Vassiliki A. Boussiotis Division of Hematology-Oncology, Beth Israel Deaconess Medical Center Harvard Medical School Biography Publications Institution JoVE Articles Vassiliki A. Boussiotis has not added a biography. If you are Vassiliki A. Boussiotis and would like to personalize this page please email our Author Liaison for assistance. Publications Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy Frontiers in Oncology. Month, 2018 | Pubmed ID: 30123774 Publisher Correction: Feeling Stressed? It Might Be Your T Cells Nature Immunology. Sep, 2018 | Pubmed ID: 29955108 Possible Reactivation of Chromosomally Integrated Human Herpesvirus 6 After Treatment with Histone Deacetylase Inhibitor Blood Advances. Jun, 2018 | Pubmed ID: 29898877 Immunotherapies for Malignant Glioma Oncogene. Mar, 2018 | Pubmed ID: 29242608 Feeling Stressed? It Might Be Your T Cells Nature Immunology. Nov, 2017 | Pubmed ID: 29144505 The Adaptor Molecule RIAM Integrates Signaling Events Critical for Integrin-mediated Control of Immune Function and Cancer Progression Science Signaling. Aug, 2017 | Pubmed ID: 28831022 Advances in the Pathophysiology and Treatment of Relapsed/refractory Hodgkin's Lymphoma with an Emphasis on Targeted Therapies and Transplantation Strategies Blood and Lymphatic Cancer : Targets and Therapy. Month, 2017 | Pubmed ID: 28701859 Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses Frontiers in Immunology. Month, 2017 | Pubmed ID: 28443090 Angiogenic Factors Correlate with T Cell Immune Reconstitution and Clinical Outcomes After Double-Unit Umbilical Cord Blood Transplantation in Adults Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. 01, 2017 | Pubmed ID: 27777141 JAK3-mediated Phosphorylation of EZH2: a Novel Mechanism of Non-canonical EZH2 Activation and Oncogenic Function Translational Cancer Research. Nov, 2016 | Pubmed ID: 28868240 The Role of Metabolic Reprogramming in T Cell Fate and Function Current Trends in Immunology. Month, 2016 | Pubmed ID: 28356677 The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation Frontiers in Immunology. Month, 2016 | Pubmed ID: 28018338 Epigenetic Regulation of Cancer Biology and Anti-tumor Immunity by EZH2 Oncotarget. Dec, 2016 | Pubmed ID: 27793053 Corrigendum: Regulation of T Cell Differentiation and Function by EZH2 Frontiers in Immunology. Month, 2016 | Pubmed ID: 27648006 Clinical Significance of T Cell Metabolic Reprogramming in Cancer Clinical and Translational Medicine. Dec, 2016 | Pubmed ID: 27510264 Regulation of T Cell Differentiation and Function by EZH2 Frontiers in Immunology. Month, 2016 | Pubmed ID: 27199994 Cell-specific PD-L1 Expression in DLBCL Blood. Nov, 2015 | Pubmed ID: 26542250 PD-1 Alters T-cell Metabolic Reprogramming by Inhibiting Glycolysis and Promoting Lipolysis and Fatty Acid Oxidation Nature Communications. Mar, 2015 | Pubmed ID: 25809635 Somatic Mutations and Immunotherapy Outcome with CTLA-4 Blockade in Melanoma The New England Journal of Medicine. Dec, 2014 | Pubmed ID: 25409261 The Role of the Thymus in T-cell Immune Reconstitution After Umbilical Cord Blood Transplantation Blood. Nov, 2014 | Pubmed ID: 25287708 Biochemical Signaling of PD-1 on T Cells and Its Functional Implications Cancer Journal (Sudbury, Mass.). Jul-Aug, 2014 | Pubmed ID: 25098287 The Cyclin Dependent Kinase Inhibitor (R)-roscovitine Mediates Selective Suppression of Alloreactive Human T Cells but Preserves Pathogen-specific and Leukemia-specific Effectors Clinical Immunology (Orlando, Fla.). May-Jun, 2014 | Pubmed ID: 24631965 The Role of IL-17-producing Foxp3+ CD4+ T Cells in Inflammatory Bowel Disease and Colon Cancer Clinical Immunology (Orlando, Fla.). Aug, 2013 | Pubmed ID: 23773923 PD-1 Increases PTEN Phosphatase Activity While Decreasing PTEN Protein Stability by Inhibiting Casein Kinase 2 Molecular and Cellular Biology. Aug, 2013 | Pubmed ID: 23732914 RIAM (Rap1-interacting Adaptor Molecule) Regulates Complement-dependent Phagocytosis Cellular and Molecular Life Sciences : CMLS. Jul, 2013 | Pubmed ID: 23420480 Rap1-interacting Adapter Molecule (RIAM) Associates with the Plasma Membrane Via a Proximity Detector The Journal of Cell Biology. Oct, 2012 | Pubmed ID: 23045549 PD-1 Inhibits T Cell Proliferation by Upregulating P27 and P15 and Suppressing Cdc25A Cell Cycle (Georgetown, Tex.). Dec, 2012 | Pubmed ID: 23032366 Runx1 and Runx3 Are Involved in the Generation and Function of Highly Suppressive IL-17-producing T Regulatory Cells PloS One. Month, 2012 | Pubmed ID: 22984619 Selective Effects of PD-1 on Akt and Ras Pathways Regulate Molecular Components of the Cell Cycle and Inhibit T Cell Proliferation Science Signaling. Jun, 2012 | Pubmed ID: 22740686 Molecular and Functional Heterogeneity of T Regulatory Cells Clinical Immunology (Orlando, Fla.). Dec, 2011 | Pubmed ID: 21945485 Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21454517 Rap1A Regulates Generation of T Regulatory Cells Via LFA-1-dependent and LFA-1-independent