Thomas E. Lane Pathology University of Utah Biography Publications Institution JoVE Articles Thomas E. Lane has not added a biography. If you are Thomas E. Lane and would like to personalize this page please email our Author Liaison for assistance. Publications Complementary Roles of Fas-associated Death Domain (FADD) and Receptor Interacting Protein Kinase-3 (RIPK3) in T-cell Homeostasis and Antiviral Immunity Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21876153 CXCR4 Signaling Regulates Remyelination by Endogenous Oligodendrocyte Progenitor Cells in a Viral Model of Demyelination Glia. Aug, 2011 | Pubmed ID: 21830237 Importance of the CCR5-CCL5 Axis for Mucosal Trypanosoma Cruzi Protection and B Cell Activation Journal of Immunology (Baltimore, Md. : 1950). Aug, 2011 | Pubmed ID: 21715689 CXCR2 Signaling Protects Oligodendrocyte Progenitor Cells from IFN-γ/CXCL10-mediated Apoptosis Glia. Oct, 2011 | Pubmed ID: 21656856 Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice The American Journal of Pathology. Jun, 2011 | Pubmed ID: 21531375 G-CSF-mediated Thrombopoietin Release Triggers Neutrophil Motility and Mobilization from Bone Marrow Via Induction of Cxcr2 Ligands Blood. Apr, 2011 | Pubmed ID: 21224471 Impaired Immune Responses Following Spinal Cord Injury Lead to Reduced Ability to Control Viral Infection Experimental Neurology. Nov, 2010 | Pubmed ID: 20832407 The Role of Chemokines During Viral Infection of the CNS PLoS Pathogens. 2010 | Pubmed ID: 20686655 Chronic Systemic Infection Exacerbates Ischemic Brain Damage Via a CCL5 (regulated on Activation, Normal T-cell Expressed and Secreted)-mediated Proinflammatory Response in Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2010 | Pubmed ID: 20668193 Cell Replacement Therapies to Promote Remyelination in a Viral Model of Demyelination Journal of Neuroimmunology. Jul, 2010 | Pubmed ID: 20627412 Myelin Repair is Accelerated by Inactivating CXCR2 on Nonhematopoietic Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2010 | Pubmed ID: 20610741 CXCR2 Signaling Protects Oligodendrocytes and Restricts Demyelination in a Mouse Model of Viral-induced Demyelination PloS One. 2010 | Pubmed ID: 20596532 Migration of Engrafted Neural Stem Cells is Mediated by CXCL12 Signaling Through CXCR4 in a Viral Model of Multiple Sclerosis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534452 The Pathogenesis of Murine Coronavirus Infection of the Central Nervous System Critical Reviews in Immunology. 2010 | Pubmed ID: 20370625 CXCR2-positive Neutrophils Are Essential for Cuprizone-induced Demyelination: Relevance to Multiple Sclerosis Nature Neuroscience. Mar, 2010 | Pubmed ID: 20154684 The Biology of Persistent Infection: Inflammation and Demyelination Following Murine Coronavirus Infection of the Central Nervous System Current Immunology Reviews. May, 2009 | Pubmed ID: 19946572 A Protective Role for ELR+ Chemokines During Acute Viral Encephalomyelitis PLoS Pathogens. Nov, 2009 | Pubmed ID: 19893623 CXCL10 and Trafficking of Virus-specific T Cells During Coronavirus-induced Demyelination Autoimmunity. Sep, 2009 | Pubmed ID: 19626487 Cutting Edge: the Chemokine Receptor CXCR3 Retains Invariant NK T Cells in the Thymus Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009 | Pubmed ID: 19620294 Endogenous Remyelination is Induced by Transplant Rejection in a Viral Model of Multiple Sclerosis Journal of Neuroimmunology. Jul, 2009 | Pubmed ID: 