Steven A. Stacker

Publications

• Chronic Stress in Mice Remodels Lymph Vasculature to Promote Tumour Cell Dissemination
  Nature Communications. 2016  |   Pubmed ID: 26925549
• Vegf-d Promotes Pulmonary Oedema in Hyperoxic Acute Lung Injury
  The Journal of Pathology. Feb, 2016  |   Pubmed ID: 26924464
• Exploring the Role of Endothelium in the Tumour Response to Anti-angiogenic Therapy
  Biochemical Society Transactions. Dec, 2014  |   Pubmed ID: 25399572
• Expression and Purification of Bioactive, Low-endotoxin Recombinant Human Vitronectin
  BioTechniques. Jun, 2014  |   Pubmed ID: 24924394
• Lymphangiogenesis and Lymphatic Vessel Remodelling in Cancer
  Nature Reviews. Cancer. Mar, 2014  |   Pubmed ID: 24561443
• Ccbe1 Regulates Vegfc-mediated Induction of Vegfr3 Signaling During Embryonic Lymphangiogenesis
  Development (Cambridge, England). Mar, 2014  |   Pubmed ID: 24523457
• Wnt5a Induces Ryk-dependent and -independent Effects on Callosal Axon and Dendrite Growth
  Growth Factors (Chur, Switzerland). Feb, 2014  |   Pubmed ID: 24471468
• VEGFD Regulates Blood Vascular Development by Modulating SOX18 Activity
  Blood. Feb, 2014  |   Pubmed ID: 24269955
• Arap3 is Dysregulated in a Mouse Model of Hypotrichosis-lymphedema-telangiectasia and Regulates Lymphatic Vascular Development
  Human Molecular Genetics. Mar, 2014  |   Pubmed ID: 24163130
• Tissues in Different Anatomical Sites Can Sculpt and Vary the Tumor Microenvironment to Affect Responses to Therapy
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2014  |   Pubmed ID: 24048441
• Lymphovascular and Neural Regulation of Metastasis: Shared Tumour Signalling Pathways and Novel Therapeutic Approaches
  Best Practice & Research. Clinical Anaesthesiology. Dec, 2013  |   Pubmed ID: 24267548
• A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYK
  PloS One. 2013  |   Pubmed ID: 24058687
• Signaling for Lymphangiogenesis Via VEGFR-3 is Required for the Early Events of Metastasis
  Clinical & Experimental Metastasis. Aug, 2013  |   Pubmed ID: 23591595
• Ryk, a Receptor Regulating Wnt5a-mediated Neurogenesis and Axon Morphogenesis of Ventral Midbrain Dopaminergic Neurons
  Stem Cells and Development. Aug, 2013  |   Pubmed ID: 23517308
• Vascular Endothelial Growth Factor-d Modulates Caliber and Function of Initial Lymphatics in the Dermis
  The Journal of Investigative Dermatology. Aug, 2013  |   Pubmed ID: 23439394
• The VEGF Signaling Pathway in Cancer: the Road Ahead
  Chinese Journal of Cancer. Jun, 2013  |   Pubmed ID: 23419196
• The Propeptides of VEGF-D Determine Heparin Binding, Receptor Heterodimerization, and Effects on Tumor Biology
  The Journal of Biological Chemistry. Mar, 2013  |   Pubmed ID: 23404505
• Tumor Location and Nature of Lymphatic Vessels Are Key Determinants of Cancer Metastasis
  Clinical & Experimental Metastasis. Mar, 2013  |   Pubmed ID: 23124573
• The Wnt Coreceptor Ryk Regulates Wnt/planar Cell Polarity by Modulating the Degradation of the Core Planar Cell Polarity Component Vangl2
  The Journal of Biological Chemistry. Dec, 2012  |   Pubmed ID: 23144463
• The Connection Between Lymphangiogenic Signalling and Prostaglandin Biology: a Missing Link in the Metastatic Pathway
  Oncotarget. Aug, 2012  |   Pubmed ID: 23097685
• Remodeling of the Lymphatic Vasculature During Mouse Mammary Gland Morphogenesis is Mediated Via Epithelial-derived Lymphangiogenic Stimuli
  The American Journal of Pathology. Dec, 2012  |   Pubmed ID: 23063660
• Vascular Endothelial Growth Factor-D: Signaling Mechanisms, Biology, and Clinical Relevance
  Growth Factors (Chur, Switzerland). Oct, 2012  |   Pubmed ID: 22817635
• The Wnt Receptor Ryk Plays a Role in Mammalian Planar Cell Polarity Signaling
  The Journal of Biological Chemistry. Aug, 2012  |   Pubmed ID: 22773843
