Wei Kong

Publications

• Nidogen-2 is a Novel Endogenous Ligand of LGR4 to Inhibit Vascular Calcification
  Circulation Research. Nov, 2022  |   Pubmed ID: 36354004
• PHB2 Maintains the Contractile Phenotype of VSMCs by Counteracting PKM2 Splicing
  Circulation Research. Oct, 2022  |   Pubmed ID: 36200440
• MicroRNA-Disease Network Analysis Repurposes Methotrexate for the Treatment of Abdominal Aortic Aneurysm in Mice
  Genomics, Proteomics & Bioinformatics. Aug, 2022  |   Pubmed ID: 36030000
• Matricellular Proteins: Potential Biomarkers and Mechanistic Factors in Aortic Aneurysms
  Journal of Molecular and Cellular Cardiology. Aug, 2022  |   Pubmed ID: 35576729
• Endogenous Hydrogen Sulfide Persulfidates Caspase-3 at Cysteine 163 to Inhibit Doxorubicin-Induced Cardiomyocyte Apoptosis
  Oxidative Medicine and Cellular Longevity. 2022  |   Pubmed ID: 35571249
• Investigating the Inverse Association Between Glycaemia and Abdominal Aortic Dilatation in a Large Chinese Hypertensive Population: a Cross-sectional Study
  Annals of Translational Medicine. Apr, 2022  |   Pubmed ID: 35530958
• Targeting Macrophage TFEB-14-3-3 Epsilon Interface by Naringenin Inhibits Abdominal Aortic Aneurysm
  Cell Discovery. Mar, 2022  |   Pubmed ID: 35228523
• Single-cell RNA Sequencing Reveals B Cell-T Cell Interactions in Vascular Adventitia of Hyperhomocysteinemia-accelerated Atherosclerosis
  Protein & Cell. 07, 2022  |   Pubmed ID: 35175542
• Vascular Smooth Muscle Cell-derived Hydrogen Sulfide Promotes Atherosclerotic Plaque Stability Via TFEB (transcription Factor EB)-mediated Autophagy
  Autophagy. 10, 2022  |   Pubmed ID: 35090378
• COMP (Cartilage Oligomeric Matrix Protein), a Novel PIEZO1 Regulator That Controls Blood Pressure
  Hypertension (Dallas, Tex. : 1979). 03, 2022  |   Pubmed ID: 34983194
• The Binding of Autotaxin to Integrins Mediates Hyperhomocysteinemia-potentiated Platelet Activation and Thrombosis in Mice and Humans
  Blood Advances. 01, 2022  |   Pubmed ID: 34559203
• Association Between Lipid Levels and Risk for Different Types of Aneurysms: A Mendelian Randomization Study
  Journal of Personalized Medicine. Nov, 2021  |   Pubmed ID: 34834523
• Pan-HDAC (Histone Deacetylase) Inhibitors Increase Susceptibility of Thoracic Aortic Aneurysm and Dissection in Mice
  Arteriosclerosis, Thrombosis, and Vascular Biology. 11, 2021  |   Pubmed ID: 34525846
• Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation Via Bridging Jagged1-Notch3 Signaling
  Circulation. 10, 2021  |   Pubmed ID: 34315224
• Whole-Mount Kidney Clearing and Visualization Reveal Renal Sympathetic Hyperinnervation in Heart Failure Mice
  Frontiers in Physiology. 2021  |   Pubmed ID: 34305650
• Identification of COL3A1 Variants Associated with Sporadic Thoracic Aortic Dissection: a Case-control Study
  Frontiers of Medicine. Jun, 2021  |   Pubmed ID: 34047934
• Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension
  Circulation Research. 07, 2021  |   Pubmed ID: 33980031
• LOXL4 Abrogation Does Not Exaggerate Angiotensin II-Induced Thoracic or Abdominal Aortic Aneurysm in Mice
  Genes. 03, 2021  |   Pubmed ID: 33807332
• X-box Binding Protein 1-mediated COL4A1s Secretion Regulates Communication Between Vascular Smooth Muscle and Stem/progenitor Cells
  The Journal of Biological Chemistry. Jan-Jun, 2021  |   Pubmed ID: 33722606
• Endogenous SO-dependent Smad3 Redox Modification Controls Vascular Remodeling
  Redox Biology. 05, 2021  |   Pubmed ID: 33647858
• Cartilage Oligomeric Matrix Protein is an Endogenous β-arrestin-2-selective Allosteric Modulator of AT1 Receptor Counteracting Vascular Injury
  Cell Research. 07, 2021  |   Pubmed ID: 33510386
• Cartilage Oligomeric Matrix Protein Fine-tunes Disturbed Flow-induced Endothelial Activation and Atherogenesis
  Matrix Biology : Journal of the International Society for Matrix Biology. 01, 2021  |   Pubmed ID: 33068727
