Thomas Foltynie Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery UCL Institute of Neurology Biography Publications Institution JoVE Articles Thomas Foltynie has not added a biography. If you are Thomas Foltynie and would like to personalize this page please email our Author Liaison for assistance. Publications Midline Frontal Cortex Low-frequency Activity Drives Subthalamic Nucleus Oscillations During Conflict The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2014 | Pubmed ID: 24849364 Long-term Outcome of Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease Using an MRI-guided and MRI-verified Approach Journal of Neurology, Neurosurgery, and Psychiatry. Apr, 2014 | Pubmed ID: 24790212 K27 Ubiquitination of the Mitochondrial Transport Protein Miro is Dependent on Serine 65 of the Parkin Ubiquitin Ligase The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24671417 Motor and Cognitive Advantages Persist 12 Months After Exenatide Exposure in Parkinson's Disease Journal of Parkinson's Disease. Mar, 2014 | Pubmed ID: 24662192 Exenatide As a Potential Treatment for Patients with Parkinson's Disease: First Steps into the Clinic Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Feb, 2014 | Pubmed ID: 24529524 Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease: Two Case Reports JAMA Neurology. Jan, 2014 | Pubmed ID: 24217017 Short and Long Term Outcome of Bilateral Pallidal Stimulation in Chorea-acanthocytosis PloS One. 2013 | Pubmed ID: 24223913 Phase Dependent Modulation of Tremor Amplitude in Essential Tremor Through Thalamic Stimulation Brain : a Journal of Neurology. Oct, 2013 | Pubmed ID: 24038075 The Nucleus Basalis of Meynert: a New Target for Deep Brain Stimulation in Dementia? Neuroscience and Biobehavioral Reviews. Dec, 2013 | Pubmed ID: 24035740 Subthalamic Nucleus Local Field Potential Activity During the Eriksen Flanker Task Reveals a Novel Role for Theta Phase During Conflict Monitoring The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2013 | Pubmed ID: 24027276 Dopamine Agonists Rather Than Deep Brain Stimulation Cause Reflection Impulsivity in Parkinson's Disease Journal of Parkinson's Disease. 2013 | Pubmed ID: 23938343 Pallidal Stimulation for Cervical Dystonia Does Not Correct Abnormal Temporal Discrimination Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2013 | Pubmed ID: 23853089 Adaptive Deep Brain Stimulation in Advanced Parkinson Disease Annals of Neurology. Sep, 2013 | Pubmed ID: 23852650 Commentary Movement Disorders : Official Journal of the Movement Disorder Society. Jun, 2013 | Pubmed ID: 23801561 The CamPaIGN Study of Parkinson's Disease: 10-year Outlook in an Incident Population-based Cohort Journal of Neurology, Neurosurgery, and Psychiatry. Nov, 2013 | Pubmed ID: 23781007 Complementary Roles of Different Oscillatory Activities in the Subthalamic Nucleus in Coding Motor Effort in Parkinsonism Experimental Neurology. Oct, 2013 | Pubmed ID: 23778147 Exenatide and the Treatment of Patients with Parkinson's Disease The Journal of Clinical Investigation. Jun, 2013 | Pubmed ID: 23728174 Image-guided and Image-verified Deep Brain Stimulation Movement Disorders : Official Journal of the Movement Disorder Society. Feb, 2013 | Pubmed ID: 23390009 The Risk of Hardware Infection in Deep Brain Stimulation Surgery is Greater at Impulse Generator Replacement Than at the Primary Procedure Stereotactic and Functional Neurosurgery. 