necrotizing Enterocolitis: a Novel Hypothesis for Disease Pathogenesis Neonatology. 2013 | Pubmed ID: 23006982 Ein murines Modell der fetalen Exposition gegenüber mütterlicher Entzündung, um die Auswirkungen der akuten Chorioamnionitis auf die Darmentwicklung von Neugeborenen zu untersuchen Brian A. Juber1, Timothy G. Elgin1, Erin M. Fricke2, Huyiu Gong1, Jeffrey Reese3, Steven J. McElroy1,4 1Division of Neonatology, Stead Family Department of Pediatrics, University of Iowa, 2Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, University of Iowa, 3Division of Neonatology, Department of Pediatrics, Vanderbilt University, 4Department of Microbiology & Immunology, University of Iowa JoVE 61464 Medicine
Ein murines Modell der fetalen Exposition gegenüber mütterlicher Entzündung, um die Auswirkungen der akuten Chorioamnionitis auf die Darmentwicklung von Neugeborenen zu untersuchen Brian A. Juber1, Timothy G. Elgin1, Erin M. Fricke2, Huyiu Gong1, Jeffrey Reese3, Steven J. McElroy1,4 1Division of Neonatology, Stead Family Department of Pediatrics, University of Iowa, 2Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, University of Iowa, 3Division of Neonatology, Department of Pediatrics, Vanderbilt University, 4Department of Microbiology & Immunology, University of Iowa JoVE 61464 Medicine