Wei-Jun Qian Integrative Omics, Biological Sciences Division Pacific Northwest National Laboratory Biography Publications Institution JoVE Articles Wei-Jun Qian has not added a biography. If you are Wei-Jun Qian and would like to personalize this page please email our Author Liaison for assistance. Publications Assessment of TMT Labeling Efficiency in Large-Scale Quantitative Proteomics: The Critical Effect of Sample PH ACS Omega. May, 2021 | Pubmed ID: 34056417 Repetitive Diacetyl Vapor Exposure Promotes Ubiquitin Proteasome Stress and Precedes Bronchiolitis Obliterans Pathology Archives of Toxicology. May, 2021 | Pubmed ID: 34031698 Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes Diabetes. May, 2021 | Pubmed ID: 33947721 A Comprehensive Urine Proteome Database Generated From Patients With Various Renal Conditions and Prostate Cancer Frontiers in Medicine. 2021 | Pubmed ID: 33928097 Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss Journal of Proteome Research. 05, 2021 | Pubmed ID: 33900085 Enhancing Top-Down Proteomics of Brain Tissue with FAIMS Journal of Proteome Research. 05, 2021 | Pubmed ID: 33856812 Stoichiometric Thiol Redox Proteomics for Quantifying Cellular Responses to Perturbations Antioxidants (Basel, Switzerland). Mar, 2021 | Pubmed ID: 33807006 Defective Insulin Receptor Signaling in HPSCs Skews Pluripotency and Negatively Perturbs Neural Differentiation The Journal of Biological Chemistry. Mar, 2021 | Pubmed ID: 33667549 Surfactant-assisted One-pot Sample Preparation for Label-free Single-cell Proteomics Communications Biology. Mar, 2021 | Pubmed ID: 33649493 Enhancement of Polyhydroxyalkanoate Production by Co-feeding Lignin Derivatives with Glycerol in Pseudomonas Putida KT2440 Biotechnology for Biofuels. Jan, 2021 | Pubmed ID: 33413621 Characterization of Cellular Oxidative Stress Response by Stoichiometric Redox Proteomics American Journal of Physiology. Cell Physiology. 02, 2021 | Pubmed ID: 33264075 Meta-analysis of Peptides to Detect Protein Significance Statistics and Its Interface. 2020 | Pubmed ID: 34055134 Corrigendum: Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney Frontiers in Medicine. 2020 | Pubmed ID: 33511148 Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells Cell Systems. Oct, 2020 | Pubmed ID: 33113355 Protein Thiol Oxidation in the Rat Lung Following E-cigarette Exposure Redox Biology. Oct, 2020 | Pubmed ID: 33080441 Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney Frontiers in Medicine. 2020 | Pubmed ID: 33072769 Stochiometric Quantification of the Thiol Redox Proteome of Macrophages Reveals Subcellular Compartmentalization and Susceptibility to Oxidative Perturbations Redox Biology. Sep, 2020 | Pubmed ID: 32750668 Proteomic Tissue-Based Classifier for Early Prediction of Prostate Cancer Progression Cancers. May, 2020 | Pubmed ID: 32429558 Block Design with Common Reference Samples Enables Robust Large-Scale Label-Free Quantitative Proteome Profiling Journal of Proteome Research. 07, 2020 | Pubmed ID: 32407631 Development of Multiplexed Immuno-N-Terminomics to Reveal the Landscape of Proteolytic Processing in Early Embryogenesis of Analytical Chemistry. 04, 2020 | Pubmed ID: 32196314 Accurate Identification of Deamidation and Citrullination from Global Shotgun Proteomics Data Using a Dual-Search Delta Score Strategy Journal of Proteome Research. 04, 2020 | Pubmed ID: 32175737 Evaluation of the Cytotoxic and Cellular Proteome Impacts of Food-grade TiO (E171) Using Simulated Gastrointestinal Digestions and a Tri-culture Small Intestinal Epithelial Model NanoImpact. Jan, 2020 | Pubmed ID: 32133427 A Proteome-wide Assessment of the Oxidative Stress Paradigm for Metal and Metal-oxide Nanomaterials in Human Macrophages NanoImpact. Jan, 2020 | Pubmed ID: 32133426 Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 As a Target for Type 1 Diabetes Intervention Cell Metabolism. 