Mechanisms Cellular Immunology. Month, 2010 | Pubmed ID: 20864093 IL-1β-mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-producing Cells Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010 | Pubmed ID: 20817874 RIAM Regulates the Cytoskeletal Distribution and Activation of PLC-gamma1 in T Cells Science Signaling. Dec, 2009 | Pubmed ID: 19952372 The Cyclin Dependent Kinase Inhibitor (R)-roscovitine Prevents Alloreactive T Cell Clonal Expansion and Protects Against Acute GvHD Cell Cycle (Georgetown, Tex.). Jun, 2009 | Pubmed ID: 19448431 Tob, a Member of the APRO Family, Regulates Immunological Quiescence and Tumor Suppression Cell Cycle (Georgetown, Tex.). Apr, 2009 | Pubmed ID: 19270514 Interleukin-4 Stimulates Proliferation and Growth of T-cell Acute Lymphoblastic Leukemia Cells by Activating MTOR Signaling Leukemia. Jan, 2009 | Pubmed ID: 18596736 The Nore1B/Mst1 Complex Restrains Antigen Receptor-induced Proliferation of Naïve T Cells Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19073936 Control and Regulation of Peripheral Tolerance in Allergic Inflammatory Disease: Therapeutic Consequences Chemical Immunology and Allergy. Month, 2008 | Pubmed ID: 18802347 CD134-allodepletion Allows Selective Elimination of Alloreactive Human T Cells Without Loss of Virus-specific and Leukemia-specific Effectors Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. May, 2008 | Pubmed ID: 18410894 Umbilical Cord Blood Transplantation: Basic Biology and Clinical Challenges to Immune Reconstitution Clinical Immunology (Orlando, Fla.). Jun, 2008 | Pubmed ID: 18395491 Twisted Gastrulation (Tsg) is Regulated by Tob and Enhances TGF-beta Signaling in Activated T Lymphocytes Blood. Apr, 2007 | Pubmed ID: 17164348 A Pathway Regulated by Cell Cycle Inhibitor P27Kip1 and Checkpoint Inhibitor Smad3 is Involved in the Induction of T Cell Tolerance Nature Immunology. Nov, 2006 | Pubmed ID: 17013388 Physiologic Regulation of Central and Peripheral T Cell Tolerance: Lessons for Therapeutic Applications Journal of Molecular Medicine (Berlin, Germany). Nov, 2006 | Pubmed ID: 16972086 CD28 Costimulation Mediates Transcription of SKP2 and CKS1, the Substrate Recognition Components of SCFSkp2 Ubiquitin Ligase That Leads P27kip1 to Degradation Cell Cycle (Georgetown, Tex.). Sep, 2006 | Pubmed ID: 16969077 Rap1 Regulation of RIAM and Cell Adhesion Methods in Enzymology. Month, 2006 | Pubmed ID: 16757337 Rap1-GTP is a Negative Regulator of Th Cell Function and Promotes the Generation of CD4+CD103+ Regulatory T Cells in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2005 | Pubmed ID: 16116203 CD4+CD25+ Regulatory T-cell Lines from Human Cord Blood Have Functional and Molecular Properties of T-cell Anergy Blood. Nov, 2005 | Pubmed ID: 16020508 Common Gamma Chain-signaling Cytokines Promote Proliferation of T-cell Acute Lymphoblastic Leukemia Haematologica. Dec, 2004 | Pubmed ID: 15590396 RIAM, an Ena/VASP and Profilin Ligand, Interacts with Rap1-GTP and Mediates Rap1-induced Adhesion Developmental Cell. Oct, 2004 | Pubmed ID: 15469846 Activation of PI3K is Indispensable for Interleukin 7-mediated Viability, Proliferation, Glucose Use, and Growth of T Cell Acute Lymphoblastic Leukemia Cells The Journal of Experimental Medicine. Sep, 2004 | Pubmed ID: 15353558 IL-7-dependent Human Leukemia T-cell Line As a Valuable Tool for Drug Discovery in T-ALL Blood. Mar, 2004 | Pubmed ID: 14615384 Antigen-specific and Persistent Tuberculin Anergy in a Cohort of Pulmonary Tuberculosis Patients from Rural Cambodia Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12032325 CD28 Costimulation Mediates Down-regulation of P27kip1 and Cell Cycle Progression by Activation of the PI3K/PKB Signaling Pathway in Primary Human T Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002 | Pubmed ID: 11884439 Blockade of B7/CD28 in Mixed Lymphocyte Reaction Cultures Results in the Generation of Alternatively Activated Macrophages, Which Suppress T-cell Responses Blood. Feb, 2002 | Pubmed ID: 11830501 CTLA-4 Regulates Cell Cycle Progression During a Primary Immune Response European Journal of Immunology. 02, 2002 | Pubmed ID: 11807776 Ontrafeling van de hoofdrolspelers van de Humorale immuniteit: geavanceerde en geoptimaliseerd lymfocyt isolatie Protocol van RattenUitrustingen Peyer van Patches Yavuz F. Yazicioglu1,2, Halil I. Aksoylar1,2, Rinku Pal1,2, Nikolaos Patsoukis1,2, Vassiliki A. Boussiotis1,2 1Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, 2Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School JoVE 58490 Cancer Research
Ontrafeling van de hoofdrolspelers van de Humorale immuniteit: geavanceerde en geoptimaliseerd lymfocyt isolatie Protocol van RattenUitrustingen Peyer van Patches Yavuz F. Yazicioglu1,2, Halil I. Aksoylar1,2, Rinku Pal1,2, Nikolaos Patsoukis1,2, Vassiliki A. Boussiotis1,2 1Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, 2Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School JoVE 58490 Cancer Research