Vann Bennett

Publications

• Neurodevelopmental Mutation of Giant Ankyrin-G Disrupts a Core Mechanism for Axon Initial Segment Assembly
  Proceedings of the National Academy of Sciences of the United States of America. 09, 2019  |   Pubmed ID: 31451636
• Autism Mutation Targeting Giant Ankyrin-B Promotes Axon Branching and Ectopic Connectivity
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2019  |   Pubmed ID: 31285321
• βII-spectrin Promotes Mouse Brain Connectivity Through Stabilizing Axonal Plasma Membranes and Enabling Axonal Organelle Transport
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2019  |   Pubmed ID: 31209033
• Ankyrin-G Regulated Epithelial Phenotype is Required for Mouse Lens Morphogenesis and Growth
  Developmental Biology. 02, 2019  |   Pubmed ID: 30562487
• Cell-autonomous Adiposity Through Increased Cell Surface GLUT4 Due to Ankyrin-B Deficiency
  Proceedings of the National Academy of Sciences of the United States of America. 11, 2017  |   Pubmed ID: 29133412
• Ankyrin-B is a PI3P Effector That Promotes Polarized α5β1-integrin Recycling Via Recruiting RabGAP1L to Early Endosomes
  ELife. 10, 2016  |   Pubmed ID: 27718357
• An Adaptable Spectrin/Ankyrin-Based Mechanism for Long-Range Organization of Plasma Membranes in Vertebrate Tissues
  Current Topics in Membranes. 2016  |   Pubmed ID: 26781832
• Ankyrin-G Inhibits Endocytosis of Cadherin Dimers
  The Journal of Biological Chemistry. Jan, 2016  |   Pubmed ID: 26574545
• Ankyrin-B Directs Membrane Tethering of Periaxin and is Required for Maintenance of Lens Fiber Cell Hexagonal Shape and Mechanics
  American Journal of Physiology. Cell Physiology. Jan, 2016  |   Pubmed ID: 26538089
• Dynamic Spectrin/ankyrin-G Microdomains Promote Lateral Membrane Assembly by Opposing Endocytosis
  Science Advances. Sep, 2015  |   Pubmed ID: 26523289
• Ankyrin-B Metabolic Syndrome Combines Age-dependent Adiposity with Pancreatic β Cell Insufficiency
  The Journal of Clinical Investigation. Aug, 2015  |   Pubmed ID: 26168218
• Evolution in Action: Giant Ankyrins Awake
  Developmental Cell. Apr, 2015  |   Pubmed ID: 25850669
• Giant Ankyrin-G Stabilizes Somatodendritic GABAergic Synapses Through Opposing Endocytosis of GABAA Receptors
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015  |   Pubmed ID: 25552561
• Giant Ankyrin-G: a Critical Innovation in Vertebrate Evolution of Fast and Integrated Neuronal Signaling
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015  |   Pubmed ID: 25552556
• Developmental Mechanism of the Periodic Membrane Skeleton in Axons
  ELife. Dec, 2014  |   Pubmed ID: 25535840
• A PIK3C3-ankyrin-B-dynactin Pathway Promotes Axonal Growth and Multiorganelle Transport
  The Journal of Cell Biology. Dec, 2014  |   Pubmed ID: 25533844
• Structural Basis of Diverse Membrane Target Recognitions by Ankyrins
  ELife. Nov, 2014  |   Pubmed ID: 25383926
• A Hierarchy of Ankyrin-spectrin Complexes Clusters Sodium Channels at Nodes of Ranvier
  Nature Neuroscience. Dec, 2014  |   Pubmed ID: 25362473
• Glial Ankyrins Facilitate Paranodal Axoglial Junction Assembly
  Nature Neuroscience. Dec, 2014  |   Pubmed ID: 25362471
• Ankyrin-G Palmitoylation and βII-spectrin Binding to Phosphoinositide Lipids Drive Lateral Membrane Assembly
  The Journal of Cell Biology. Jul, 2014  |   Pubmed ID: 25049274
• Spectrin- and Ankyrin-based Membrane Domains and the Evolution of Vertebrates