02, 2020 | Pubmed ID: 31928885 High-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform Analytical Chemistry. 10, 2019 | Pubmed ID: 31509397 Increased β-cell Proliferation Before Immune Cell Invasion Prevents Progression of Type 1 Diabetes Nature Metabolism. May, 2019 | Pubmed ID: 31423480 Automated Nanoflow Two-Dimensional Reversed-Phase Liquid Chromatography System Enables In-Depth Proteome and Phosphoproteome Profiling of Nanoscale Samples Analytical Chemistry. 08, 2019 | Pubmed ID: 31241912 The Role of Proteomics in Assessing Beta-cell Dysfunction and Death in Type 1 Diabetes Expert Review of Proteomics. 07, 2019 | Pubmed ID: 31232620 Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance Radiation Research. 08, 2019 | Pubmed ID: 31141469 Response to Comment on Sims Et Al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264 Diabetes Care. 05, 2019 | Pubmed ID: 31010952 Architecture and Subunit Arrangement of Native AMPA Receptors Elucidated by Cryo-EM Science (New York, N.Y.). 04, 2019 | Pubmed ID: 30975770 Discovery of Potential Pathways for Biological Conversion of Poplar Wood into Lipids by Co-fermentation of Strains Biotechnology for Biofuels. 2019 | Pubmed ID: 30923568 Boosting to Amplify Signal with Isobaric Labeling (BASIL) Strategy for Comprehensive Quantitative Phosphoproteomic Characterization of Small Populations of Cells Analytical Chemistry. May, 2019 | Pubmed ID: 30843680 Improving Mitochondrial Function with SS-31 Reverses Age-related Redox Stress and Improves Exercise Tolerance in Aged Mice Free Radical Biology & Medicine. 04, 2019 | Pubmed ID: 30597195 Carrier-Assisted Single-Tube Processing Approach for Targeted Proteomics Analysis of Low Numbers of Mammalian Cells Analytical Chemistry. 01, 2019 | Pubmed ID: 30557009 Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes Diabetes Care. 02, 2019 | Pubmed ID: 30530850 Genomics and Biochemistry Investigation on the Metabolic Pathway of Milled Wood and Alkali Lignin-derived Aromatic Metabolites of SP-35 Biotechnology for Biofuels. 2018 | Pubmed ID: 30603046 Nanoproteomics Comes of Age Expert Review of Proteomics. 11, 2018 | Pubmed ID: 30375896 Insulin Receptor-mediated Signaling Regulates Pluripotency Markers and Lineage Differentiation Molecular Metabolism. 12, 2018 | Pubmed ID: 30316806 Facile Carrier-assisted Targeted Mass Spectrometric Approach for Proteomic Analysis of Low Numbers of Mammalian Cells Communications Biology. 2018 | Pubmed ID: 30271983 Nanowell-mediated Two-dimensional Liquid Chromatography Enables Deep Proteome Profiling of <1000 Mammalian Cells Chemical Science. Sep, 2018 | Pubmed ID: 30210768 Serum Biomarkers for Diagnosis and Prediction of Type 1 Diabetes Translational Research : the Journal of Laboratory and Clinical Medicine. 11, 2018 | Pubmed ID: 30144424 Mass Spectrometry-based Proteomics for System-level Characterization of Biological Responses to Engineered Nanomaterials Analytical and Bioanalytical Chemistry. Sep, 2018 | Pubmed ID: 29947897 Spatially Resolved Proteome Mapping of Laser Capture Microdissected Tissue with Automated Sample Transfer to Nanodroplets Molecular & Cellular Proteomics : MCP. Sep, 2018 | Pubmed ID: 29941660 Fatiguing Contractions Increase Protein S-glutathionylation Occupancy in Mouse Skeletal Muscle Redox Biology. 07, 2018 | Pubmed ID: 29857311 Urinary Virome Perturbations in Kidney Transplantation Frontiers in Medicine. 2018 | Pubmed ID: 29725592 Optimization for Peptide Sample Preparation for Urine Peptidomics Methods in Molecular Biology (Clifton, N.J.). Apr, 2018 | Pubmed ID: 29623538 Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway Analytical Chemistry. 