Ton J. Rabelink Department of Internal Medicine - Nephrology Leiden University Medical Center Biography Publications Institution JoVE Articles Ton J. Rabelink has not added a biography. If you are Ton J. Rabelink and would like to personalize this page please email our Author Liaison for assistance. Publications Preliminary Assessment of Safety and Tolerability of Avacopan During the Early Access Program for ANCA-Associated Vasculitis Biologics : Targets & Therapy. 2023 | Pubmed ID: 36721867 Inhibition of Complement Activation by CD55 Overexpression in Human Induced Pluripotent Stem Cell Derived Kidney Organoids Frontiers in Immunology. 2022 | Pubmed ID: 36713440 Ethnic Differences in Urinary Monocyte Chemoattractant Protein-1 and Heparanase-1 Levels in Individuals with Type 2 Diabetes: the HELIUS Study BMJ Open Diabetes Research & Care. Dec, 2022 | Pubmed ID: 36564084 Efficacy of Belimumab Combined with Rituximab in Severe Systemic Lupus Erythematosus: Study Protocol for the Phase 3, Multicenter, Randomized, Open-label Synbiose 2 Trial Trials. Nov, 2022 | Pubmed ID: 36371234 Spatial Dynamic Metabolomics Identifies Metabolic Cell Fate Trajectories in Human Kidney Differentiation Cell Stem Cell. Nov, 2022 | Pubmed ID: 36332571 Development of Central Venous Stenosis Upon ICD Implantation in Dialysis Patients: A Non-Negligible Issue Cardiology and Cardiovascular Medicine. Apr, 2022 | Pubmed ID: 36016586 Analyzing Cell-type-specific Dynamics of Metabolism in Kidney Repair Nature Metabolism. Sep, 2022 | Pubmed ID: 36008550 Vasculogenesis in Kidney Organoids Upon Transplantation NPJ Regenerative Medicine. Aug, 2022 | Pubmed ID: 35986027 COVID-box Experiences of Patients and Health Care Professionals (COVID-box Project): Single-Center, Retrospective, Observational Study JMIR Formative Research. Jul, 2022 | Pubmed ID: 35816688 Identifying Relevant Determinants of In-hospital Time to Diagnosis for ANCA-associated Vasculitis Patients Rheumatology Advances in Practice. 2022 | Pubmed ID: 35784016 Differential and Shared Genetic Effects on Kidney Function Between Diabetic and Non-diabetic Individuals Communications Biology. Jun, 2022 | Pubmed ID: 35697829 Toward Human Models of Cardiorenal Syndrome Frontiers in Cardiovascular Medicine. 2022 | Pubmed ID: 35694669 Large-scale Engineering of HiPSC-derived Nephron Sheets and Cryopreservation of Their Progenitors Stem Cell Research & Therapy. May, 2022 | Pubmed ID: 35578313 Heparan Sulfate Mimetic Fucoidan Restores the Endothelial Glycocalyx and Protects Against Dysfunction Induced by Serum of COVID-19 Patients in the Intensive Care Unit ERJ Open Research. Apr, 2022 | Pubmed ID: 35509442 Compassionate Use of Avacopan in Difficult-to-Treat Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Kidney International Reports. Mar, 2022 | Pubmed ID: 35257076 Will New Treatment Options for Lupus Nephritis Be Affordable? Clinical Journal of the American Society of Nephrology : CJASN. Mar, 2022 | Pubmed ID: 35121594 Mutations in the Heparan Sulfate Backbone Elongating Enzymes EXT1 and EXT2 Have No Major Effect on Endothelial Glycocalyx and the Glomerular Filtration Barrier Molecular Genetics and Genomics : MGG. Mar, 2022 | Pubmed ID: 35103870 Circulating MiRNAs and Vascular Injury Markers Associate with Cardiovascular Function in Older Patients Reaching End-Stage Kidney Disease Non-coding RNA. Jan, 2022 | Pubmed ID: 35076541 Circulating Angiopoietin-2 and Angiogenic MicroRNAs Associate with Cerebral Small Vessel Disease and Cognitive Decline in Older Patients Reaching End-stage Renal Disease Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Feb, 2022 | Pubmed ID: 33355649 Single-Cell Transcriptomics Links Loss of Human Pancreatic β-Cell Identity to ER Stress Cells. Dec, 2021 | Pubmed ID: 34944092 Blocking of Inflammatory Heparan Sulfate Domains by Specific Antibodies is Not Protective in Experimental Glomerulonephritis PloS One. 2021 | Pubmed ID: 34941931 Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity Frontiers in Immunology. 2021 | Pubmed ID: 34804002 The Association of Glucose Metabolism and Kidney Function in Middle-aged Adults Clinical Kidney Journal. Nov, 2021 | Pubmed ID: 34754434 Clinical Practice Audit on the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis in the Netherlands Kidney International Reports. Oct, 2021 | Pubmed ID: 34622106 Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies Frontiers in Immunology. 