• Lymphatic Vessel Density in Primary Melanomas Predicts Sentinel Lymph Node Status and Risk of Metastasis
  Histopathology. Oct, 2012  |   Pubmed ID: 22734806
• VEGF-D Promotes Tumor Metastasis by Regulating Prostaglandins Produced by the Collecting Lymphatic Endothelium
  Cancer Cell. Feb, 2012  |   Pubmed ID: 22340592
• Preparation of Human Vascular Endothelial Growth Factor-D for Structural and Preclinical Therapeutic Studies
  Protein Expression and Purification. Mar, 2012  |   Pubmed ID: 22261343
• A Role for Bone Morphogenetic Protein-4 in Lymph Node Vascular Remodeling and Primary Tumor Growth
  Cancer Research. Oct, 2011  |   Pubmed ID: 21868759
• Proteolytic Processing of Vascular Endothelial Growth Factor-D is Essential for Its Capacity to Promote the Growth and Spread of Cancer
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2011  |   Pubmed ID: 21515745
• Wnt5a Regulates Midbrain Dopaminergic Axon Growth and Guidance
  PloS One. 2011  |   Pubmed ID: 21483795
• The VD1 Neutralizing Antibody to Vascular Endothelial Growth Factor-D: Binding Epitope and Relationship to Receptor Binding
  Journal of Molecular Biology. Apr, 2011  |   Pubmed ID: 21315726
• Targeting Lymphatic Vessel Functions Through Tyrosine Kinases
  Journal of Angiogenesis Research. 2010  |   Pubmed ID: 20698997
• Vascular Endothelial Growth Factor-D Over-expressing Tumor Cells Induce Differential Effects on Uterine Vasculature in a Mouse Model of Endometrial Cancer
  Reproductive Biology and Endocrinology : RB&E. 2010  |   Pubmed ID: 20615255
• Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/beta-catenin Pathway in Vivo
  PLoS Genetics. Jan, 2010  |   Pubmed ID: 20084116
• From Anti-angiogenesis to Anti-lymphangiogenesis: Emerging Trends in Cancer Therapy
  Lymphatic Research and Biology. 2008  |   Pubmed ID: 19093789
• Sox18 Induces Development of the Lymphatic Vasculature in Mice
  Nature. Dec, 2008  |   Pubmed ID: 18931657
• Importance of Wnt Signaling in the Tumor Stroma Microenvironment
  Current Cancer Drug Targets. Sep, 2008  |   Pubmed ID: 18781892
• Targeting Tumor Stroma
  Current Cancer Drug Targets. Sep, 2008  |   Pubmed ID: 18781890
• Molecular Control of Lymphatic Metastasis
  Annals of the New York Academy of Sciences. 2008  |   Pubmed ID: 18519975
• Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos
  Molecular and Cellular Biology. Aug, 2008  |   Pubmed ID: 18519586
• A System for Quantifying the Patterning of the Lymphatic Vasculature
  Growth Factors (Chur, Switzerland). Dec, 2007  |   Pubmed ID: 18365872
• Molecular Pathways for Lymphangiogenesis and Their Role in Human Disease
  Novartis Foundation Symposium. 2007  |   Pubmed ID: 17534064
• Distinct Roles of Vascular Endothelial Growth Factor-D in Lymphangiogenesis and Metastasis
  The American Journal of Pathology. Apr, 2007  |   Pubmed ID: 17392173
• Proprotein Convertases Promote Processing of VEGF-D, a Critical Step for Binding the Angiogenic Receptor VEGFR-2
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2007  |   Pubmed ID: 17242158
• Lymphangiogenic Growth Factor Responsiveness is Modulated by Postnatal Lymphatic Vessel Maturation
  The American Journal of Pathology. Aug, 2006  |   Pubmed ID: 16877368
• The Wnt Receptor Ryk is Required for Wnt5a-mediated Axon Guidance on the Contralateral Side of the Corpus Callosum
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006  |   Pubmed ID: 16723543
• Lymphatic Vessels in Cancer Metastasis: Bridging the Gaps
  Carcinogenesis. Sep, 2006  |   Pubmed ID: 16597644
• Tumor Lymphangiogenesis and Metastatic Spread-new Players Begin to Emerge
  International Journal of Cancer. Oct, 2006  |   Pubmed ID: 16557570
• Lymphatic Endothelium: an Important Interactive Surface for Malignant Cells
  Pulmonary Pharmacology & Therapeutics. 2006  |   Pubmed ID: 16286238
• Mechanisms of Lymphangiogenesis: Targets for Blocking the Metastatic Spread of Cancer