• NSun2 Regulates Aneurysm Formation by Promoting Autotaxin Expression and T Cell Recruitment
  Cellular and Molecular Life Sciences : CMLS. Feb, 2021  |   Pubmed ID: 32734582
• Vascular Extracellular Matrix Remodeling and Hypertension
  Antioxidants & Redox Signaling. 04, 2021  |   Pubmed ID: 32460598
• Post-translational Modifications of IκBα: The State of the Art
  Frontiers in Cell and Developmental Biology. 2020  |   Pubmed ID: 33224945
• FAM3D is Essential for Colon Homeostasis and Host Defense Against Inflammation Associated Carcinogenesis
  Nature Communications. 11, 2020  |   Pubmed ID: 33219235
• Naringin Alleviates Atherosclerosis in ApoE Mice by Regulating Cholesterol Metabolism Involved in Gut Microbiota Remodeling
  Journal of Agricultural and Food Chemistry. Nov, 2020  |   Pubmed ID: 33107729
• DeSiphering Receptor Core-induced and Ligand-dependent Conformational Changes in Arrestin Via Genetic Encoded Trimethylsilyl H-NMR Probe
  Nature Communications. 09, 2020  |   Pubmed ID: 32978402
• Extracellular Matrix Dynamics in Vascular Remodeling
  American Journal of Physiology. Cell Physiology. 09, 2020  |   Pubmed ID: 32579472
• Kindlin-2 Deficiency Induces Fatal Intestinal Obstruction in Mice
  Theranostics. 2020  |   Pubmed ID: 32483447
• Elevated Serum Cartilage Oligomeric Matrix Protein and the Metalloproteinase-ADAMTS7 Levels Are Associated with Vascular Calcification in Maintenance Hemodialysis Patients
  Seminars in Dialysis. 07, 2020  |   Pubmed ID: 32441044
• Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm
  Arteriosclerosis, Thrombosis, and Vascular Biology. 05, 2020  |   Pubmed ID: 32212850
• Cellular Signaling in Abdominal Aortic Aneurysm
  Cellular Signalling. 06, 2020  |   Pubmed ID: 32088371
• Macrophage-derived Sulfur Dioxide is a Novel Inflammation Regulator
  Biochemical and Biophysical Research Communications. 04, 2020  |   Pubmed ID: 32057367
• Hypermethylation of Mitochondrial DNA in Vascular Smooth Muscle Cells Impairs Cell Contractility
  Cell Death & Disease. 01, 2020  |   Pubmed ID: 31959742
• PSMP/MSMP Promotes Hepatic Fibrosis Through CCR2 and Represents a Novel Therapeutic Target
  Journal of Hepatology. 03, 2020  |   Pubmed ID: 31813573
• B Cell-derived Anti-beta 2 Glycoprotein I Antibody Contributes to Hyperhomocysteinaemia-aggravated Abdominal Aortic Aneurysm
  Cardiovascular Research. 09, 2020  |   Pubmed ID: 31782769
• Endothelial Tight Junctions and Their Regulatory Signaling Pathways in Vascular Homeostasis and Disease
  Cellular Signalling. 02, 2020  |   Pubmed ID: 31770579
• L-Cystathionine Protects Against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells
  Oxidative Medicine and Cellular Longevity. 2019  |   Pubmed ID: 31885769
• Kindlin-2 Suppresses Transcription Factor GATA4 Through Interaction with SUV39H1 to Attenuate Hypertrophy
  Cell Death & Disease. 11, 2019  |   Pubmed ID: 31767831
• Genetically Encoded Fluorescent Amino Acid for Monitoring Protein Interactions Through FRET
  Analytical Chemistry. 12, 2019  |   Pubmed ID: 31670502
• Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism
  Cell Metabolism. 11, 2019  |   Pubmed ID: 31668872
• Endogenous Hydrogen Sulfide Sulfhydrates IKKβ at Cysteine 179 to Control Pulmonary Artery Endothelial Cell Inflammation
  Clinical Science (London, England : 1979). 10, 2019  |   Pubmed ID: 31654061
• Macrophage Metabolic Reprogramming Aggravates Aortic Dissection Through the HIF1α-ADAM17 Pathway
  EBioMedicine. Nov, 2019  |   Pubmed ID: 31640947
• Ablation of Gut Microbiota Alleviates Obesity-induced Hepatic Steatosis and Glucose Intolerance by Modulating Bile Acid Metabolism in Hamsters
  Acta Pharmaceutica Sinica. B. Jul, 2019  |   Pubmed ID: 31384531
• The -methyladenosine (mA)-forming Enzyme METTL3 Facilitates M1 Macrophage Polarization Through the Methylation of MRNA
  American Journal of Physiology. Cell Physiology. 10, 2019  |   Pubmed ID: 31365297