2021 | Pubmed ID: 34489931 Thresholds of Endoglin Expression in Endothelial Cells Explains Vascular Etiology in Hereditary Hemorrhagic Telangiectasia Type 1 International Journal of Molecular Sciences. Aug, 2021 | Pubmed ID: 34445652 Estradiol-driven Metabolism in Transwomen Associates with Reduced Circulating Extracellular Vesicle MicroRNA-224/452 European Journal of Endocrinology. Aug, 2021 | Pubmed ID: 34342596 Microvascular Differences in Individuals with Obesity at Risk of Developing Cardiovascular Disease Obesity (Silver Spring, Md.). Sep, 2021 | Pubmed ID: 34338418 Thiol-ene Cross-linked Alginate Hydrogel Encapsulation Modulates the Extracellular Matrix of Kidney Organoids by Reducing Abnormal Type 1a1 Collagen Deposition Biomaterials. Aug, 2021 | Pubmed ID: 34198162 Imaging the Renal Microcirculation in Cell Therapy Cells. May, 2021 | Pubmed ID: 34063200 Effectiveness of a Multidisciplinary Clinical Pathway for Women with Systemic Lupus Erythematosus And/or Antiphospholipid Syndrome Lupus Science & Medicine. May, 2021 | Pubmed ID: 33952625 Home Monitoring Reduced Short Stay Admissions in Suspected COVID-19 Patients: COVID-box Project The European Respiratory Journal. Aug, 2021 | Pubmed ID: 33795321 Phenotypic Diversity and Metabolic Specialization of Renal Endothelial Cells Nature Reviews. Nephrology. Jul, 2021 | Pubmed ID: 33767431 Netrin-4 Expression by Human Endothelial Cells Inhibits Endothelial Inflammation and Senescence The International Journal of Biochemistry & Cell Biology. May, 2021 | Pubmed ID: 33636396 The Impact of Transvenous Cardioverter-defibrillator Implantation on Quality of Life, Depression and Optimism in Dialysis Patients: Report on the Secondary Outcome of QOL in the Randomized Controlled ICD2 Trial Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. Jun, 2021 | Pubmed ID: 33606179 Autologous Bone Marrow-derived Mesenchymal Stromal Cell Therapy with Early Tacrolimus Withdrawal: The Randomized Prospective, Single-center, Open-label TRITON Study American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Sep, 2021 | Pubmed ID: 33565206 Dichotomic Role of Heparanase in a Murine Model of Metabolic Syndrome Cellular and Molecular Life Sciences : CMLS. Mar, 2021 | Pubmed ID: 33051777 PR3-ANCAs Predict Relapses in ANCA-associated Vasculitis Patients After Rituximab Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Jul, 2021 | Pubmed ID: 32601673 Long-term Effects of Combined B-cell Immunomodulation with Rituximab and Belimumab in Severe, Refractory Systemic Lupus Erythematosus: 2-year Results Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Jul, 2021 | Pubmed ID: 32591783 Targeting the RNA-Binding Protein in Myeloid Cells Ameliorates Macrophage-Induced Renal Interstitial Fibrosis Epigenomes. Feb, 2020 | Pubmed ID: 34968236 Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients Frontiers in Immunology. 2020 | Pubmed ID: 33384685 MicroRNA-132 Regulates Salt-dependent Steady-state Renin Levels in Mice Communications Biology. May, 2020 | Pubmed ID: 32409785 Assessment of Size-Selective Glomerular Sieving in Transplanted Human Induced Pluripotent Stem Cell-Derived Kidney Organoids Journal of the American Society of Nephrology : JASN. May, 2020 | Pubmed ID: 32354986 Patterns and Characteristics of Cognitive Functioning in Older Patients Approaching End Stage Kidney Disease, the COPE-study BMC Nephrology. Apr, 2020 | Pubmed ID: 32272897 Loss of Endothelial Glycocalyx Hyaluronan Impairs Endothelial Stability and Adaptive Vascular Remodeling After Arterial Ischemia Cells. Mar, 2020 | Pubmed ID: 32235347 Lowering the Increased Intracellular PH of Human-induced Pluripotent Stem Cell-derived Endothelial Cells Induces Formation of Mature Weibel-Palade Bodies Stem Cells Translational Medicine. Jul, 2020 | Pubmed ID: 32163224 Effect of No Prehydration Vs Sodium Bicarbonate Prehydration Prior to Contrast-Enhanced Computed Tomography in the Prevention of Postcontrast Acute Kidney Injury in Adults With Chronic Kidney Disease: The Kompas Randomized Clinical Trial JAMA Internal Medicine. Apr, 2020 | Pubmed ID: 32065601 Endothelial Glycocalyx Hyaluronan: Regulation and Role in Prevention of Diabetic Complications The American Journal of Pathology. Apr, 2020 | Pubmed ID: 32035886 Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2020 | Pubmed ID: 31826652 Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation Journal of the American Society of Nephrology : JASN. Jan, 2020 | Pubmed ID: 31818909 Stem Cell-derived Kidney Organoids: Engineering the Vasculature Cellular and Molecular Life Sciences : CMLS. Jun, 2020 | Pubmed ID: 31807815 Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure Diabetes. 