Walter N. Hittelman

Publications

• Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination
  Stem Cell Reports. Oct, 2017  |   Pubmed ID: 29103969
• Replication Stress Leading to Apoptosis Within the S-phase Contributes to Synergism Between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2017  |   Pubmed ID: 28790110
• Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells
  Cancer Research. 06, 2016  |   Pubmed ID: 27197148
• Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain
  Cell Reports. 05, 2016  |   Pubmed ID: 27160909
• Pannexin-1 Up-regulation in the Dorsal Root Ganglion Contributes to Neuropathic Pain Development
  The Journal of Biological Chemistry. Jun, 2015  |   Pubmed ID: 25925949
• MOF Phosphorylation by ATM Regulates 53BP1-mediated Double-strand Break Repair Pathway Choice
  Cell Reports. Jul, 2014  |   Pubmed ID: 24953651
• Antagonism of Tumoral Prolactin Receptor Promotes Autophagy-related Cell Death
  Cell Reports. Apr, 2014  |   Pubmed ID: 24703838
• The Functionalized Human Serine Protease Granzyme B/VEGF₁₂₁ Targets Tumor Vasculature and Ablates Tumor Growth
  Molecular Cancer Therapeutics. Oct, 2013  |   Pubmed ID: 23858102
• Antitumor Activity of a Humanized, Bivalent Immunotoxin Targeting Fn14-positive Solid Tumors
  Cancer Research. Jul, 2013  |   Pubmed ID: 23722548
• Construction and Characterization of Novel, Completely Human Serine Protease Therapeutics Targeting Her2/neu
  Molecular Cancer Therapeutics. Jun, 2013  |   Pubmed ID: 23493312
• Programming in Situ Immunofluorescence Intensities Through Interchangeable Reactions of Dynamic DNA Complexes
  Chembiochem : a European Journal of Chemical Biology. Dec, 2012  |   Pubmed ID: 23165916
• Prevention of Paclitaxel-induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System
  Anesthesia and Analgesia. May, 2012  |   Pubmed ID: 22392969
• Development and Characterization of a Potent Immunoconjugate Targeting the Fn14 Receptor on Solid Tumor Cells
  Molecular Cancer Therapeutics. Jul, 2011  |   Pubmed ID: 21586630
• Prevention of Bronchial Hyperplasia by EGFR Pathway Inhibitors in an Organotypic Culture Model
  Cancer Prevention Research (Philadelphia, Pa.). Aug, 2011  |   Pubmed ID: 21505178
• Are Cancer Stem Cells Radioresistant?
  Future Oncology (London, England). Oct, 2010  |   Pubmed ID: 21062156
• Characterization and Mechanistic Studies of a Novel Melanoma-targeting Construct Containing IκBa for Specific Inhibition of Nuclear Factor-κB Activity
  Neoplasia (New York, N.Y.). Oct, 2010  |   Pubmed ID: 20927315
• Proliferative Changes in the Bronchial Epithelium of Former Smokers Treated with Retinoids
  Journal of the National Cancer Institute. Nov, 2007  |   Pubmed ID: 17971525
• Deficiency of Cell Cycle Checkpoints and DNA Repair System Predispose Individuals to Esophageal Cancer
  Mutation Research. Dec, 2006  |   Pubmed ID: 17011594
• Disruption of the Rad9/Rad1/Hus1 (9-1-1) Complex Leads to Checkpoint Signaling and Replication Defects
  Oncogene. Jul, 2004  |   Pubmed ID: 15184880
• Improvement and Application of Fluorescence Inter-simple Sequence Repeat Polymerase Chain Reaction for the Study of Subclonal Growths in Lung Epithelial Cell Populations
  Chest. May, 2004  |   Pubmed ID: 15136450
• Paclitaxel Induces Inactivation of P70 S6 Kinase and Phosphorylation of Thr421 and Ser424 Via Multiple Signaling Pathways in Mitosis
  Oncogene. Jan, 2003  |   Pubmed ID: 12555062
• Biologic Correlates of a Biochemoprevention Trial in Advanced Upper Aerodigestive Tract Premalignant Lesions
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Dec, 2002  |   Pubmed ID: 12496051
• Genetic Instability in Epithelial Tissues at Risk for Cancer
  Annals of the New York Academy of Sciences. Dec, 2001  |   Pubmed ID: 11795428