04, 2018 | Pubmed ID: 29584399 Subnanogram Proteomics: Impact of LC Column Selection, MS Instrumentation and Data Analysis Strategy on Proteome Coverage for Trace Samples International Journal of Mass Spectrometry. Apr, 2018 | Pubmed ID: 29576737 Nanodroplet Processing Platform for Deep and Quantitative Proteome Profiling of 10-100 Mammalian Cells Nature Communications. 02, 2018 | Pubmed ID: 29491378 Multiplexed Targeted Mass Spectrometry Assays for Prostate Cancer-associated Urinary Proteins Oncotarget. Nov, 2017 | Pubmed ID: 29254211 LC-SRM-Based Targeted Quantification of Urinary Protein Biomarkers Methods in Molecular Biology (Clifton, N.J.). Nov, 2017 | Pubmed ID: 29116567 -Nitrosylation Inhibits the Kinase Activity of Tomato Phosphoinositide-dependent Kinase 1 (PDK1) The Journal of Biological Chemistry. 12, 2017 | Pubmed ID: 28972151 Functional Enzyme-Based Approach for Linking Microbial Community Functions with Biogeochemical Process Kinetics Environmental Science & Technology. Oct, 2017 | Pubmed ID: 28891285 Quantification of Mutant SPOP Proteins in Prostate Cancer Using Mass Spectrometry-based Targeted Proteomics Journal of Translational Medicine. Aug, 2017 | Pubmed ID: 28810879 Advances in Microscale Separations Towards Nanoproteomics Applications Journal of Chromatography. A. Nov, 2017 | Pubmed ID: 28765000 Deep-Dive Targeted Quantification for Ultrasensitive Analysis of Proteins in Nondepleted Human Blood Plasma/Serum and Tissues Analytical Chemistry. Sep, 2017 | Pubmed ID: 28724286 Targeted Proteomic Assays for Quantitation of Proteins Identified by Proteogenomic Analysis of Ovarian Cancer Scientific Data. 07, 2017 | Pubmed ID: 28722704 Quantitative Proteomics Identifies Altered O-GlcNAcylation of Structural, Synaptic and Memory-associated Proteins in Alzheimer's Disease The Journal of Pathology. Sep, 2017 | Pubmed ID: 28657654 Targeted Quantification of Functional Enzyme Dynamics in Environmental Samples for Microbially Mediated Biogeochemical Processes Environmental Microbiology Reports. Oct, 2017 | Pubmed ID: 28618201 Quantitative Proteomic Characterization of Redox-dependent Post-translational Modifications on Protein Cysteines Molecular BioSystems. May, 2017 | Pubmed ID: 28357434 Biodegradation of Alkaline Lignin by L1 Biotechnology for Biofuels. 2017 | Pubmed ID: 28239416 An Efficient Method for Native Protein Purification in the Selected Range from Prostate Cancer Tissue Digests Chinese Clinical Oncology. Dec, 2016 | Pubmed ID: 28061542 Conservation of Protein Abundance Patterns Reveals the Regulatory Architecture of the EGFR-MAPK Pathway Science Signaling. 07, 2016 | Pubmed ID: 27405981 Advances in Targeted Proteomics and Applications to Biomedical Research Proteomics. 08, 2016 | Pubmed ID: 27302376 Mining the Human Urine Proteome for Monitoring Renal Transplant Injury Kidney International. 06, 2016 | Pubmed ID: 27165815 The Current State of the Art of Quantitative Phosphoproteomics and Its Applications to Diabetes Research Expert Review of Proteomics. 2016 | Pubmed ID: 26960075 9-Fluorenylmethyl (Fm) Disulfides: Biomimetic Precursors for Persulfides Organic Letters. Mar, 2016 | Pubmed ID: 26870874 Contributions of Immunoaffinity Chromatography to Deep Proteome Profiling of Human Biofluids Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. May, 2016 | Pubmed ID: 26868616 Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26867747 SNaPP: Simplified Nanoproteomics Platform for Reproducible Global Proteomic Analysis of Nanogram Protein Quantities Endocrinology. Mar, 2016 | Pubmed ID: 26745641 Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays Clinical Chemistry. Jan, 2016 | Pubmed ID: 26719571 SerpinB1 Promotes Pancreatic β Cell Proliferation Cell Metabolism. Jan, 2016 | Pubmed ID: 26701651 Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-Dependent Regulation of Macrophage Function During Nanoparticle-Induced Oxidative Stress ACS Nano. Jan, 2016 | Pubmed ID: 26700264 The Clinical Impact of Recent Advances in LC-MS for Cancer Biomarker Discovery and Verification Expert Review of Proteomics. 