Tim Spelman Department of Neurology Royal Melbourne Hospital Biography Publications Institution JoVE Articles Tim Spelman has not added a biography. If you are Tim Spelman and would like to personalize this page please email our Author Liaison for assistance. Publications 2015 - a Seminal Year for HIV Biomedical Prevention Journal of the International AIDS Society. 2015 | Pubmed ID: 26632479 Comparison of Oncological and Health Related Quality of Life (HRQOL) Outcomes Between Open (ORP) and Robotic-assisted Radical Prostatectomy (RARP) for Localized Prostate Cancer - Findings from the Population-based Victorian Prostate Cancer Registry (PCR) BJU International. Nov, 2015 | Pubmed ID: 26573954 Predictors and Rate of Adjuvant Radiation Therapy Following Radical Prostatectomy: A Report from the Prostate Cancer Registry Journal of Medical Imaging and Radiation Oncology. Nov, 2015 | Pubmed ID: 26548940 Response to Letter Journal of Travel Medicine. Nov, 2015 | Pubmed ID: 26503097 Which Factors Influence the Activity Levels of Individuals with Traumatic Brain Injury when They Are First Discharged Home from Hospital? Brain Injury. Sep, 2015 | Pubmed ID: 26399973 Defining Reliable Disability Outcomes in Multiple Sclerosis Brain : a Journal of Neurology. Nov, 2015 | Pubmed ID: 26359291 The Effect of Oral Immunomodulatory Therapy on Treatment Uptake and Persistence in Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Jul, 2015 | Pubmed ID: 26199347 Injecting Risk Behaviours Following Treatment for Hepatitis C Virus Infection Among People Who Inject Drugs: The Australian Trial in Acute Hepatitis C The International Journal on Drug Policy. Oct, 2015 | Pubmed ID: 26115881 Risks, Severity and Timing of Infections in Patients with Multiple Myeloma: a Longitudinal Cohort Study in the Era of Immunomodulatory Drug Therapy British Journal of Haematology. Oct, 2015 | Pubmed ID: 26105211 Central Line-associated Bloodstream Infections in Australian Intensive Care Units: Time-trends in Infection Rates, Etiology, and Antimicrobial Resistance Using a Comprehensive Victorian Surveillance Program, 2009-2013 American Journal of Infection Control. Aug, 2015 | Pubmed ID: 26026826 Predictors of Disability Worsening in Clinically Isolated Syndrome Annals of Clinical and Translational Neurology. May, 2015 | Pubmed ID: 26000321 Factors Associated with Discussion of Sexual Activity and Contraception in Women with HIV The Journal of Family Planning and Reproductive Health Care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists. Apr, 2015 | Pubmed ID: 25900524 "Seek, Test, Treat" Lessons From Australia: A Study of HIV Testing Patterns From a Cohort of Men Who Have Sex With Men Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2015 | Pubmed ID: 25835608 Diminishing Surgical Site Infections in Australia: Time Trends in Infection Rates, Pathogens and Antimicrobial Resistance Using a Comprehensive Victorian Surveillance Program, 2002-2013 Infection Control and Hospital Epidemiology. Apr, 2015 | Pubmed ID: 25782895 Comparison of Switch to Fingolimod or Interferon Beta/glatiramer Acetate in Active Multiple Sclerosis JAMA Neurology. Apr, 2015 | Pubmed ID: 25665031 Time of Day and Day of Week Trends in EMS Demand Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors. Jul-Sep, 2015 | Pubmed ID: 25664379 The CD14 C-260T Single Nucleotide Polymorphism (SNP) Modulates Monocyte/macrophage Activation in Treated HIV-infected Individuals Journal of Translational Medicine. 2015 | Pubmed ID: 25622527 Immediate Recall of Health Issues Discussed During a Pre-travel Consultation Journal of Travel Medicine. May-Jun, 2015 | Pubmed ID: 25594824 Switch to Natalizumab Versus Fingolimod in Active Relapsing-remitting Multiple Sclerosis Annals of Neurology. Mar, 2015 | Pubmed ID: 25546031 Clinical and Virological Predictors of Hepatic Flares in Pregnant Women with Chronic Hepatitis B Gut. Nov, 2015 | Pubmed ID: 25431458 Higher Human T-lymphotropic Virus Type 1 Subtype C Proviral Loads Are Associated with Bronchiectasis in Indigenous Australians: Results of a Case-control Study Open Forum Infectious Diseases. Mar, 2014 | Pubmed ID: 25734096 C-reactive Protein As a Predictor of Cardiovascular Risk in HIV-infected Individuals Sexual Health. Dec, 2014 | Pubmed ID: 25435195 Activation of HIV