02, 2020 | Pubmed ID: 31732500 The Separate Contributions of Visceral Fat and Liver Fat to Chronic Kidney Disease-Related Renal Outcomes Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation. Jul, 2020 | Pubmed ID: 31668939 Closing the Mitochondrial Permeability Transition Pore in HiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation Stem Cell Reports. Oct, 2019 | Pubmed ID: 31680061 Highly Efficient Ex Vivo Lentiviral Transduction of Primary Human Pancreatic Exocrine Cells Scientific Reports. Nov, 2019 | Pubmed ID: 31676849 The Neglectable Impact of Delayed Graft Function on Long-term Graft Survival in Kidneys Donated After Circulatory Death Associates With Superior Organ Resilience Annals of Surgery. Nov, 2019 | Pubmed ID: 31567503 Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic MiRNAs Between Extracellular Vesicles, HDL and Ago-2 Diabetes. Sep, 2019 | Pubmed ID: 31506344 New Insights into Energy and Protein Homeostasis by the Kidney Nature Reviews. Nephrology. Oct, 2019 | Pubmed ID: 31388129 Low Birth Weight and Kidney Function in Middle-Aged Men and Women: The Netherlands Epidemiology of Obesity Study American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. Dec, 2019 | Pubmed ID: 31358312 Intrinsically Distinct Role of Neutrophil Extracellular Trap Formation in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Compared to Systemic Lupus Erythematosus Arthritis & Rheumatology (Hoboken, N.J.). Dec, 2019 | Pubmed ID: 31313503 Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium Journal of the American Society of Nephrology : JASN. Oct, 2019 | Pubmed ID: 31308073 A Catalog of Genetic Loci Associated with Kidney Function from Analyses of a Million Individuals Nature Genetics. Jun, 2019 | Pubmed ID: 31152163 Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis Frontiers in Pharmacology. 2019 | Pubmed ID: 30914951 Prophylactic Use of Implantable Cardioverter-Defibrillators in the Prevention of Sudden Cardiac Death in Dialysis Patients Circulation. Jun, 2019 | Pubmed ID: 30882234 Clinical Implications of Excessive Neutrophil Extracellular Trap Formation in Renal Autoimmune Diseases Kidney International Reports. Feb, 2019 | Pubmed ID: 30775617 Neutral Endopeptidase Inhibitors Blunt Kidney Fibrosis by Reducing Myofibroblast Formation Clinical Science (London, England : 1979). 01, 2019 | Pubmed ID: 30617188 Concise Review: The Endothelial Cell Extracellular Matrix Regulates Tissue Homeostasis and Repair Stem Cells Translational Medicine. Apr, 2019 | Pubmed ID: 30537441 Vascular Bioengineering of Scaffolds Derived from Human Discarded Transplant Kidneys Using Human Pluripotent Stem Cell-derived Endothelium American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 05, 2019 | Pubmed ID: 30506641 Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2 Circulation. 12, 2018 | Pubmed ID: 30571259 Chronic Kidney Failure Mineral Bone Disorder Leads to a Permanent Loss of Hematopoietic Stem Cells Through Dysfunction of the Stem Cell Niche Scientific Reports. 10, 2018 | Pubmed ID: 30337617 MicroRNA-132 Controls Water Homeostasis Through Regulating MECP2-mediated Vasopressin Synthesis American Journal of Physiology. Renal Physiology. 10, 2018 | Pubmed ID: 29846108 The NET-effect of Combining Rituximab with Belimumab in Severe Systemic Lupus Erythematosus Journal of Autoimmunity. Jul, 2018 | Pubmed ID: 29636274 Excessive Neutrophil Extracellular Trap Formation in ANCA-associated Vasculitis is Independent of ANCA Kidney International. 07, 2018 | Pubmed ID: 29606398 Associations Between Normal Range Albuminuria, Renal Function and Cardiovascular Function in a Population-based Imaging Study Atherosclerosis. May, 2018 | Pubmed ID: 29579673 Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential Stem Cell Reports. Mar, 2018 | Pubmed ID: 29539434 Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo Stem Cell Reports. Mar, 2018 | Pubmed ID: 29503086 Randomized Trial of One-hour Sodium Bicarbonate Vs Standard Periprocedural Saline Hydration in Chronic Kidney Disease Patients Undergoing Cardiovascular Contrast Procedures PloS One. 2018 | Pubmed ID: 29420536 Renal Metabolism in 2017: Glycolytic Adaptation and Progression of Kidney Disease Nature Reviews. Nephrology. Feb, 2018 | Pubmed ID: 29292369 An Evidence-based Approach to Pre-pregnancy Counselling for Patients with Systemic Lupus Erythematosus Rheumatology (Oxford, England). Oct, 2018 | Pubmed ID: 29165607 Metabolic Imaging of Fatty Kidney in Diabesity: Validation and Dietary Intervention Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 02, 2018 | Pubmed ID: 28992141 Self-Monitoring Kidney Function Post Transplantation: Reliability of Patient-Reported Data Journal of Medical Internet Research. Sep, 2017 | Pubmed ID: 28951385 Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy The American Journal of Pathology. Nov, 2017 | Pubmed ID: 28837800 Lupus Nephritis: Mesenchymal Stromal Cells in Lupus Nephritis Nature Reviews. Nephrology. Jul, 2017 | Pubmed ID: 28719600 Acute Rejection After Kidney Transplantation Associates With Circulating MicroRNAs and Vascular Injury Transplantation Direct. Jul, 2017 | Pubmed ID: 28706977 Mesenchymal Stromal Cell Therapy for Solid Organ Transplantation Transplantation. Jul, 2017 | Pubmed ID: 28704335 The Cognitive Decline in Older Patients with End Stage Renal Disease (COPE) Study - Rationale and Design Current Medical Research and Opinion. Jul, 2017 | Pubmed ID: 28604116 Renal Physiology: Burning Calories to Excrete Salt Nature Reviews. Nephrology. Jun, 2017 | Pubmed ID: 28480904 Clinical-Grade Isolated Human Kidney Perivascular Stromal Cells As an Organotypic Cell Source for Kidney Regenerative Medicine Stem Cells Translational Medicine. Feb, 2017 | Pubmed ID: 28191776 Heparanase: Roles in Cell Survival, Extracellular Matrix Remodelling and the Development of Kidney Disease Nature Reviews. Nephrology. Apr, 2017 | Pubmed ID: 28163306 Direct Observation of Enhanced Nitric Oxide in a Murine Model of Diabetic Nephropathy PloS One. 2017 | Pubmed ID: 28103268 Emerging Roles for RNA-binding Proteins As Effectors and Regulators of Cardiovascular Disease European Heart Journal. May, 2017 | Pubmed ID: 28064149 MiRNA-Coordinated Networks As Promising Therapeutic Targets for Acute Kidney Injury The American Journal of Pathology. Jan, 2017 | Pubmed ID: 27865759 TAC-TIC Use of Tacrolimus-based Regimens in Lupus Nephritis Lupus Science & Medicine. 2016 | Pubmed ID: 28123768 RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues PloS One. 2016 | Pubmed ID: 27898729 Mesenchymal Stromal Cells in Clinical Kidney Transplantation: How Tolerant Can It Be? Current Opinion in Organ Transplantation. Dec, 2016 | Pubmed ID: 27755168 Echocardiographic Associates of Atrial Fibrillation in End-stage Renal Disease Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Sep, 2016 | Pubmed ID: 27688260 Promoting Tropoelastin Expression in Arterial and Venous Vascular Smooth Muscle Cells and Fibroblasts for Vascular Tissue Engineering Tissue Engineering. Part C, Methods. Oct, 2016 | Pubmed ID: 27604583 Cathepsin L is Crucial for the Development of Early Experimental Diabetic Nephropathy Kidney International. Nov, 2016 | Pubmed ID: 27575559 Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria PloS One. 2016 | Pubmed ID: 27505185 Liposomal Prednisolone Inhibits Vascular Inflammation and Enhances Venous Outward Remodeling in a Murine Arteriovenous Fistula Model Scientific Reports. 2016 | Pubmed ID: 27460883 Macrophages in Diabetic Nephropathy in Patients with Type 2 Diabetes Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Jul, 2016 | Pubmed ID: 27416772 Modelling the Cost-Effectiveness of Delaying End-Stage Renal Disease Nephron. 2016 | Pubmed ID: 27270045 Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy Diabetes. Aug, 2016 | Pubmed ID: 27207530 Silencing of MicroRNA-132 Reduces Renal Fibrosis by Selectively Inhibiting Myofibroblast Proliferation Kidney International. Jun, 2016 | Pubmed ID: 27165825 Is the Prevalence of Hypertension in Overweight Children Overestimated? Archives of Disease in Childhood. Nov, 2016 | Pubmed ID: 27045117 Quaking Promotes Monocyte Differentiation into Pro-atherogenic Macrophages by Controlling Pre-mRNA Splicing and Gene Expression Nature Communications. Mar, 2016 | Pubmed ID: 27029405 Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx Journal of the American Society of Nephrology : JASN. Dec, 2016 | Pubmed ID: 27026367 Azathioprine-induced Eosinophilic Myocarditis in a Patient with ANCA-associated Vasculitis Clinical and Experimental Rheumatology. May-Jun, 2016 | Pubmed ID: 26950304 A Novel Method for High-throughput Detection and Quantification of Neutrophil Extracellular Traps Reveals ROS-independent NET Release with Immune Complexes Autoimmunity Reviews. Jun, 2016 | Pubmed ID: 26925759 The RNA-binding Protein Quaking Maintains Endothelial Barrier Function and Affects VE-cadherin and β-catenin Protein Expression Scientific Reports. Feb, 2016 | Pubmed ID: 26905650 Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis The American Journal of Pathology. Apr, 2016 | Pubmed ID: 26873445 Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro The Journal of Biological Chemistry. Mar, 2016 | Pubmed ID: 26728463 Candidate Gene Analysis of Mortality in Dialysis Patients PloS One. 2015 | Pubmed ID: 26587841 Safety of Allogeneic Bone Marrow Derived Mesenchymal