  Current Topics in Membranes. 2013  |   Pubmed ID: 24210426
• A Single Divergent Exon Inhibits Ankyrin-B Association with the Plasma Membrane
  The Journal of Biological Chemistry. May, 2013  |   Pubmed ID: 23569209
• E-cadherin Polarity is Determined by a Multifunction Motif Mediating Lateral Membrane Retention Through Ankyrin-G and Apical-lateral Transcytosis Through Clathrin
  The Journal of Biological Chemistry. May, 2013  |   Pubmed ID: 23530049
• Cysteine 70 of Ankyrin-G is S-palmitoylated and is Required for Function of Ankyrin-G in Membrane Domain Assembly
  The Journal of Biological Chemistry. Dec, 2012  |   Pubmed ID: 23129772
• Mutation of Conserved Histidines Alters Tertiary Structure and Nanomechanics of Consensus Ankyrin Repeats
  The Journal of Biological Chemistry. Jun, 2012  |   Pubmed ID: 22514283
• Mechanical Anisotropy of Ankyrin Repeats
  Biophysical Journal. Mar, 2012  |   Pubmed ID: 22404934
• Nanomechanics of Streptavidin Hubs for Molecular Materials
  Advanced Materials (Deerfield Beach, Fla.). Dec, 2011  |   Pubmed ID: 22102445
• Ank3-dependent SVZ Niche Assembly is Required for the Continued Production of New Neurons
  Neuron. Jul, 2011  |   Pubmed ID: 21745638
• Ankyrin-B Interactions with Spectrin and Dynactin-4 Are Required for Dystrophin-based Protection of Skeletal Muscle from Exercise Injury
  The Journal of Biological Chemistry. Mar, 2011  |   Pubmed ID: 21186323
• Full Reconstruction of a Vectorial Protein Folding Pathway by Atomic Force Microscopy and Molecular Dynamics Simulations
  The Journal of Biological Chemistry. Dec, 2010  |   Pubmed ID: 20870713
• Fast and Forceful Refolding of Stretched Alpha-helical Solenoid Proteins
  Biophysical Journal. Jun, 2010  |   Pubmed ID: 20550922
• Cholinergic Augmentation of Insulin Release Requires Ankyrin-B
  Science Signaling. 2010  |   Pubmed ID: 20234002
• Membrane Domains Based on Ankyrin and Spectrin Associated with Cell-cell Interactions
  Cold Spring Harbor Perspectives in Biology. Dec, 2009  |   Pubmed ID: 20457566
• AnkyrinG is Required to Maintain Axo-dendritic Polarity in Vivo
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009  |   Pubmed ID: 19805144
• Ankyrin-based Patterning of Membrane Microdomains: New Insights into a Novel Class of Cardiovascular Diseases
  Journal of Cardiovascular Pharmacology. Aug, 2009  |   Pubmed ID: 19636256
• Ankyrin-G Promotes Cyclic Nucleotide-gated Channel Transport to Rod Photoreceptor Sensory Cilia
  Science (New York, N.Y.). Mar, 2009  |   Pubmed ID: 19299621
• Localization and Structure of the Ankyrin-binding Site on Beta2-spectrin
  The Journal of Biological Chemistry. Mar, 2009  |   Pubmed ID: 19098307
• Ankyrin-B is Required for Coordinated Expression of Beta-2-spectrin, the Na/K-ATPase and the Na/Ca Exchanger in the Inner Segment of Rod Photoreceptors
  Experimental Eye Research. Jan, 2009  |   Pubmed ID: 19007774
• An Ankyrin-based Mechanism for Functional Organization of Dystrophin and Dystroglycan
  Cell. Dec, 2008  |   Pubmed ID: 19109891
• Being There: Cellular Targeting of Voltage-gated Sodium Channels in the Heart
  The Journal of Cell Biology. Jan, 2008  |   Pubmed ID: 18180365
• Organizing the Fluid Membrane Bilayer: Diseases Linked to Spectrin and Ankyrin
  Trends in Molecular Medicine. Jan, 2008  |   Pubmed ID: 18083066
• Adducin Promotes Micrometer-scale Organization of Beta2-spectrin in Lateral Membranes of Bronchial Epithelial Cells