Transcription with Short-course Vorinostat in HIV-infected Patients on Suppressive Antiretroviral Therapy PLoS Pathogens. Oct, 2014 | Pubmed ID: 25393648 Seasonal Variation of Relapse Rate in Multiple Sclerosis is Latitude Dependent Annals of Neurology. Dec, 2014 | Pubmed ID: 25283272 A Major Reduction in Hospital-onset Staphylococcus Aureus Bacteremia in Australia: a Question of Definition Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Dec, 2014 | Pubmed ID: 25210018 Lytic Gene Expression is Frequent in HSV-1 Latent Infection and Correlates with the Engagement of a Cell-intrinsic Transcriptional Response PLoS Pathogens. Jul, 2014 | Pubmed ID: 25058429 Staphylococcus Aureus Bloodstream Infection in Australian Hospitals: Findings from a Victorian Surveillance System The Medical Journal of Australia. Mar, 2014 | Pubmed ID: 24641154 Lipopolysaccharide, Immune Activation, and Liver Abnormalities in HIV/hepatitis B Virus (HBV)-coinfected Individuals Receiving HBV-active Combination Antiretroviral Therapy The Journal of Infectious Diseases. Sep, 2014 | Pubmed ID: 24585898 Clinical Associations of Human T-Lymphotropic Virus Type 1 Infection in an Indigenous Australian Population PLoS Neglected Tropical Diseases. 2014 | Pubmed ID: 24454973 Associations Between Surface Markers on Blood Monocytes and Carotid Atherosclerosis in HIV-positive Individuals Immunology and Cell Biology. Feb, 2014 | Pubmed ID: 24296810 Positive Surgical Margins: Rate, Contributing Factors and Impact on Further Treatment: Findings from the Prostate Cancer Registry BJU International. Nov, 2014 | Pubmed ID: 24128010 Predictors and Dynamics of Postpartum Relapses in Women with Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2014 | Pubmed ID: 24107309 High Rates of Hepatitis C Virus Reinfection and Spontaneous Clearance of Reinfection in People Who Inject Drugs: a Prospective Cohort Study PloS One. 2013 | Pubmed ID: 24244654 Predictors of Raised Viral Load During Antiretroviral Therapy in Patients with and Without Prior Antiretroviral Use: a Cross-sectional Study PloS One. 2013 | Pubmed ID: 23967207 Impact of HIV-associated Conditions on Mortality in People Commencing Anti-retroviral Therapy in Resource Limited Settings PloS One. 2013 | Pubmed ID: 23935870 Chemokine Levels and Chemokine Receptor Expression in the Blood and the Cerebrospinal Fluid of HIV-infected Patients with Cryptococcal Meningitis and Cryptococcosis-associated Immune Reconstitution Inflammatory Syndrome The Journal of Infectious Diseases. Nov, 2013 | Pubmed ID: 23908492 Cryptococcosis-IRIS is Associated with Lower Cryptococcus-specific IFN-γ Responses Before Antiretroviral Therapy but Not Higher T-cell Responses During Therapy The Journal of Infectious Diseases. Sep, 2013 | Pubmed ID: 23766525 The Australian Multiple Sclerosis (MS) Immunotherapy Study: a Prospective, Multicentre Study of Drug Utilisation Using the MSBase Platform PloS One. 2013 | Pubmed ID: 23527252 Clinical and Mycological Predictors of Cryptococcosis-associated Immune Reconstitution Inflammatory Syndrome AIDS (London, England). Aug, 2013 | Pubmed ID: 23525034 Inhibition of Telomerase Activity by Human Immunodeficiency Virus (HIV) Nucleos(t)ide Reverse Transcriptase Inhibitors: a Potential Factor Contributing to HIV-associated Accelerated Aging The Journal of Infectious Diseases. Apr, 2013 | Pubmed ID: 23303810 Self-discharge by Adult Aboriginal Patients at Alice Springs Hospital, Central Australia: Insights from a Prospective Cohort Study Australian Health Review : a Publication of the Australian Hospital Association. May, 2013 | Pubmed ID: 23257238 Incidence of WHO Stage 3 and 4 Conditions Following Initiation of Anti-retroviral Therapy in Resource Limited Settings PloS One. 2012 | Pubmed ID: 23284857 Induction of Multi-functional T Cells in a Phase I Clinical Trial of Dendritic Cell Immunotherapy in Hepatitis C Virus Infected Individuals PloS One. 2012 | Pubmed ID: 22905088 An Automated CPR Device Compared with Standard Chest Compressions for Out-of-hospital Resuscitation BMC Emergency Medicine. 