Steven L. Carroll Hollings Cancer Center Medical University of South Carolina Biography Publications Institution JoVE Articles Steven L. Carroll has not added a biography. If you are Steven L. Carroll and would like to personalize this page please email our Author Liaison for assistance. Publications Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival The American Journal of Pathology. Sep, 2023 | Pubmed ID: 37328102 LPAR1 and Aberrantly Expressed LPAR3 Differentially Promote the Migration and Proliferation of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Mar, 2023 | Pubmed ID: 36416236 Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table Biopreservation and Biobanking. Feb, 2023 | Pubmed ID: 35507966 Developmental, Neurochemical, and Behavioral Analyses of ErbB4 Cyt-1 Knockout Mice Journal of Neurochemistry. Jun, 2022 | Pubmed ID: 35523590 The RASopathies: Biology, Genetics and Therapeutic Options Advances in Cancer Research. 2022 | Pubmed ID: 35101235 Suppression of Fli-1 Protects Against Pericyte Loss and Cognitive Deficits in Alzheimer's Disease Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2022 | Pubmed ID: 35038582 R-Ras Subfamily Proteins Elicit Distinct Physiologic Effects and Phosphoproteome Alterations in Neurofibromin-null MPNST Cells Cell Communication and Signaling : CCS. Sep, 2021 | Pubmed ID: 34530870 The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change The American Journal of Pathology. Sep, 2021 | Pubmed ID: 34111428 The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33925820 Establishment and Genomic Characterization of a Sporadic Malignant Peripheral Nerve Sheath Tumor Cell Line Scientific Reports. Mar, 2021 | Pubmed ID: 33707600 Each Patient is a Research Biorepository: Informatics-enabled Research on Surplus Clinical Specimens Via the Living BioBank Journal of the American Medical Informatics Association : JAMIA. 01, 2021 | Pubmed ID: 33166379 Chemoembolizing Hepatocellular Carcinoma with Microsphere Cored with Arsenic Trioxide Microcrystal Drug Delivery. Nov, 2020 | Pubmed ID: 33307843 Assessing Interobserver Variability and Accuracy in the Histological Diagnosis and Classification of Cutaneous Neurofibromass Neuro-oncology Advances. Jul, 2020 | Pubmed ID: 32642737 Serum Pro-BDNF Levels Correlate with Phospho-tau Staining in Alzheimer's Disease Neurobiology of Aging. 03, 2020 | Pubmed ID: 31882186 Salinomycin Targets the Genome of Radioresistant Cells in Glioblastomas Neuro-oncology. 02, 2020 | Pubmed ID: 31784742 The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease Molecular & Cellular Proteomics : MCP. 01, 2020 | Pubmed ID: 31699905 Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia The American Journal of Pathology. 10, 2019 | Pubmed ID: 31351986 ErbB4 Promotes Malignant Peripheral Nerve Sheath Tumor Pathogenesis Via Ras-independent Mechanisms Cell Communication and Signaling : CCS. 07, 2019 | Pubmed ID: 31291965 The Evolution and Multi-molecular Properties of NF1 Cutaneous Neurofibromas Originating from C-fiber Sensory Endings and Terminal Schwann Cells at Normal Sites of Sensory Terminations in the Skin PloS One. 2019 | Pubmed ID: 31107888 Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia Journal of Neuropathology and Experimental Neurology. 04, 2019 | Pubmed ID: 30856249 Cutaneous Neurofibromas: Current Clinical and Pathologic Issues Neurology. 07, 2018 | Pubmed ID: 29987130 Oridonin Inhibits Aberrant AKT Activation in Breast Cancer Oncotarget. May, 2018 | Pubmed ID: 29844859 Pathology of NNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease Neuroscience. 08, 2018 | Pubmed ID: 29782905 Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms Advances in Anatomic Pathology. Sep, 2018 | Pubmed ID: 29762158 Rare Coding Variants in PLCG2, ABI3, and TREM2 Implicate Microglial-mediated Innate Immunity in Alzheimer's Disease Nature Genetics. 09, 2017 | Pubmed ID: 28714976 The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve Journal of Neuropathology and Experimental Neurology. 