  Molecular Biology of the Cell. Feb, 2008  |   Pubmed ID: 18003973
• Ankyrin-B Syndrome: Enhanced Cardiac Function Balanced by Risk of Cardiac Death and Premature Senescence
  PloS One. Oct, 2007  |   Pubmed ID: 17940615
• Ankyrin-G is a Molecular Partner of E-cadherin in Epithelial Cells and Early Embryos
  The Journal of Biological Chemistry. Sep, 2007  |   Pubmed ID: 17620337
• Ankyrin-G and Beta2-spectrin Collaborate in Biogenesis of Lateral Membrane of Human Bronchial Epithelial Cells
  The Journal of Biological Chemistry. Jan, 2007  |   Pubmed ID: 17074766
• Nanospring Behaviour of Ankyrin Repeats
  Nature. Mar, 2006  |   Pubmed ID: 16415852
• Isoform Specificity of Ankyrin-B: a Site in the Divergent C-terminal Domain is Required for Intramolecular Association
  The Journal of Biological Chemistry. Mar, 2006  |   Pubmed ID: 16368689
• Ankyrin-B Coordinates the Na/K ATPase, Na/Ca Exchanger, and InsP3 Receptor in a Cardiac T-tubule/SR Microdomain
  PLoS Biology. Dec, 2005  |   Pubmed ID: 16292983
• Nav1.5 E1053K Mutation Causing Brugada Syndrome Blocks Binding to Ankyrin-G and Expression of Nav1.5 on the Surface of Cardiomyocytes
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2004  |   Pubmed ID: 15579534
• Ankyrin-B Targets Beta2-spectrin to an Intracellular Compartment in Neonatal Cardiomyocytes
  The Journal of Biological Chemistry. Sep, 2004  |   Pubmed ID: 15262991
• A Cardiac Arrhythmia Syndrome Caused by Loss of Ankyrin-B Function
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004  |   Pubmed ID: 15178757
• Isoform Specificity Among Ankyrins. An Amphipathic Alpha-helix in the Divergent Regulatory Domain of Ankyrin-b Interacts with the Molecular Co-chaperone Hdj1/Hsp40
  The Journal of Biological Chemistry. Jun, 2004  |   Pubmed ID: 15075330
• Lateral Membrane Biogenesis in Human Bronchial Epithelial Cells Requires 190-kDa Ankyrin-G
  The Journal of Biological Chemistry. Apr, 2004  |   Pubmed ID: 14757759
• Inositol 1,4,5-trisphosphate Receptor Localization and Stability in Neonatal Cardiomyocytes Requires Interaction with Ankyrin-B
  The Journal of Biological Chemistry. Mar, 2004  |   Pubmed ID: 14722080
• L1-dependent Neuritogenesis Involves AnkyrinB That Mediates L1-CAM Coupling with Retrograde Actin Flow
  The Journal of Cell Biology. Dec, 2003  |   Pubmed ID: 14657231
• Kv3.1b is a Novel Component of CNS Nodes
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003  |   Pubmed ID: 12805291
• Alpha-adducin Dissociates from F-actin and Spectrin During Platelet Activation
  The Journal of Cell Biology. May, 2003  |   Pubmed ID: 12743105
• Ankyrin-B Mutation Causes Type 4 Long-QT Cardiac Arrhythmia and Sudden Cardiac Death
  Nature. Feb, 2003  |   Pubmed ID: 12571597
• A New Activity of Doublecortin in Recognition of the Phospho-FIGQY Tyrosine in the Cytoplasmic Domain of Neurofascin
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2002  |   Pubmed ID: 12223548
• Ankyrins
  Journal of Cell Science. Apr, 2002  |   Pubmed ID: 11950874
• Developing Nodes of Ranvier Are Defined by Ankyrin-G Clustering and Are Independent of Paranodal Axoglial Adhesion
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2002  |   Pubmed ID: 11842202
• The Ankyrin-B C-terminal Domain Determines Activity of Ankyrin-B/G Chimeras in Rescue of Abnormal Inositol 1,4,5-trisphosphate and Ryanodine Receptor Distribution in Ankyrin-B (-/-) Neonatal Cardiomyocytes