Stromal Cell Therapy in Renal Transplant Recipients: the Neptune Study Journal of Translational Medicine. Nov, 2015 | Pubmed ID: 26537851 Serum Cardiac Troponin-I is Superior to Troponin-T As a Marker for Left Ventricular Dysfunction in Clinically Stable Patients with End-Stage Renal Disease PloS One. 2015 | Pubmed ID: 26237313 Vitamin D Attenuates Proteinuria by Inhibition of Heparanase Expression in the Podocyte The Journal of Pathology. Dec, 2015 | Pubmed ID: 26202309 Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits Diabetes. Aug, 2015 | Pubmed ID: 25918235 Early Systemic Microvascular Damage in Pigs with Atherogenic Diabetes Mellitus Coincides with Renal Angiopoietin Dysbalance PloS One. 2015 | Pubmed ID: 25909188 No Increase in Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin Excretion Following Intravenous Contrast Enhanced-CT European Radiology. Jul, 2015 | Pubmed ID: 25773936 A Microscopic View on the Renal Endothelial Glycocalyx American Journal of Physiology. Renal Physiology. May, 2015 | Pubmed ID: 25673809 Guideline Treatment Results in Regression of Atherosclerosis in Type 2 Diabetes Mellitus Diabetes & Vascular Disease Research. Mar, 2015 | Pubmed ID: 25589481 Tailoring the Foreign Body Response for in Situ Vascular Tissue Engineering Tissue Engineering. Part C, Methods. May, 2015 | Pubmed ID: 25336286 The Role of Heparan Sulfate As Determining Pathogenic Factor in Complement Factor H-associated Diseases Molecular Immunology. Feb, 2015 | Pubmed ID: 25246018 The Role of MicroRNA-126 in Vascular Homeostasis Current Vascular Pharmacology. 2015 | Pubmed ID: 23713864 Silencing of MiRNA-126 in Kidney Ischemia Reperfusion is Associated with Elevated SDF-1 Levels and Mobilization of Sca-1+/Lin- Progenitor Cells MicroRNA (Shariqah, United Arab Emirates). 2014 | Pubmed ID: 25541911 Soluble Klotho is Not Independently Associated with Cardiovascular Disease in a Population of Dialysis Patients BMC Nephrology. Dec, 2014 | Pubmed ID: 25495997 Autologous Bone Marrow Derived Mesenchymal Stromal Cell Therapy in Combination with Everolimus to Preserve Renal Structure and Function in Renal Transplant Recipients Journal of Translational Medicine. Dec, 2014 | Pubmed ID: 25491391 Differential Complement Activation Pathways Promote C3b Deposition on Native and Acetylated LDL Thereby Inducing Lipoprotein Binding to the Complement Receptor 1 The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25349208 Erythropoiesis-stimulating Agents and Thrombotic Events in Dialysis Patients Thrombosis Research. Nov, 2014 | Pubmed ID: 25242244 A Case for Crowd Sourcing in Stem Cell Research Stem Cells Translational Medicine. Nov, 2014 | Pubmed ID: 25232185 Clinical Translation of Multipotent Mesenchymal Stromal Cells in Transplantation Seminars in Nephrology. Jul, 2014 | Pubmed ID: 25217264 Belimumab After Rituximab As Maintenance Therapy in Lupus Nephritis Rheumatology (Oxford, England). Nov, 2014 | Pubmed ID: 25205827 Islet-after-lung Transplantation in a Patient with Cystic Fibrosis-related Diabetes Diabetes Care. Jul, 2014 | Pubmed ID: 24963115 Telomere Shortening: a Diagnostic Tool and Therapeutic Target for Cardiovascular Disease? European Heart Journal. Dec, 2014 | Pubmed ID: 24957071 Efficacy and Safety of Vitamin K-antagonists (VKA) for Atrial Fibrillation in Non-dialysis Dependent Chronic Kidney Disease PloS One. 2014 | Pubmed ID: 24817475 Associations of Atherosclerosis in the Descending Thoracic Aorta on CTA with Arterial Stiffness and Chronic Kidney Disease in Asymptomatic Patients with Diabetes Mellitus The International Journal of Cardiovascular Imaging. Aug, 2014 | Pubmed ID: 24816844 Deeper Penetration of Erythrocytes into the Endothelial Glycocalyx is Associated with Impaired Microvascular Perfusion PloS One. 2014 | Pubmed ID: 24816787 Chronic Kidney Disease and Implantable Cardioverter Defibrillator Related Complications: 16 Years of Experience Journal of Cardiovascular Electrophysiology. Sep, 2014 | Pubmed ID: 24758287 Hematopoietic MicroRNA-126 Protects Against Renal Ischemia/reperfusion Injury by Promoting Vascular Integrity Journal of the American Society of Nephrology : JASN. Aug, 2014 | Pubmed ID: 24610930 A Randomized Comparison of 1-h Sodium Bicarbonate Hydration Versus Standard Peri-procedural Saline Hydration in Patients with Chronic Kidney Disease Undergoing Intravenous Contrast-enhanced Computerized Tomography Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. May, 2014 | Pubmed ID: 24578471 Association of Kidney Function with Changes in the Endothelial Surface Layer Clinical Journal of the American Society of Nephrology : CJASN. Apr, 2014 | Pubmed ID: 24458084 Long-term Ketogenic Diet Causes Glucose Intolerance and Reduced β- and α-cell Mass but No Weight Loss in Mice American Journal of Physiology. Endocrinology and Metabolism. Mar, 2014 | Pubmed ID: 24398402 Mesenchymal Stromal Cells to Prevent Fibrosis in Kidney Transplantation Current Opinion in Organ Transplantation. Feb, 2014 | Pubmed ID: 24275894 Mesenchymal Stromal Cell Therapy for Cardio Renal Disorders Current Pharmaceutical Design. 