04, 2017 | Pubmed ID: 28340093 BH3 Mimetics Suppress CXCL12 Expression in Human Malignant Peripheral Nerve Sheath Tumor Cells Oncotarget. Jan, 2017 | Pubmed ID: 28055968 Neuronal Exosomes Reveal Alzheimer's Disease Biomarkers in Down Syndrome Alzheimer's & Dementia : the Journal of the Alzheimer's Association. May, 2017 | Pubmed ID: 27755974 Current Status and Recommendations for Biomarkers and Biobanking in Neurofibromatosis Neurology. Aug, 2016 | Pubmed ID: 27527649 STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells Molecular Cancer Research : MCR. 05, 2016 | Pubmed ID: 26883073 The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors As a Paradigm for Cross-Species Comparative Oncogenomics The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26740486 Classic Ras Proteins Promote Proliferation and Survival Via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells Journal of Neuropathology and Experimental Neurology. Jun, 2015 | Pubmed ID: 25946318 Combinatorial Therapy with Tamoxifen and Trifluoperazine Effectively Inhibits Malignant Peripheral Nerve Sheath Tumor Growth by Targeting Complementary Signaling Cascades Journal of Neuropathology and Experimental Neurology. Nov, 2014 | Pubmed ID: 25289889 Variantes Genéticas Comunes En Los Loci CLDN2 Y PRSS1-PRSS2 Alteran El Riesgo De Pancreatitis Relacionados Con El Alcohol Y Esporádica Nature Genetics. Nov, 2012 | Pubmed ID: 23143602 El Pan ErbB Inhibidor PD168393 Mejora La Disfunción Lisosomal Inducida Por La Muerte Apoptótica En Células Malignas De Nervios Periféricos Tumor De La Vaina Neuro-oncology. Jan, 2012 | Pubmed ID: 22259051 Mecanismos Moleculares De Promoción De La Patogénesis De Neoplasias De Células De Schwann Acta Neuropathologica. Dec, 2011 | Pubmed ID: 22160322 Los Modelos De Ratón Modificados Genéticamente Arrojar Nueva Luz Sobre La Patogénesis De La Neurofibromatosis Tipo I Relacionados Con Neoplasias Del Sistema Nervioso Periférico Brain Research Bulletin. Aug, 2011 | Pubmed ID: 21855613 Variantes Comunes En MS4A4/MS4A6E, CD2AP, CD33 Y EPHA1 Se Asocian Con Enfermedades De Aparición Tardía De Alzheimer Nature Genetics. May, 2011 | Pubmed ID: 21460841 El Tamoxifeno Inhibe Maligno Vaina De Nervio Periférico El Crecimiento Del Tumor En Un Receptor De Estrógeno De Manera Independiente Neuro-oncology. Jan, 2011 | Pubmed ID: 21075781 Variantes Comunes En 7p21 Están Asociadas Con La Degeneración Lobar Frontotemporal Con TDP-43 Inclusiones Nature Genetics. Mar, 2010 | Pubmed ID: 20154673 Neuregulin-1 Beta and Neuregulin-1 Alpha Differentially Affect the Migration and Invasion of Malignant Peripheral Nerve Sheath Tumor Cells Glia. Nov, 2009 | Pubmed ID: 19306381 ¿Cómo Las Células De Schwann Forman Tumores De Linaje En La NF1? Glia. Nov, 2008 | Pubmed ID: 18803326 Diferencial De Activación De C-fos Y La Caspasa-3 En Las Subpoblaciones De Neuronas En Hipocampo Después De Hipoxia-isquemia Neonatal Journal of Neuroscience Research. Apr, 2008 | Pubmed ID: 18030677 BH3-sólo Se Pro-apoptóticos Bcl-2 Miembros De La Familia Noxa Y Puma Mediate Muerte Neuronal Precursor De La Célula The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2006 | Pubmed ID: 16822983 Interacciones Entre La Beta-neuregulina Y Neurotrofinas En La Apoptosis De Las Neuronas Motoras Journal of Neurochemistry. Apr, 2006 | Pubmed ID: 16524373 Factores Neuregulin Crecimiento Y Sus Receptores ErbB Formar Una Red De Señalización Potencial Para La Tumorigénesis Schwannoma Journal of Neuropathology and Experimental Neurology. Feb, 2006 | Pubmed ID: 16462207 La Activación De La Vía De Señalización Neuregulin-1/ErbB Promueve La Proliferación De Células De Schwann Neoplásicas Malignas En Humanos Vaina Nerviosa Periférica Tumores Oncogene. Aug, 2005 | Pubmed ID: 15897877 Neuregulin-1 Aumenta La Supervivencia De Las Células De Glioma Humanos Astrocíticos Glia. Aug, 2005 | Pubmed ID: 15812817 Mutaciones Supresoras Tumorales Y Factor De Crecimiento De Señalización En La Patogénesis De La NF1 Asociados a Los Tumores De Vaina Nerviosa Periférica: II. El Papel De La Señalización Del Factor De Crecimiento Desregulada Journal of Neuropathology and Experimental Neurology. Jan, 2005 | Pubmed ID: 15715079 Entrega Gene Mejorada En Células De La Neuroglia El Uso De Un Vector De Adenovirus Modificado Con Fibra Biochemical and Biophysical Research