2016 | Pubmed ID: 26581546 The Measurement of Reversible Redox Dependent Post-translational Modifications and Their Regulation of Mitochondrial and Skeletal Muscle Function Frontiers in Physiology. 2015 | Pubmed ID: 26635632 Preserved DNA Damage Checkpoint Pathway Protects Against Complications in Long-Standing Type 1 Diabetes Cell Metabolism. Aug, 2015 | Pubmed ID: 26244933 Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics Journal of Proteome Research. Aug, 2015 | Pubmed ID: 26151086 Analytical Platform Evaluation for Quantification of ERG in Prostate Cancer Using Protein and MRNA Detection Methods Journal of Translational Medicine. Feb, 2015 | Pubmed ID: 25889691 Sensitive Targeted Quantification of ERK Phosphorylation Dynamics and Stoichiometry in Human Cells Without Affinity Enrichment Analytical Chemistry. Jan, 2015 | Pubmed ID: 25517423 The Identification of Novel Potential Injury Mechanisms and Candidate Biomarkers in Renal Allograft Rejection by Quantitative Proteomics Molecular & Cellular Proteomics : MCP. Feb, 2014 | Pubmed ID: 33498143 Perturbations in the Urinary Exosome in Transplant Rejection Frontiers in Medicine. 2014 | Pubmed ID: 25593928 Proteomic Approaches for Site-specific O-GlcNAcylation Analysis Bioanalysis. 2014 | Pubmed ID: 25411699 Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism Cell Metabolism. Nov, 2014 | Pubmed ID: 25307860 Antibody-independent Targeted Quantification of TMPRSS2-ERG Fusion Protein Products in Prostate Cancer Molecular Oncology. Oct, 2014 | Pubmed ID: 25266362 Expediting SRM Assay Development for Large-scale Targeted Proteomics Experiments Journal of Proteome Research. Oct, 2014 | Pubmed ID: 25145539 A Method to Determine Lysine Acetylation Stoichiometries International Journal of Proteomics. 2014 | Pubmed ID: 25143833 Proteome-wide Light/dark Modulation of Thiol Oxidation in Cyanobacteria Revealed by Quantitative Site-specific Redox Proteomics Molecular & Cellular Proteomics : MCP. Dec, 2014 | Pubmed ID: 25118246 Detecting Differential Protein Expression in Large-scale Population Proteomics Bioinformatics (Oxford, England). Oct, 2014 | Pubmed ID: 24928210 High and Low Doses of Ionizing Radiation Induce Different Secretome Profiles in a Human Skin Model PloS One. 2014 | Pubmed ID: 24642900 Optimization for Peptide Sample Preparation for Urine Peptidomics Clinical Proteomics. Feb, 2014 | Pubmed ID: 24568099 Resin-assisted Enrichment of Thiols As a General Strategy for Proteomic Profiling of Cysteine-based Reversible Modifications Nature Protocols. Jan, 2014 | Pubmed ID: 24336471 The Identification of Novel Potential Injury Mechanisms and Candidate Biomarkers in Renal Allograft Rejection by Quantitative Proteomics Molecular & Cellular Proteomics : MCP. Feb, 2014 | Pubmed ID: 24335474 Proteomic Identification and Quantification of S-glutathionylation in Mouse Macrophages Using Resin-assisted Enrichment and Isobaric Labeling Free Radical Biology & Medicine. Feb, 2014 | Pubmed ID: 24333276 A Highly Sensitive Targeted Mass Spectrometric Assay for Quantification of AGR2 Protein in Human Urine and Serum Journal of Proteome Research. Feb, 2014 | Pubmed ID: 24251762 Impact of Alg3 Gene Deletion on Growth, Development, Pigment Production, Protein Secretion, and Functions of Recombinant Trichoderma Reesei Cellobiohydrolases in Aspergillus