19477025 IFN-gamma-mediated Suppression of Coronavirus Replication in Glial-committed Progenitor Cells Virology. Feb, 2009 | Pubmed ID: 19059617 Insertion of the CXC Chemokine Ligand 9 (CXCL9) into the Mouse Hepatitis Virus Genome Results in Protection from Viral-induced Encephalitis and Hepatitis Virology. Dec, 2008 | Pubmed ID: 18973912 CXCL10/CXCR3-mediated Responses Promote Immunity to Respiratory Syncytial Virus Infection by Augmenting Dendritic Cell and CD8(+) T Cell Efficacy European Journal of Immunology. Aug, 2008 | Pubmed ID: 18624292 Generation of a Protective T-cell Response Following Coronavirus Infection of the Central Nervous System is Not Dependent on IL-12/23 Signaling Viral Immunology. Jun, 2008 | Pubmed ID: 18570589 Mouse Hepatitis Virus Infection of the CNS: a Model for Defense, Disease, and Repair Frontiers in Bioscience : a Journal and Virtual Library. 2008 | Pubmed ID: 18508518 The Th17-ELR+ CXC Chemokine Pathway is Essential for the Development of Central Nervous System Autoimmune Disease The Journal of Experimental Medicine. Apr, 2008 | Pubmed ID: 18347102 NKG2D Receptor Signaling Enhances Cytolytic Activity by Virus-specific CD8+ T Cells: Evidence for a Protective Role in Virus-induced Encephalitis Journal of Virology. Mar, 2008 | Pubmed ID: 18160433 Evidence for Differential Roles for NKG2D Receptor Signaling in Innate Host Defense Against Coronavirus-induced Neurological and Liver Disease Journal of Virology. Mar, 2008 | Pubmed ID: 18094157 CCR1 Deficiency Increases Susceptibility to Fatal Coronavirus Infection of the Central Nervous System Viral Immunology. Dec, 2007 | Pubmed ID: 18158733 DRAK2 Regulates Memory T Cell Responses Following Murine Coronavirus Infection Autoimmunity. Nov, 2007 | Pubmed ID: 17966037 Therapeutic Neutralization of CXCL10 Decreases Secondary Degeneration and Functional Deficit After Spinal Cord Injury in Mice Regenerative Medicine. Sep, 2007 | Pubmed ID: 17907930 Expression of CXC Chemokine Ligand 10 from the Mouse Hepatitis Virus Genome Results in Protection from Viral-induced Neurological and Liver Disease Journal of Immunology (Baltimore, Md. : 1950). Jul, 2007 | Pubmed ID: 17617609 Anti-viral Effector T Cell Responses and Trafficking Are Not Dependent Upon DRAK2 Signaling Following Viral Infection of the Central Nervous System Autoimmunity. Feb, 2007 | Pubmed ID: 17364498 T-cell Function is Partially Maintained in the Absence of Class IA Phosphoinositide 3-kinase Signaling Blood. Apr, 2007 | Pubmed ID: 17164340 T Cell Antiviral Effector Function is Not Dependent on CXCL10 Following Murine Coronavirus Infection Journal of Immunology (Baltimore, Md. : 1950). Dec, 2006 | Pubmed ID: 17142734 Sjögren's Syndrome-like Disease in Mice with T Cells Lacking Class 1A Phosphoinositide-3-kinase Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17071741 NKG2D Signaling and Host Defense After Mouse Hepatitis Virus Infection of the Central Nervous System Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17037561 Dengue Virus Induces Expression of CXC Chemokine Ligand 10/IFN-gamma-inducible Protein 10, Which Competitively Inhibits Viral Binding to Cell Surface Heparan Sulfate Journal of Immunology (Baltimore, Md. : 1950). Sep, 2006 | Pubmed ID: 16920957 Chemokine CC Receptor 2 is Important for Acute Control of Cardiac Parasitism but Does Not Contribute to Cardiac Inflammation After Infection with Trypanosoma Cruzi The Journal of Infectious Diseases. Jun, 2006 | Pubmed ID: 16652288 Differential Roles for CXCR3 in CD4+ and CD8+ T Cell Trafficking Following Viral Infection of the CNS European Journal of Immunology. Mar, 2006 | Pubmed ID: 16479546 Abnormal Immune Response of CCR5-deficient Mice to Ocular Infection with Herpes Simplex Virus Type 1 The Journal of General Virology. Mar, 2006 | Pubmed ID: 16476970 Coronavirus Infection of the Central Nervous System: Host-virus Stand-off Nature Reviews. Microbiology. Feb, 2006 | Pubmed ID: 16415928 The CC Chemokine Receptor 5 is Important in Control of Parasite Replication and Acute Cardiac Inflammation Following Infection with Trypanosoma Cruzi Infection and Immunity. Jan, 2006 | Pubmed ID: 16368966 The Chemokines CXCL9 and CXCL10 Promote a Protective Immune Response but Do Not Contribute to Cardiac Inflammation Following Infection with Trypanosoma Cruzi Infection and Immunity. Jan, 2006 | Pubmed ID: 16368965 Transplantation of Glial-committed Progenitor Cells into a Viral Model of Multiple Sclerosis Induces Remyelination in the Absence of an Attenuated Inflammatory Response Experimental Neurology. Feb, 2006 | Pubmed ID: 16297915 Accelerated Intestinal Epithelial Cell Turnover: a New Mechanism of Parasite Expulsion Science (New York, N.Y.). Jun, 2005 | Pubmed ID: 15933199 Neutralization of Chemokines RANTES and MIG Increases Virus Antigen Expression and Spinal Cord Pathology During Theiler's Virus Infection International Immunology. May, 2005 | Pubmed ID: 15824069 Differential Roles of CCL2 and CCR2 in Host Defense to Coronavirus Infection Virology. Nov, 2004 | Pubmed ID: 15518805 Consequences of CXCL10 and IL-6 Induction by the Murine IFN-alpha1 Transgene in Ocular Herpes Simplex Virus Type 1 Infection Immunologic Research. 2004 | Pubmed ID: 15477660 The CC Chemokine Ligand 3 Regulates CD11c+CD11b+CD8alpha- Dendritic Cell Maturation and Activation Following Viral Infection of the Central Nervous System: Implications for a Role in T Cell Activation Virology. Sep, 2004 | Pubmed ID: 15327893 Enhanced T Cell Proliferation in Mice Lacking the P85beta Subunit of Phosphoinositide 3-kinase Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15153476 Remyelination, Axonal Sparing, and Locomotor Recovery Following Transplantation of Glial-committed Progenitor Cells into the MHV Model of Multiple Sclerosis Experimental Neurology. Jun, 2004 | Pubmed ID: 15144852 Antibody Targeting of the CC Chemokine Ligand 5 Results in Diminished Leukocyte Infiltration into the Central Nervous System and Reduced Neurologic Disease in a Viral Model of Multiple Sclerosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2004 | Pubmed ID: 15034013 Distinct Roles for IP-10/CXCL10 in Three Animal Models, Theiler's Virus Infection, EAE, and MHV Infection, for Multiple Sclerosis: Implication of Differing Roles for IP-10 Multiple Sclerosis (Houndmills, Basingstoke, England). Feb, 2004 | Pubmed ID: 14760949 CXC Chemokine Ligand 10 Controls Viral Infection in the Central Nervous System: Evidence for a Role in Innate Immune Response Through Recruitment and Activation of Natural Killer Cells Journal of Virology. Jan, 2004 | Pubmed ID: 14694090 Reducing Inflammation Decreases Secondary Degeneration and Functional Deficit After Spinal Cord Injury Experimental Neurology. Nov, 2003 | Pubmed ID: 14637115 Measles Virus Infection Induces Chemokine Synthesis by Neurons Journal of Immunology (Baltimore, Md. : 1950). Sep, 2003 | Pubmed ID: 12960336 Effect of