2013 | Pubmed ID: 23207787 Frequency Specific Activity in Subthalamic Nucleus Correlates with Hand Bradykinesia in Parkinson's Disease Experimental Neurology. Feb, 2013 | Pubmed ID: 23178580 Deep Brain Stimulation As a Treatment for Chorea-acanthocytosis Journal of Neurology. Jan, 2013 | Pubmed ID: 23086180 Subthalamic Nucleus Gamma Oscillations Mediate a Switch from Automatic to Controlled Processing: a Study of Random Number Generation in Parkinson's Disease NeuroImage. Jan, 2013 | Pubmed ID: 22960249 Parkinson's Disease, Insulin Resistance and Novel Agents of Neuroprotection Brain : a Journal of Neurology. Feb, 2013 | Pubmed ID: 22344583 Image-verified Deep Brain Stimulation Reduces Risk and Cost with No Apparent Impact on Efficacy Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2012 | Pubmed ID: 23032691 Subthalamic Nucleus Activity Optimizes Maximal Effort Motor Responses in Parkinson's Disease Brain : a Journal of Neurology. Sep, 2012 | Pubmed ID: 22858550 Decision Making, Impulsivity, and Addictions: Do Parkinson's Disease Patients Jump to Conclusions? Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2012 | Pubmed ID: 22821557 Understanding and Prevention of "therapy-" Induced Dyskinesias Parkinson's Disease. 2012 | Pubmed ID: 22685687 Confirmation of Functional Zones Within the Human Subthalamic Nucleus: Patterns of Connectivity and Sub-parcellation Using Diffusion Weighted Imaging NeuroImage. Mar, 2012 | Pubmed ID: 22173294 Screening for VPS35 Mutations in Parkinson's Disease Neurobiology of Aging. Apr, 2012 | Pubmed ID: 22154191 Genetic and Pathological Links Between Parkinson's Disease and the Lysosomal Disorder Sanfilippo Syndrome Movement Disorders : Official Journal of the Movement Disorder Society. Feb, 2012 | Pubmed ID: 22102531 Reducing Hemorrhagic Complications in Functional Neurosurgery: a Large Case Series and Systematic Literature Review Journal of Neurosurgery. Jan, 2012 | Pubmed ID: 21905798 The Factor Structure of the UPDRS As an Index of Disease Progression in Parkinson's Disease Journal of Parkinson's Disease. 2011 | Pubmed ID: 23939258 Critical Aspects of Clinical Trial Design for Novel Cell and Gene Therapies Parkinson's Disease. 2011 | Pubmed ID: 22254150 Urinary Incontinence Following Deep Brain Stimulation of the Pedunculopontine Nucleus Acta Neurochirurgica. Dec, 2011 | Pubmed ID: 21927820 MRI-guided Subthalamic Nucleus Deep Brain Stimulation Without Microelectrode Recording: Can We Dispense with Surgery Under Local Anaesthesia? Stereotactic and Functional Neurosurgery. 2011 | Pubmed ID: 21921673 A Gamma Band Specific Role of the Subthalamic Nucleus in Switching During Verbal Fluency Tasks in Parkinson's Disease Experimental Neurology. Dec, 2011 | Pubmed ID: 21872587 Clinical Safety of Brain Magnetic Resonance Imaging with Implanted Deep Brain Stimulation Hardware: Large Case Series and Review of the Literature World Neurosurgery. Jul-Aug, 2011 | Pubmed ID: 21839969 Functional Imaging of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21674623 The Natural History of Treated Parkinson's Disease in an Incident, Community Based Cohort Journal of Neurology, Neurosurgery, and Psychiatry. Oct, 2011 | Pubmed ID: 21593513 Deep Brain Stimulation for Gilles De La Tourette Syndrome: a Case Series Targeting Subregions of the Globus Pallidus Internus Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2011 | Pubmed ID: 21538528 Skewering the Subthalamic Nucleus Via a Parietal Approach Stereotactic and Functional Neurosurgery. 