  The Journal of Biological Chemistry. Mar, 2002  |   Pubmed ID: 11781319
• Ankyrin-G Coordinates Assembly of the Spectrin-based Membrane Skeleton, Voltage-gated Sodium Channels, and L1 CAMs at Purkinje Neuron Initial Segments
  The Journal of Cell Biology. Nov, 2001  |   Pubmed ID: 11724816
• LAD-1, the Caenorhabditis Elegans L1CAM Homologue, Participates in Embryonic and Gonadal Morphogenesis and is a Substrate for Fibroblast Growth Factor Receptor Pathway-dependent Phosphotyrosine-based Signaling
  The Journal of Cell Biology. Aug, 2001  |   Pubmed ID: 11502758
• Spectrin and Ankyrin-based Pathways: Metazoan Inventions for Integrating Cells into Tissues
  Physiological Reviews. Jul, 2001  |   Pubmed ID: 11427698
• Ankyrins and Cellular Targeting of Diverse Membrane Proteins to Physiological Sites
  Current Opinion in Cell Biology. Feb, 2001  |   Pubmed ID: 11163135
• Caenorhabditis Elegans Beta-G Spectrin is Dispensable for Establishment of Epithelial Polarity, but Essential for Muscular and Neuronal Function
  The Journal of Cell Biology. May, 2000  |   Pubmed ID: 10811831
• Ankyrin-B is Required for Intracellular Sorting of Structurally Diverse Ca2+ Homeostasis Proteins
  The Journal of Cell Biology. Nov, 1999  |   Pubmed ID: 10579720
• Phosphorylation of Adducin by Rho-kinase Plays a Crucial Role in Cell Motility
  The Journal of Cell Biology. Apr, 1999  |   Pubmed ID: 10209029
• Nervous System Defects of AnkyrinB (-/-) Mice Suggest Functional Overlap Between the Cell Adhesion Molecule L1 and 440-kD AnkyrinB in Premyelinated Axons
  The Journal of Cell Biology. Nov, 1998  |   Pubmed ID: 9832558
• AnkyrinG is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing
  The Journal of Cell Biology. Nov, 1998  |   Pubmed ID: 9832557
• Restriction of 480/270-kD Ankyrin G to Axon Proximal Segments Requires Multiple Ankyrin G-specific Domains
  The Journal of Cell Biology. Sep, 1998  |   Pubmed ID: 9744885
• Adducin is an in Vivo Substrate for Protein Kinase C: Phosphorylation in the MARCKS-related Domain Inhibits Activity in Promoting Spectrin-actin Complexes and Occurs in Many Cells, Including Dendritic Spines of Neurons
  The Journal of Cell Biology. Jul, 1998  |   Pubmed ID: 9679146
• The Phosphorylation State of the FIGQY Tyrosine of Neurofascin Determines Ankyrin-binding Activity and Patterns of Cell Segregation
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 1997  |   Pubmed ID: 9371782
• Morphogenesis of the Node of Ranvier: Co-clusters of Ankyrin and Ankyrin-binding Integral Proteins Define Early Developmental Intermediates
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 1997  |   Pubmed ID: 9278538
• Clustering of Voltage-sensitive Sodium Channels on Axons is Independent of Direct Schwann Cell Contact in the Dystrophic Mouse
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 1997  |   Pubmed ID: 9185545
• Tyrosine Phosphorylation at a Site Highly Conserved in the L1 Family of Cell Adhesion Molecules Abolishes Ankyrin Binding and Increases Lateral Mobility of Neurofascin
  The Journal of Cell Biology. May, 1997  |   Pubmed ID: 9151675
• Common Human ANK2 Variant Confers in Vivo Arrhythmia Phenotypes
  Heart Rhythm.   |   Pubmed ID: 27298202
• Ankyrin-G Coordinates Intercalated Disc Signaling Platform to Regulate Cardiac Excitability in Vivo
  Circulation Research.   |   Pubmed ID: 25239140