Niger Fungal Genetics and Biology : FG & B. Dec, 2013 | Pubmed ID: 24076077 Long-gradient Separations Coupled with Selected Reaction Monitoring for Highly Sensitive, Large Scale Targeted Protein Quantification in a Single Analysis Analytical Chemistry. Oct, 2013 | Pubmed ID: 24004026 Resin-assisted Enrichment of N-terminal Peptides for Characterizing Proteolytic Processing Analytical Chemistry. Jul, 2013 | Pubmed ID: 23772796 Targeted Quantification of Low Ng/mL Level Proteins in Human Serum Without Immunoaffinity Depletion Journal of Proteome Research. Jul, 2013 | Pubmed ID: 23763644 Evaluation of Selected Binding Domains for the Analysis of Ubiquitinated Proteomes Journal of the American Society for Mass Spectrometry. Aug, 2013 | Pubmed ID: 23649778 Trauma-associated Human Neutrophil Alterations Revealed by Comparative Proteomics Profiling Proteomics. Clinical Applications. Aug, 2013 | Pubmed ID: 23589343 Determination of Burn Patient Outcome by Large-scale Quantitative Discovery Proteomics Critical Care Medicine. Jun, 2013 | Pubmed ID: 23507713 Synthesis and Application of an Environmentally Insensitive Cy3-based Arsenical Fluorescent Probe to Identify Adaptive Microbial Responses Involving Proximal Dithiol Oxidation Journal of the American Chemical Society. Mar, 2013 | Pubmed ID: 23379730 Mit Dem Leber-abgeleitete Systemische Faktoren β Zellen Hyperplasie Insulinresistenz Staaten Cell Reports. Jan, 2013 | Pubmed ID: 23375376 In-source Fragmentation and the Sources of Partially Tryptic Peptides in Shotgun Proteomics Journal of Proteome Research. Feb, 2013 | Pubmed ID: 23268687 Quantitative Standortspezifische Reaktivität Profilierung Von S-Nitrosylation in Der Maus Skelettmuskulatur Mit Cysteinyl Peptid-Anreicherung Gekoppelt Mit Massenspektrometrie Free Radical Biology & Medicine. Dec, 2012 | Pubmed ID: 23277143 Antibody-free, Targeted Mass-spectrometric Approach for Quantification of Proteins at Low Picogram Per Milliliter Levels in Human Plasma/serum Proceedings of the National Academy of Sciences of the United States of America. Sep, 2012 | Pubmed ID: 22949669 Analysis of Serum Total and Free PSA Using Immunoaffinity Depletion Coupled to SRM: Correlation with Clinical Immunoassay Tests Journal of Proteomics. Aug, 2012 | Pubmed ID: 22846433 Advancing the Sensitivity of Selected Reaction Monitoring-based Targeted Quantitative Proteomics Proteomics. Apr, 2012 | Pubmed ID: 22577010 Identification of Phosphorylated Butyrylcholinesterase in Human Plasma Using Immunoaffinity Purification and Mass Spectrometry Analytica Chimica Acta. Apr, 2012 | Pubmed ID: 22444575 Simple Sodium Dodecyl Sulfate-assisted Sample Preparation Method for LC-MS-based Proteomics Applications Analytical Chemistry. Mar, 2012 | Pubmed ID: 22339560 Mapping N-linked Glycosylation Sites in the Secretome and Whole Cells of Aspergillus Niger Using Hydrazide Chemistry and Mass Spectrometry Journal of Proteome Research. Jan, 2012 | Pubmed ID: 22136231 IgY14 and SuperMix Immunoaffinity Separations Coupled with Liquid Chromatography-mass Spectrometry for Human Plasma Proteomics Biomarker Discovery Methods (San Diego, Calif.). Feb, 2012 | Pubmed ID: 21925605 18O-labeled Proteome Reference As Global Internal Standards for Targeted Quantification by Selected Reaction Monitoring-mass Spectrometry Molecular & Cellular Proteomics : MCP. Dec, 2011 | Pubmed ID: 21988777 Quantitative Proteomics Analysis of Adsorbed Plasma Proteins Classifies Nanoparticles with Different Surface Properties and Size Proteomics. Dec, 2011 | Pubmed ID: 21956884 Unraveling Pancreatic Islet Biology by Quantitative Proteomics Expert Review of Proteomics. Aug, 2011 | Pubmed ID: 21819304 Identification of C-type Heme-containing Peptides Using Nonactivated