2014 | Pubmed ID: 23844816 Vascular Remodeling and Intimal Hyperplasia in a Novel Murine Model of Arteriovenous Fistula Failure Journal of Vascular Surgery. Jan, 2014 | Pubmed ID: 23684425 Human Bone Marrow- and Adipose Tissue-derived Mesenchymal Stromal Cells Are Immunosuppressive In Vitro and in a Humanized Allograft Rejection Model Journal of Stem Cell Research & Therapy. Nov, 2013 | Pubmed ID: 24672744 Performance of Cockcroft-Gault, MDRD, and CKD-EPI in Estimating Prevalence of Renal Function and Predicting Survival in the Oldest Old BMC Geriatrics. Oct, 2013 | Pubmed ID: 24160772 Echocardiographical Determinants of an Abnormal Spatial QRS-T Angle in Chronic Dialysis Patients Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Dec, 2013 | Pubmed ID: 24092849 Maximising Impact of Small Cohort Studies Transplant International : Official Journal of the European Society for Organ Transplantation. Sep, 2013 | Pubmed ID: 23947717 Abdominal Adiposity Largely Explains Associations Between Insulin Resistance, Hyperglycemia and Subclinical Atherosclerosis: the NEO Study Atherosclerosis. Aug, 2013 | Pubmed ID: 23880198 CT Coronary Angiography is Feasible for the Assessment of Coronary Artery Disease in Chronic Dialysis Patients, Despite High Average Calcium Scores PloS One. 2013 | Pubmed ID: 23874471 Renal Ischemia-reperfusion Induces Release of Angiopoietin-2 from Human Grafts of Living and Deceased Donors Transplantation. Aug, 2013 | Pubmed ID: 23839000 Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: Lessons Learned from First Clinical Trials Transplantation. Aug, 2013 | Pubmed ID: 23759879 Metabolic Imaging of Human Kidney Triglyceride Content: Reproducibility of Proton Magnetic Resonance Spectroscopy PloS One. 2013 | Pubmed ID: 23620813 Conversion of Mature Human β-cells into Glucagon-producing α-cells Diabetes. Jul, 2013 | Pubmed ID: 23569174 Candidate Gene Analysis of Arteriovenous Fistula Failure in Hemodialysis Patients Clinical Journal of the American Society of Nephrology : CJASN. Aug, 2013 | Pubmed ID: 23559680 Arteriovenous Access Failure: More Than Just Intimal Hyperplasia? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. May, 2013 | Pubmed ID: 23543595 Glomerular Endothelial Surface Layer Acts As a Barrier Against Albumin Filtration The American Journal of Pathology. May, 2013 | Pubmed ID: 23518410 Topologically Heterogeneous Beta Cell Adaptation in Response to High-fat Diet in Mice PloS One. 2013 | Pubmed ID: 23441226 Bone Marrow-derived Mesenchymal Stromal Cells from Patients with End-stage Renal Disease Are Suitable for Autologous Therapy Cytotherapy. Jun, 2013 | Pubmed ID: 23419679 Aspirin Treatment Hampers the Use of Plasma MicroRNA-126 As a Biomarker for the Progression of Vascular Disease European Heart Journal. Nov, 2013 | Pubmed ID: 23386708 The Endothelial Glycocalyx As a Potential Modifier of the Hemolytic Uremic Syndrome European Journal of Internal Medicine. Sep, 2013 | Pubmed ID: 23357408 Autologous Bone Marrow-derived Mesenchymal Stromal Cells for the Treatment of Allograft Rejection After Renal Transplantation: Results of a Phase I Study Stem Cells Translational Medicine. Feb, 2013 | Pubmed ID: 23349326 A Possible Role of Cystatin C in Adipose Tissue Homeostasis May Impact Kidney Function Estimation in Metabolic Syndrome Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Jul, 2013 | Pubmed ID: 23262435 The Role of Mesenchymal Stromal Cells in Chronic Transplant Rejection After Solid Organ Transplantation Current Opinion in Organ Transplantation. Feb, 2013 | Pubmed ID: 23254697 Relationship Between Left Ventricular Diastolic Function and Arterial Stiffness in Asymptomatic Patients with Diabetes Mellitus The International Journal of Cardiovascular Imaging. Mar, 2013 | Pubmed ID: 23053856 Incremental Prognostic Value of an Abnormal Baseline Spatial QRS-T Angle in Chronic Dialysis Patients Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Feb, 2013 | Pubmed ID: 23024335 MicroRNA-155 Functions As a Negative Regulator of RhoA Signaling in TGF-β-induced Endothelial to Mesenchymal Transition MicroRNA (Shariqah, United Arab Emirates). 