Communications. Mar, 2005 | Pubmed ID: 15708001 Específicas Del Ganglio-Los Patrones De La Diabetes Modulada Expresión Génica Se Establecen En Los Ganglios Simpáticos Prevertebral Y Paravertebral Antes Del Desarrollo De La Distrofia Neuroaxonal Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581182 Mutaciones Supresoras Tumorales Y Factor De Crecimiento De Señalización En La Patogénesis De La NF1 Asociados a Los Tumores De Vaina Nerviosa Periférica. I. El Papel De Las Mutaciones Supresoras Tumorales Journal of Neuropathology and Experimental Neurology. Nov, 2004 | Pubmed ID: 15581179 Neuregulin-1b Induce La Extensión De Las Neuritas Y Arborización En Cultivos De Neuronas Del Hipocampo Molecular and Cellular Neurosciences. Dec, 2004 | Pubmed ID: 15555917 Receptores ErbB Tirosina Quinasa Transmembrana Se Expresan En Neuronas Sensoriales Y Motoras Se Proyectan Dentro Del Nervio Ciático The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2004 | Pubmed ID: 15385576 La Activación Constitutiva De La Vía De Señalización Neuregulin-1/erbB Promueve La Proliferación De Una Línea Periférica De La Célula Humana Neuroepitelioma Journal of Neuro-oncology. Feb, 2004 | Pubmed ID: 15015657 Las Neuropatías Hipertróficas Y Los Tumores Malignos De Vaina Nerviosa Periférica En Ratones Transgénicos Que Sobreexpresan El Crecimiento Glial Beta3 Factor En Myelinating Células De Schwann The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12917360 Activación Constitutiva De La Vía De Señalización Del Receptor De Neuregulin-1/ErbB Es Esencial Para La Proliferación De Una Línea De Células De Schwann Neoplásicas Glia. Aug, 2003 | Pubmed ID: 12838503 Ácido Lisofosfatídico Promueve La Proliferación De Células De Schwann Aisladas De Adultos a Partir Del Nervio Ciático Axotomizado Journal of Neuropathology and Experimental Neurology. May, 2003 | Pubmed ID: 12769191 Neuregulin-1 Aumenta La Motilidad Y La Migración De Las Células De Glioma Humanos Astrocíticos The Journal of Biological Chemistry. Jun, 2003 | Pubmed ID: 12600989 Inmunorreactividad Neuregulin-1 Y ErbB4 Se Asocia Con Las Placas Neuríticas En El Cerebro De La Enfermedad De Alzheimer Y En Un Modelo Transgénico De La Enfermedad De Alzheimer Journal of Neuropathology and Experimental Neurology. Jan, 2003 | Pubmed ID: 12528817 Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Cancer Research Definición de las funciones genéticas en la tumorigénesis mediante la ablación ex vivo de alelos floxados en células tumorales malignas de la vaina del nervio periférico Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Cancer Research Xenotrasplante ortotópico de los Derechos Humanos-luciferasa Tagged células malignas del tumor vaina de nervio periférico para In vivo Pruebas de candidatos a agentes terapéuticos Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicine
Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens (Video) | JoVE Brittany Turner-Ivey1, Jody Fromm Longo2, Dorea P. Jenkins2, Stephen T. Guest3, Steven L. Carroll1,2 1Hollings Cancer Center, Medical University of South Carolina, 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 3Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor JoVE 65430 Cancer Research
Definición de las funciones genéticas en la tumorigénesis mediante la ablación ex vivo de alelos floxados en células tumorales malignas de la vaina del nervio periférico Jody Fromm Longo1, Stephanie N. Brosius2,3, Steven L. Carroll1 1Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 2Department of Pediatrics and Neurology, Perelman School of Medicine of the University of Pennsylvania, 3Division of Child Neurology, Children's Hospital of Philadelphia JoVE 62740 Cancer Research
Xenotrasplante ortotópico de los Derechos Humanos-luciferasa Tagged células malignas del tumor vaina de nervio periférico para In vivo Pruebas de candidatos a agentes terapéuticos Amy N. Turk1, Stephanie J. Byer1, Kurt R. Zinn2, Steven L. Carroll1,3 1Department of Pathology, University of Alabama at Birmingham - UAB, 2Department of Radiology, University of Alabama at Birmingham - UAB, 3Department of Cell Biology and Neurobiology, University of Alabama at Birmingham - UAB JoVE 2558 Medicine