Immobilized Metal Affinity Chromatography Resin Enrichment and Higher-energy Collisional Dissociation Analytical Chemistry. Oct, 2011 | Pubmed ID: 21740036 Liquid Chromatography-mass Spectrometry-based Quantitative Proteomics The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21632532 Trypsin-catalyzed Oxygen-18 Labeling for Quantitative Proteomics Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21604114 Enhanced Sensitivity for Selected Reaction Monitoring Mass Spectrometry-based Targeted Proteomics Using a Dual Stage Electrodynamic Ion Funnel Interface Molecular & Cellular Proteomics : MCP. Feb, 2011 | Pubmed ID: 20410378 Improved LC-MS/MS Spectral Counting Statistics by Recovering Low-scoring Spectra Matched to Confidently Identified Peptide Sequences Journal of Proteome Research. Nov, 2010 | Pubmed ID: 20812748 Klinische Biochips Für Neutrophil Genomik Und Proteomik Nature Medicine. Sep, 2010 | Pubmed ID: 20802500 Plasma Proteome Response to Severe Burn Injury Revealed by 18O-labeled "universal" Reference-based Quantitative Proteomics Journal of Proteome Research. Sep, 2010 | Pubmed ID: 20698492 CD90/THY1 is Overexpressed in Prostate Cancer-associated Fibroblasts and Could Serve As a Cancer Biomarker Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Oct, 2010 | Pubmed ID: 20562849 Shotgun Proteomics Identifies Proteins Specific for Acute Renal Transplant Rejection Proteomics. Clinical Applications. Jan, 2010 | Pubmed ID: 20543976 Sensible Immunoassays Von Nitrierte Fibrinogen in Menschlichen Hinter Talanta. Jun, 2010 | Pubmed ID: 20441955 Quantitative Analysis of Cell Surface Membrane Proteins Using Membrane-impermeable Chemical Probe Coupled with 18O Labeling Journal of Proteome Research. May, 2010 | Pubmed ID: 20380418 Regionsspezifische Protein Fülle Veränderungen Im Gehirn Von MPTP-induzierter Morbus Parkinson-Maus-Modell Journal of Proteome Research. Mar, 2010 | Pubmed ID: 20155936 Endogene 3,4-Tyrosinhydroxylase Und Dopaquinone Modifikationen Auf Protein-Tyrosin: Links Zu Mitochondrially Abgeleiteten Oxidativer Stress Durch Hydroxyl-radikale Molecular & Cellular Proteomics : MCP. Jun, 2010 | Pubmed ID: 20124354 Mapping Protein Abundance Patterns in the Brain Using Voxelation Combined with Liquid Chromatography and Mass Spectrometry Methods (San Diego, Calif.). Feb, 2010 | Pubmed ID: 19654045 N-terminal Enrichment: Developing a Protocol to Detect Specific Proteolytic Fragments Journal of Biomolecular Techniques : JBT. Dec, 2009 | Pubmed ID: 19949699 Mouse-specific Tandem IgY7-SuperMix Immunoaffinity Separations for Improved LC-MS/MS Coverage of the Plasma Proteome Journal of Proteome Research. Nov, 2009 | Pubmed ID: 19722698 A Statistical Framework for Protein Quantitation in Bottom-up MS-based Proteomics Bioinformatics (Oxford, England). Aug, 2009 | Pubmed ID: 19535538 An Extensive Survey of Tyrosine Phosphorylation Revealing New Sites in Human Mammary Epithelial Cells Journal of Proteome Research. Aug, 2009 | Pubmed ID: 19534553 Dual Spatial Maps of Transcript and Protein Abundance in the Mouse Brain Expert Review of Proteomics. Jun, 2009 | Pubmed ID: 19489697 A Simple Procedure for Effective Quenching of Trypsin Activity and Prevention of 18O-labeling Back-exchange Journal of Proteome Research. May, 2009 | Pubmed ID: 19222237 Large-scale Multiplexed Quantitative Discovery Proteomics Enabled by the Use of an (18)O-labeled "universal" Reference Sample Journal of Proteome Research. Jan, 2009 | Pubmed ID: 19053531 Quantitative Phosphoproteome Analysis of Lysophosphatidic Acid Induced Chemotaxis Applying Dual-step (18)O Labeling Coupled with Immobilized Metal-ion Affinity Chromatography Journal of Proteome Research. Oct, 2008 | Pubmed ID: 18785766 Enhanced Detection of Low Abundance Human Plasma Proteins Using a Tandem IgY12-SuperMix Immunoaffinity Separation Strategy Molecular & Cellular Proteomics : MCP. Oct, 2008 | Pubmed ID: 18632595 Characterization of the Mouse Pancreatic Islet Proteome and Comparative Analysis with Other Mouse Tissues Journal of Proteome Research. Aug, 2008 | Pubmed ID: 18570455 DAnTE: a Statistical Tool for Quantitative Analysis of -omics Data Bioinformatics (Oxford, England). Jul, 2008 | Pubmed ID: 18453552 Quantitative Proteome Zuordnung Von Nitrotyrosines Methods in Enzymology. 