2012 | Pubmed ID: 25048084 Late Calcineurin Inhibitor Withdrawal Prevents Progressive Left Ventricular Diastolic Dysfunction in Renal Transplant Recipients Transplantation. Oct, 2012 | Pubmed ID: 22955227 Republished: How to Reduce Sudden Cardiac Death in Patients with Renal Failure Postgraduate Medical Journal. Jul, 2012 | Pubmed ID: 22730485 Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis: Prevalence and Determinants International Journal of Nephrology. 2012 | Pubmed ID: 22649726 How to Reduce Sudden Cardiac Death in Patients with Renal Failure Heart (British Cardiac Society). Feb, 2012 | Pubmed ID: 22267816 Dexamethasone Increases ROS Production and T Cell Suppressive Capacity by Anti-inflammatory Macrophages Molecular Immunology. Dec, 2011 | Pubmed ID: 22047959 Immunosuppression and the Abdominal Aortic Aneurysm: Doctor Jekyll or Mister Hyde? Circulation. Nov, 2011 | Pubmed ID: 22042930 Relationship Between Vascular Stiffness and Stress Myocardial Perfusion Imaging in Asymptomatic Patients with Diabetes European Journal of Nuclear Medicine and Molecular Imaging. Nov, 2011 | Pubmed ID: 21850500 Low Mannose-Binding Lectin (MBL) Genotype is Associated with Future Cardiovascular Events in Type 2 Diabetic South Asians. A Prospective Cohort Study Cardiovascular Diabetology. Jul, 2011 | Pubmed ID: 21729275 How to Reduce the Incidence of Contrast Induced Acute Kidney Injury After Cardiac Invasive Procedures, a Review and Practical Recommendations Current Medical Research and Opinion. Jul, 2011 | Pubmed ID: 21561396 [Endothelial Progenitor Cells: What Are We Talking About?] Nephrologie & Therapeutique. Dec, 2011 | Pubmed ID: 21334277 Improved Viscosity Modeling in Patients with Type 2 Diabetes Mellitus by Accounting for Enhanced Red Blood Cell Aggregation Tendency Clinical Hemorheology and Microcirculation. 2010 | Pubmed ID: 20571245 Endothelial Activation and Circulating Markers of Endothelial Activation in Kidney Disease Nature Reviews. Nephrology. Jul, 2010 | Pubmed ID: 20498676 Urinary Properdin Excretion is Associated with Intrarenal Complement Activation and Poor Renal Function Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Apr, 2010 | Pubmed ID: 19934084 Increased Carotid Intima-media Thickness As a Predictor of the Presence and Extent of Abnormal Myocardial Perfusion in Type 2 Diabetes Diabetes Care. Feb, 2010 | Pubmed ID: 19918012 Endothelial Dysfunction in Diabetic Patients with Abnormal Myocardial Perfusion in the Absence of Epicardial Obstructive Coronary Artery Disease Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Dec, 2009 | Pubmed ID: 19910438 Usefulness of Carotid Intima-media Thickness in Patients with Diabetes Mellitus As a Predictor of Coronary Artery Disease The American Journal of Cardiology. Oct, 2009 | Pubmed ID: 19801021 Salt is Getting Under Our Skin Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Nov, 2009 | Pubmed ID: 19675060 The Current Status of Interventions Aiming at Reducing Sudden Cardiac Death in Dialysis Patients European Heart Journal. Jul, 2009 | Pubmed ID: 19465437 Differentiation of Bone Marrow-derived Endothelial Progenitor Cells is Shifted into a Proinflammatory Phenotype by Hyperglycemia Molecular Medicine (Cambridge, Mass.). May-Jun, 2009 | Pubmed ID: 19295918 Antagomir-mediated Silencing of Endothelial Cell Specific MicroRNA-126 Impairs Ischemia-induced Angiogenesis Journal of Cellular and Molecular Medicine. Aug, 2009 | Pubmed ID: 19120690 Optimal Predialysis Care NDT Plus. Oct, 2008 | Pubmed ID: 25983991 Complement Activation by Tubular Cells is Mediated by Properdin Binding American Journal of Physiology. Renal Physiology. Nov, 2008 | Pubmed ID: 18753294 Prevention of Sudden Cardiac Death: Rationale and Design of the Implantable Cardioverter Defibrillators in Dialysis Patients (ICD2) Trial--a Prospective Pilot Study Current Medical Research and Opinion. Aug, 2008 | Pubmed ID: 18561878 Hypertension and Rarefaction During Treatment with Telatinib, a Small Molecule Angiogenesis Inhibitor Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2008 | Pubmed ID: 18519779 Recombinant Human GH Replacement Increases CD34+ Cells and Improves Endothelial Function in Adults with GH Deficiency European Journal of Endocrinology. Aug, 2008 | Pubmed ID: 18495694 Preservation of Beta-cell Function by Targeting Beta-cell Mass Trends in Pharmacological Sciences. Apr, 2008 | Pubmed ID: 18359095 Opportunities and Challenges for Mesenchymal Stem Cell-mediated Heart Repair Current Opinion in Lipidology. Dec, 2007 | Pubmed ID: 17993810 New Horizons in Prevention and Treatment of Ischaemic Injury to Kidney Transplants Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Feb, 2007 | Pubmed ID: 17132706 Endothelial Progenitor Cells: Biology and Therapeutic Potential in Hypertension Current Opinion in Nephrology and Hypertension. Mar, 2006 | Pubmed ID: 16481884 Endothelial Nitric Oxide Synthase: Host Defense Enzyme of the Endothelium? Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2006 | Pubmed ID: 16293798 Endothelial Progenitor Cell Dysfunction in Type 1 Diabetes: Another Consequence of Oxidative Stress? Antioxidants & Redox Signaling. Nov-Dec, 2005 | Pubmed ID: 16356109 The Role of Nitric Oxide in Renal Transplantation Seminars in Nephrology. Jul, 2004 | Pubmed ID: 15252777 Pharmacogenetics of the CD14 Endotoxin Receptor Polymorphism and Progression of Coronary Atherosclerosis Thrombosis and Haemostasis. May, 2004 | Pubmed ID: 15116260 An Integrated Evaluation of Endothelial Constitutive Nitric Oxide Synthase Polymorphisms and Coronary Artery Disease in Men Clinical Science (London, England : 1979). Sep, 2004 | Pubmed ID: 15068395 Endothelial Progenitor Cells: More Than an Inflammatory Response? Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2004 | Pubmed ID: 15001453 Vascularização Eficiente de Organoides Renais através do Transplante Intracelomico em Embriões de Galinha Marije Koning1,2, Ellen Lievers1,2, Thierry Jaffredo3, Cathelijne W. van den Berg1,2,4, Ton J. Rabelink1,2,4 1Department of Internal Medicine - Nephrology, Leiden University Medical Center, 2Einthoven Laboratory of Vascular and Regenerative Medicine, Leiden University Medical Center, 3IBPS, CNRS UMR7622, Developmental Biology Laboratory, Sorbonne Université, 4The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center JoVE 65090 Developmental Biology Um ensaio de alta produtividade para avaliar e quantificar a formação de neutrófilos extracelular armadilha Eline J. Arends*1, Laura S. van Dam*1, Tineke Kraaij1, Sylvia W.A. Kamerling1, Ton J. Rabelink1, Cees van Kooten1, Y.K. Onno Teng1 1Department of Nephrology, Leiden University Medical Center JoVE 59150 Immunology and Infection Um método de isolamento do romance grau clínico para rim humano Perivascular de células do estroma Daniëlle G. Leuning1, Ellen Lievers1, Marlies E.J. Reinders1, Cees van Kooten1, Marten A. Engelse1, Ton J. Rabelink1 1Department of Internal Medicine, Leiden University Medical Centre JoVE 55841 Medicine Um Modelo murino Novel de Fístula Arteriovenosa Falha: O procedimento cirúrgico em Detalhe Chun Yu Wong1,2,3, Margreet R. de Vries2,3, Yang Wang4, Joost R. van der Vorst3, Alexander L. Vahrmeijer3, Anton-Jan van Zonneveld1,2, Jaap F. Hamming3, Prabir Roy-Chaudhury4, Ton J. Rabelink1,2, Paul H. A. Quax2,3, Joris I. Rotmans1,2 1Department of Nephrology, Leiden University Medical Center, 2Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 3Department of Surgery, Leiden University Medical Center, 4Division of Nephrology, University of Cincinnati Medicine
Vascularização Eficiente de Organoides Renais através do Transplante Intracelomico em Embriões de Galinha Marije Koning1,2, Ellen Lievers1,2, Thierry Jaffredo3, Cathelijne W. van den Berg1,2,4, Ton J. Rabelink1,2,4 1Department of Internal Medicine - Nephrology, Leiden University Medical Center, 2Einthoven Laboratory of Vascular and Regenerative Medicine, Leiden University Medical Center, 3IBPS, CNRS UMR7622, Developmental Biology Laboratory, Sorbonne Université, 4The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center JoVE 65090 Developmental Biology
Um ensaio de alta produtividade para avaliar e quantificar a formação de neutrófilos extracelular armadilha Eline J. Arends*1, Laura S. van Dam*1, Tineke Kraaij1, Sylvia W.A. Kamerling1, Ton J. Rabelink1, Cees van Kooten1, Y.K. Onno Teng1 1Department of Nephrology, Leiden University Medical Center JoVE 59150 Immunology and Infection
Um método de isolamento do romance grau clínico para rim humano Perivascular de células do estroma Daniëlle G. Leuning1, Ellen Lievers1, Marlies E.J. Reinders1, Cees van Kooten1, Marten A. Engelse1, Ton J. Rabelink1 1Department of Internal Medicine, Leiden University Medical Centre JoVE 55841 Medicine
Um Modelo murino Novel de Fístula Arteriovenosa Falha: O procedimento cirúrgico em Detalhe Chun Yu Wong1,2,3, Margreet R. de Vries2,3, Yang Wang4, Joost R. van der Vorst3, Alexander L. Vahrmeijer3, Anton-Jan van Zonneveld1,2, Jaap F. Hamming3, Prabir Roy-Chaudhury4, Ton J. Rabelink1,2, Paul H. A. Quax2,3, Joris I. Rotmans1,2 1Department of Nephrology, Leiden University Medical Center, 2Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 3Department of Surgery, Leiden University Medical Center, 4Division of Nephrology, University of Cincinnati Medicine