Anti-CXCL10 Monoclonal Antibody on Herpes Simplex Virus Type 1 Keratitis and Retinal Infection Journal of Virology. Sep, 2003 | Pubmed ID: 12941914 Functional Analysis of the CC Chemokine Receptor 5 (CCR5) on Virus-specific CD8+ T Cells Following Coronavirus Infection of the Central Nervous System Virology. Aug, 2003 | Pubmed ID: 12919745 Adenovirus-mediated Expression of CXCL10 in the Central Nervous System Results in T-cell Recruitment and Limited Neuropathology Journal of Neurovirology. Jun, 2003 | Pubmed ID: 12775415 CC Chemokine Ligand 3 (CCL3) Regulates CD8(+)-T-cell Effector Function and Migration Following Viral Infection Journal of Virology. Apr, 2003 | Pubmed ID: 12634360 Functional Expression of Chemokine Receptor CCR5 on CD4(+) T Cells During Virus-induced Central Nervous System Disease Journal of Virology. Jan, 2003 | Pubmed ID: 12477824 Mouse Hepatitis Virus Infection of the Central Nervous System: Chemokine-mediated Regulation of Host Defense and Disease Viral Immunology. 2002 | Pubmed ID: 12081011 IFN-gamma-inducible Protein 10 (IP-10; CXCL10)-deficient Mice Reveal a Role for IP-10 in Effector T Cell Generation and Trafficking Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002 | Pubmed ID: 11907072 Lack of Nitric Oxide Synthase Type 2 (NOS2) Results in Reduced Neuronal Apoptosis and Mortality Following Mouse Hepatitis Virus Infection of the Central Nervous System Journal of Neurovirology. Feb, 2002 | Pubmed ID: 11847593 Два-Фотон изображений клеточной динамики в спинном мозге мыши Jason G. Weinger1, Milton L. Greenberg2, Melanie P. Matheu4, Ian Parker3, Craig M. Walsh1, Thomas E. Lane5, Michael D. Cahalan2 1Molecular Biology and Biochemistry, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine, 3Neurobiology and Behavior, University of California, Irvine, 4University of California San Francisco Diabetes Center, University of California, San Francisco, 5Pathology, University of Utah JoVE 52580 Neuroscience Хирургическое трансплантации Мышь нейронных стволовых клеток в спинной мозг мышей, инфицированных Нейротропные вируса гепатита мышь Kevin S. Carbajal1,2, Jason G. Weinger1,2, Lucia M. Whitman1,2, Chris S. Schaumburg1,2, Thomas E. Lane1,2,3 1Department of Molecular Biology and Biochemistry, University of California, Irvine, 2Sue and Bill Gross Stem Cell Center, University of California, Irvine, 3Institute for Immunology, University of California, Irvine JoVE 2834 Neuroscience
Два-Фотон изображений клеточной динамики в спинном мозге мыши Jason G. Weinger1, Milton L. Greenberg2, Melanie P. Matheu4, Ian Parker3, Craig M. Walsh1, Thomas E. Lane5, Michael D. Cahalan2 1Molecular Biology and Biochemistry, University of California, Irvine, 2Physiology and Biophysics, University of California, Irvine, 3Neurobiology and Behavior, University of California, Irvine, 4University of California San Francisco Diabetes Center, University of California, San Francisco, 5Pathology, University of Utah JoVE 52580 Neuroscience
Хирургическое трансплантации Мышь нейронных стволовых клеток в спинной мозг мышей, инфицированных Нейротропные вируса гепатита мышь Kevin S. Carbajal1,2, Jason G. Weinger1,2, Lucia M. Whitman1,2, Chris S. Schaumburg1,2, Thomas E. Lane1,2,3 1Department of Molecular Biology and Biochemistry, University of California, Irvine, 2Sue and Bill Gross Stem Cell Center, University of California, Irvine, 3Institute for Immunology, University of California, Irvine JoVE 2834 Neuroscience