  Current Cancer Drug Targets. Dec, 2005  |   Pubmed ID: 16375662
• Vascular Endothelial Growth Factor-D Induces Lymphangiogenesis and Lymphatic Metastasis in Models of Ductal Pancreatic Cancer
  International Journal of Oncology. Sep, 2005  |   Pubmed ID: 16077915
• Vascular Endothelial Growth Factor D is Dispensable for Development of the Lymphatic System
  Molecular and Cellular Biology. Mar, 2005  |   Pubmed ID: 15743836
• Focus on Lymphangiogenesis in Tumor Metastasis
  Cancer Cell. Feb, 2005  |   Pubmed ID: 15710325
• Pathogenesis of Persistent Lymphatic Vessel Hyperplasia in Chronic Airway Inflammation
  The Journal of Clinical Investigation. Feb, 2005  |   Pubmed ID: 15668734
• Lymphangiogenic Growth Factors As Markers of Tumor Metastasis
  APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2004  |   Pubmed ID: 15563315
• Molecular Regulation of the VEGF Family -- Inducers of Angiogenesis and Lymphangiogenesis
  APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2004  |   Pubmed ID: 15563310
• Expression of Vascular Endothelial Growth Factor Receptor-3 by Lymphatic Endothelial Cells is Associated with Lymph Node Metastasis in Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2004  |   Pubmed ID: 15297417
• Adenoviral Catheter-mediated Intramyocardial Gene Transfer Using the Mature Form of Vascular Endothelial Growth Factor-D Induces Transmural Angiogenesis in Porcine Heart
  Circulation. Mar, 2004  |   Pubmed ID: 14967735
• A Study of VEGF and Its Receptors in Two Rat Models of Proteinuria
  Nephron. Physiology. 2004  |   Pubmed ID: 14752241
• Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue
  Human Gene Therapy. Oct, 2003  |   Pubmed ID: 14577925
• Vascular Endothelial Growth Factor-D Expression in Human Atherosclerotic Lesions
  Cardiovascular Research. Oct, 2003  |   Pubmed ID: 14553837
• Plasmin Activates the Lymphangiogenic Growth Factors VEGF-C and VEGF-D
  The Journal of Experimental Medicine. Sep, 2003  |   Pubmed ID: 12963694
• Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability Yet Are Uniformly Active Mitogens
  The Journal of Biological Chemistry. Sep, 2003  |   Pubmed ID: 12867434
• VEGF-D is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered into Skeletal Muscle Via Adenoviruses
  Circulation Research. May, 2003  |   Pubmed ID: 12714562
• EGFR Blockade with ZD1839 ("Iressa") Potentiates the Antitumor Effects of Single and Multiple Fractions of Ionizing Radiation in Human A431 Squamous Cell Carcinoma. Epidermal Growth Factor Receptor
  International Journal of Radiation Oncology, Biology, Physics. Mar, 2003  |   Pubmed ID: 12573759
• Pseudocowpox Virus Encodes a Homolog of Vascular Endothelial Growth Factor
  Virology. Jan, 2003  |   Pubmed ID: 12573575
• Regenerating Lizard Tails: a New Model for Investigating Lymphangiogenesis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003  |   Pubmed ID: 12514111
• Molecular Control of Lymphangiogenesis
  BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Nov, 2002  |   Pubmed ID: 12386934
• Lymphangiogenesis and Cancer Metastasis
  Nature Reviews. Cancer. Aug, 2002  |   Pubmed ID: 12154350
• The Angiogenic and Lymphangiogenic Factor Vascular Endothelial Growth Factor-D Exhibits a Paracrine Mode of Action in Cancer
  Growth Factors (Chur, Switzerland). Jun, 2002  |   Pubmed ID: 12148568
• The Role of Tumor Lymphangiogenesis in Metastatic Spread
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2002  |   Pubmed ID: 12087053
• Adenovirus Encoding Vascular Endothelial Growth Factor-D Induces Tissue-specific Vascular Patterns in Vivo
  Blood. Jun, 2002  |   Pubmed ID: 12036873
• Renal Ischemia-reperfusion Increases Endothelial VEGFR-2 Without Increasing VEGF or VEGFR-1 Expression
  Kidney International. May, 2002  |   Pubmed ID: 11967019