2008 | Pubmed ID: 18423218 Proteome-wide Identification of Proteins and Their Modifications with Decreased Ambiguities and Improved False Discovery Rates Using Unique Sequence Tags Analytical Chemistry. Mar, 2008 | Pubmed ID: 18271604 Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis Revealed by Proteomic and Transcriptomic Analyses of the Striata in Two Mouse Models of Parkinson's Disease Journal of Proteome Research. Feb, 2008 | Pubmed ID: 18173235 Elimination of Systematic Mass Measurement Errors in Liquid Chromatography-mass Spectrometry Based Proteomics Using Regression Models and a Priori Partial Knowledge of the Sample Content Analytical Chemistry. Feb, 2008 | Pubmed ID: 18163597 Application of Proteomics in the Discovery of Candidate Protein Biomarkers in a Diabetes Autoantibody Standardization Program Sample Subset Journal of Proteome Research. Feb, 2008 | Pubmed ID: 18092746 Capillary-based Multi Nanoelectrospray Emitters: Improvements in Ion Transmission Efficiency and Implementation with Capillary Reversed-phase LC-ESI-MS Analytical Chemistry. Jan, 2008 | Pubmed ID: 18044958 Accurate Mass Measurements in Proteomics Chemical Reviews. Aug, 2007 | Pubmed ID: 17649984 A Genome-scale Map of Expression for a Mouse Brain Section Obtained Using Voxelation Physiological Genomics. Aug, 2007 | Pubmed ID: 17504947 A Method for Selective Enrichment and Analysis of Nitrotyrosine-containing Peptides in Complex Proteome Samples Journal of Proteome Research. Jun, 2007 | Pubmed ID: 17497906 Profiling Signaling Polarity in Chemotactic Cells Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17494752 Quantitative Analysis of Human Immunodeficiency Virus Type 1-infected CD4+ Cell Proteome: Dysregulated Cell Cycle Progression and Nuclear Transport Coincide with Robust Virus Production Journal of Virology. Jul, 2007 | Pubmed ID: 17494070 The Use of a Quantitative Cysteinyl-peptide Enrichment Technology for High-throughput Quantitative Proteomics Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 17484113 Quantitative Proteomic Approaches for Studying Phosphotyrosine Signaling Expert Review of Proteomics. Feb, 2007 | Pubmed ID: 17288512 Spatial Mapping of Protein Abundances in the Mouse Brain by Voxelation Integrated with High-throughput Liquid Chromatography-mass Spectrometry Genome Research. Mar, 2007 | Pubmed ID: 17255552 Characterization of the Human Pancreatic Islet Proteome by Two-dimensional LC/MS/MS Journal of Proteome Research. Dec, 2006 | Pubmed ID: 17137336 Advances and Challenges in Liquid Chromatography-mass Spectrometry-based Proteomics Profiling for Clinical Applications Molecular & Cellular Proteomics : MCP. Oct, 2006 | Pubmed ID: 16887931 Evaluation of Multiprotein Immunoaffinity Subtraction for Plasma Proteomics and Candidate Biomarker Discovery Using Mass Spectrometry Molecular & Cellular Proteomics : MCP. Nov, 2006 | Pubmed ID: 16854842 Endogenously Nitrated Proteins in Mouse Brain: Links to Neurodegenerative Disease Biochemistry. Jul, 2006 | Pubmed ID: 16800626 High Dynamic Range Characterization of the Trauma Patient Plasma Proteome Molecular & Cellular Proteomics : MCP. Oct, 2006 | Pubmed ID: 16684767 Characterization of the Mouse Brain