2011 | Pubmed ID: 21293165 Gene Therapy: a Viable Therapeutic Strategy for Parkinson's Disease? Journal of Neurology. Feb, 2011 | Pubmed ID: 20963433 Improving Targeting in Image-guided Frame-based Deep Brain Stimulation Neurosurgery. Dec, 2010 | Pubmed ID: 21099570 Which Patients with Dystonia Benefit from Deep Brain Stimulation? A Metaregression of Individual Patient Outcomes Journal of Neurology, Neurosurgery, and Psychiatry. Dec, 2010 | Pubmed ID: 20841370 Minimizing Brain Shift in Stereotactic Functional Neurosurgery Neurosurgery. Sep, 2010 | Pubmed ID: 20679927 Surgical Management of Parkinson's Disease Expert Review of Neurotherapeutics. Jun, 2010 | Pubmed ID: 20518607 Association of the Human Leucocyte Antigen Region with Susceptibility to Parkinson's Disease Journal of Neurology, Neurosurgery, and Psychiatry. Aug, 2010 | Pubmed ID: 20462916 The Distinct Cognitive Syndromes of Parkinson's Disease: 5 Year Follow-up of the CamPaIGN Cohort Brain : a Journal of Neurology. Nov, 2009 | Pubmed ID: 19812213 Early and Marked Benefit with GPi DBS for Lubag Syndrome Presenting with Rapidly Progressive Life-threatening Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2009 | Pubmed ID: 19514062 Apolipoprotein E Genotype As a Risk Factor for Susceptibility to and Dementia in Parkinson's Disease Journal of Neurology. Mar, 2009 | Pubmed ID: 19308307 No Evidence for Association Between an MAOA Functional Polymorphism and Susceptibility to Parkinson's Disease Journal of Neurology. Jan, 2009 | Pubmed ID: 19267171 Tau and Alpha-synuclein in Susceptibility To, and Dementia In, Parkinson's Disease Annals of Neurology. Aug, 2007 | Pubmed ID: 17683088 The Frequency and Validity of Self-reported Diagnosis of Parkinson's Disease in the UK Elderly: MRC CFAS Cohort BMC Neurology. 2006 | Pubmed ID: 16925826 Cognitive Deficits and Psychosis in Parkinson's Disease: a Review of Pathophysiology and Therapeutic Options CNS Drugs. 2006 | Pubmed ID: 16734499 No Alterations in Alpha-synuclein Gene Dosage Observed in Sporadic Parkinson's Disease Movement Disorders : Official Journal of the Movement Disorder Society. May, 2006 | Pubmed ID: 16552758 UCHL-1 is Not a Parkinson's Disease Susceptibility Gene Annals of Neurology. Apr, 2006 | Pubmed ID: 16450370 Mitochondrial DNA Haplogroup Cluster UKJT Reduces the Risk of PD Annals of Neurology. Apr, 2005 | Pubmed ID: 15786469 The BDNF Val66Met Polymorphism Has a Gender Specific Influence on Planning Ability in Parkinson's Disease Journal of Neurology. Jul, 2005 | Pubmed ID: 15772739 A Genome Wide Linkage Disequilibrium Screen in Parkinson's Disease Journal of Neurology. May, 2005 | Pubmed ID: 15726250 Planning Ability in Parkinson's Disease is Influenced by the COMT Val158met Polymorphism Movement Disorders : Official Journal of the Movement Disorder Society. Aug, 2004 | Pubmed ID: 15300652 The Future Challenges in Parkinson's Disease Journal of Neurology. Mar, 2004 | Pubmed ID: 15015024 The Cognitive Ability of an Incident Cohort of Parkinson's Patients in the UK. The CamPaIGN Study Brain : a Journal of Neurology. Mar, 2004 | Pubmed ID: 14691062 A Whole Genome Association Study in Multiple Sclerosis Patients from North Portugal Journal of Neuroimmunology. Oct, 2003 | Pubmed ID: 14575927 A Genome-wide Screen for Association in Hungarian Multiple Sclerosis Journal of Neuroimmunology. Oct, 2003 | Pubmed ID: 14575920 The Heterogeneity of Idiopathic Parkinson's Disease Journal of Neurology. Feb, 2002 | Pubmed ID: 11985378 Vascular Parkinsonism: a Review of the Precision and Frequency of the Diagnosis Neuroepidemiology. Jan-Feb, 2002 | Pubmed ID: 11744819 Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation Simon Little1, Alek Pogosyan1, Spencer Neal2, Ludvic Zrinzo2, Marwan Hariz2, Thomas Foltynie2, Patricia Limousin2, Peter Brown1 1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology JoVE 51403 Medicine
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation Simon Little1, Alek Pogosyan1, Spencer Neal2, Ludvic Zrinzo2, Marwan Hariz2, Thomas Foltynie2, Patricia Limousin2, Peter Brown1 1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery, UCL Institute of Neurology JoVE 51403 Medicine