2012 | Pubmed ID: 22734854 Splenectomy Sequelae: an Analysis of Infectious Outcomes Among Adults in Victoria The Medical Journal of Australia. May, 2012 | Pubmed ID: 22621150 Prevalence Survey of Dermatological Conditions in Mountainous North India International Journal of Dermatology. May, 2012 | Pubmed ID: 22515583 Wind-driven Roof Turbines: a Novel Way to Improve Ventilation for TB Infection Control in Health Facilities PloS One. 2012 | Pubmed ID: 22253742 Similar Mortality and Reduced Loss to Follow-up in Integrated Compared with Vertical Programs Providing Antiretroviral Treatment in Sub-saharan Africa Journal of Acquired Immune Deficiency Syndromes (1999). Apr, 2012 | Pubmed ID: 22134144 Bronchiectasis is Associated with Human T-lymphotropic Virus 1 Infection in an Indigenous Australian Population Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jan, 2012 | Pubmed ID: 22095566 Comparative Clinical Effectiveness of Prophylactic Voriconazole/posaconazole to Fluconazole/itraconazole in Patients with Acute Myeloid Leukemia/myelodysplastic Syndrome Undergoing Cytotoxic Chemotherapy over a 12-year Period Haematologica. Mar, 2012 | Pubmed ID: 22058198 Medication Chart Intervention Improves Inpatient Thromboembolism Prophylaxis Chest. Mar, 2012 | Pubmed ID: 21778254 SPL7013 Gel (VivaGel®) Retains Potent HIV-1 and HSV-2 Inhibitory Activity Following Vaginal Administration in Humans PloS One. 2011 | Pubmed ID: 21935377 Intrahousehold Transmission of Pandemic (H1N1) 2009 Virus, Victoria, Australia Emerging Infectious Diseases. Sep, 2011 | Pubmed ID: 21888784 Sexual History Taking and Sexually Transmissible Infection Screening Practices Among Men Who Have Sex with Men: a Survey of Victorian General Practitioners Sexual Health. Sep, 2011 | Pubmed ID: 21851775 Risk Factors for HIV Seroconversion in Men Who Have Sex with Men in Victoria, Australia: Results from a Sentinel Surveillance System Sexual Health. Sep, 2011 | Pubmed ID: 21851771 Clinical Predictors of Immune Reconstitution Following Combination Antiretroviral Therapy in Patients from the Australian HIV Observational Database PloS One. 2011 | Pubmed ID: 21674057 Impact Evaluation of a Youth Sexually Transmissible Infection Awareness Campaign Using Routinely Collected Data Sources Sexual Health. Jun, 2011 | Pubmed ID: 21592439 Attributable Hospital Cost and Antifungal Treatment of Invasive Fungal Diseases in High-risk Hematology Patients: an Economic Modeling Approach Antimicrobial Agents and Chemotherapy. May, 2011 | Pubmed ID: 21357302 Determining the Impact of Text Messaging for Sexual Health Promotion to Young People Sexually Transmitted Diseases. Apr, 2011 | Pubmed ID: 20966830 Biological Determinants of Immune Reconstitution in HIV-infected Patients Receiving Antiretroviral Therapy: the Role of Interleukin 7 and Interleukin 7 Receptor α and Microbial Translocation The Journal of Infectious Diseases. Oct, 2010 | Pubmed ID: 20812848 HBV Mutations in Untreated HIV-HBV Co-infection Using Genomic Length Sequencing Virology. Sep, 2010 | Pubmed ID: 20655563 Early Adherence to Antiretroviral Medication As a Predictor of Long-term HIV Virological Suppression: Five-year Follow Up of an Observational Cohort PloS One. 2010 | Pubmed ID: 20485480 Surveillance of Drug Use Among Young People Attending a Music Festival in Australia, 2005-2008 Drug and Alcohol Review. Mar, 2010 | Pubmed ID: 20447222 Enhancement of Human Immunodeficiency Virus Type 1 Replication is Not Intrinsic to All Polyanion-based Microbicides Antimicrobial Agents and Chemotherapy. Aug, 2009 | Pubmed ID: 19528284 Enhanced Case Detection for Newly Acquired Hepatitis C Infection: Epidemiological Findings and Health Service Implications Communicable Diseases Intelligence Quarterly Report. Jun, 2008 | Pubmed ID: 18767425 A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data Tim Spelman1,2, Orla Gray3, Robyn Lucas4, Helmut Butzkueven1,2 1Department of Neurology, Royal Melbourne Hospital, 2Department of Medicine (RMH), The University of Melbourne, 3Department of Neurology, Ulster Hospital, 4National Centre for Epidemiology and Population Health, Australian National University JoVE 53169 Medicine
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data Tim Spelman1,2, Orla Gray3, Robyn Lucas4, Helmut Butzkueven1,2 1Department of Neurology, Royal Melbourne Hospital, 2Department of Medicine (RMH), The University of Melbourne, 3Department of Neurology, Ulster Hospital, 4National Centre for Epidemiology and Population Health, Australian National University JoVE 53169 Medicine