Proteome Using Global Proteomic Analysis Complemented with Cysteinyl-peptide Enrichment Journal of Proteome Research. Feb, 2006 | Pubmed ID: 16457602 Normalization Approaches for Removing Systematic Biases Associated with Mass Spectrometry and Label-free Proteomics Journal of Proteome Research. Feb, 2006 | Pubmed ID: 16457593 Advances in Proteomics Data Analysis and Display Using an Accurate Mass and Time Tag Approach Mass Spectrometry Reviews. May-Jun, 2006 | Pubmed ID: 16429408 Development and Evaluation of a Micro- and Nanoscale Proteomic Sample Preparation Method Journal of Proteome Research. Nov-Dec, 2005 | Pubmed ID: 16335993 Human Plasma N-glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry Journal of Proteome Research. Nov-Dec, 2005 | Pubmed ID: 16335952 Utilizing Human Blood Plasma for Proteomic Biomarker Discovery Journal of Proteome Research. Jul-Aug, 2005 | Pubmed ID: 16083256 Quantitative Proteome Analysis of Human Plasma Following in Vivo Lipopolysaccharide Administration Using 16O/18O Labeling and the Accurate Mass and Time Tag Approach Molecular & Cellular Proteomics : MCP. May, 2005 | Pubmed ID: 15753121 Improved Proteome Coverage by Using High Efficiency Cysteinyl Peptide Enrichment: the Human Mammary Epithelial Cell Proteome Proteomics. Apr, 2005 | Pubmed ID: 15742320 Probability-based Evaluation of Peptide and Protein Identifications from Tandem Mass Spectrometry and SEQUEST Analysis: the Human Proteome Journal of Proteome Research. Jan-Feb, 2005 | Pubmed ID: 15707357 Targeted Comparative Proteomics by Liquid Chromatography-tandem Fourier Ion Cyclotron Resonance Mass Spectrometry Analytical Chemistry. Jan, 2005 | Pubmed ID: 15649034 Comparative Proteome Analyses of Human Plasma Following in Vivo Lipopolysaccharide Administration Using Multidimensional Separations Coupled with Tandem Mass Spectrometry Proteomics. Feb, 2005 | Pubmed ID: 15627965 High-throughput Proteomics Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Expert Review of Proteomics. Jun, 2004 | Pubmed ID: 15966802 Simultaneous Monitoring of Zn2+ Secretion and Intracellular Ca2+ from Islets and Islet Cells by Fluorescence Microscopy BioTechniques. Dec, 2004 | Pubmed ID: 15597541 High-throughput Comparative Proteome Analysis Using a Quantitative Cysteinyl-peptide Enrichment Technology Analytical Chemistry. Sep, 2004 | Pubmed ID: 15362891 Phosphoprotein Isotope-coded Solid-phase Tag Approach for Enrichment and Quantitative Analysis of Phosphopeptides from Complex Mixtures Analytical Chemistry. Oct, 2003 | Pubmed ID: 14714534 Late-life Restoration of Mitochondrial Function Reverses Cardiac Dysfunction in Old Mice ELife. | Pubmed ID: 32648542 Harzgestützte Erfassung in Verbindung mit isobarer Tandem-Massenmarkierung für eine multiplexige Quantifizierung der Proteinthioloxidation Matthew J. Gaffrey1, Nicholas J. Day1, Xiaolu Li2, Wei-Jun Qian1 1Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, 2Bioproducts Sciences and Engineering Laboratory, Department of Biological Systems Engineering, Washington State University JoVE 62671 Biochemistry Carrier-assisted One-pot Sample Preparation for Targeted Proteomics Analysis of Small Numbers of Human Cells JoVE 61797 Biochemistry
Harzgestützte Erfassung in Verbindung mit isobarer Tandem-Massenmarkierung für eine multiplexige Quantifizierung der Proteinthioloxidation Matthew J. Gaffrey1, Nicholas J. Day1, Xiaolu Li2, Wei-Jun Qian1 1Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, 2Bioproducts Sciences and Engineering Laboratory, Department of Biological Systems Engineering, Washington State University JoVE 62671 Biochemistry
Carrier-assisted One-pot Sample Preparation for Targeted Proteomics Analysis of Small Numbers of Human Cells JoVE 61797 Biochemistry