• Rapamycin Attenuates a Murine Model of Thoracic Aortic Aneurysm by Downregulating the MiR-126-3p Mediated Activation of MAPK/ERK Signalling Pathway
  Biochemical and Biophysical Research Communications. 05, 2019  |   Pubmed ID: 30904162
• Gpihbp1 Deficiency Accelerates Atherosclerosis and Plaque Instability in Diabetic Ldlr Mice
  Atherosclerosis. 03, 2019  |   Pubmed ID: 30721842
• DNA Methyltransferase 1 and Krüppel-like Factor 4 Axis Regulates Macrophage Inflammation and Atherosclerosis
  Journal of Molecular and Cellular Cardiology. 03, 2019  |   Pubmed ID: 30659837
• Rapamycin Prevents Thoracic Aortic Aneurysm and Dissection in Mice
  Journal of Vascular Surgery. 03, 2019  |   Pubmed ID: 30253896
• Postnatal Deficiency of ADAMTS1 Ameliorates Thoracic Aortic Aneurysm and Dissection in Mice
  Experimental Physiology. 12, 2018  |   Pubmed ID: 30191627
• Naringenin Inhibits N-nitro-L-arginine Methyl Ester-induced Hypertensive Left Ventricular Hypertrophy by Decreasing Angiotensin-converting Enzyme 1 Expression
  Experimental and Therapeutic Medicine. Aug, 2018  |   Pubmed ID: 30112041
• Cartilage Oligomeric Matrix Protein is a Novel Notch Ligand Driving Embryonic Stem Cell Differentiation Towards the Smooth Muscle Lineage
  Journal of Molecular and Cellular Cardiology. 08, 2018  |   Pubmed ID: 29981303
• Histone Variant H2A.Z Is Required for the Maintenance of Smooth Muscle Cell Identity As Revealed by Single-Cell Transcriptomics
  Circulation. 11, 2018  |   Pubmed ID: 29871976
• COMP-prohibitin 2 Interaction Maintains Mitochondrial Homeostasis and Controls Smooth Muscle Cell Identity
  Cell Death & Disease. 06, 2018  |   Pubmed ID: 29867124
• Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development
  Arteriosclerosis, Thrombosis, and Vascular Biology. 07, 2018  |   Pubmed ID: 29853563
• The Increased Endogenous Sulfur Dioxide Acts As a Compensatory Mechanism for the Downregulated Endogenous Hydrogen Sulfide Pathway in the Endothelial Cell Inflammation
  Frontiers in Immunology. 2018  |   Pubmed ID: 29760703
• Renal Injury in Seipin-deficient Lipodystrophic Mice and Its Reversal by Adipose Tissue Transplantation or Leptin Administration Alone: Adipose Tissue-kidney Crosstalk
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 10, 2018  |   Pubmed ID: 29738274
• Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance
  EBioMedicine. May, 2018  |   Pubmed ID: 29735414
• Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2
  Circulation. 07, 2018  |   Pubmed ID: 29453251
• Gq Activity- and β-arrestin-1 Scaffolding-mediated ADGRG2/CFTR Coupling Are Required for Male Fertility
  ELife. 02, 2018  |   Pubmed ID: 29393851
• Extracellular Matrix Remodeling and Cardiac Fibrosis
  Matrix Biology : Journal of the International Society for Matrix Biology. 08, 2018  |   Pubmed ID: 29371055
• Homocysteine Directly Interacts and Activates the Angiotensin II Type I Receptor to Aggravate Vascular Injury
  Nature Communications. 01, 2018  |   Pubmed ID: 29296021
• Matrix Stiffness Determines the Phenotype of Vascular Smooth Muscle Cell In vitro and In vivo: Role of DNA Methyltransferase 1
  Biomaterials. Feb, 2018  |   Pubmed ID: 29182961
• Small Infrarenal Aortic Diameter Associated with Lower-extremity Peripheral Artery Disease in Chinese Hypertensive Adults
  Scientific Reports. 11, 2017  |   Pubmed ID: 29109408
• Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation Via FoxO4 Interaction
  Circulation Research. Dec, 2017  |   Pubmed ID: 29089350
• Hypoxia Decrease Expression of Cartilage Oligomeric Matrix Protein to Promote Phenotype Switching of Pulmonary Arterial Smooth Muscle Cells
  The International Journal of Biochemistry & Cell Biology. 10, 2017  |   Pubmed ID: 28860005
• Hyperhomocysteinemia and Vascular Injury: The Advance of Mechanisms and Drug Targets
  British Journal of Pharmacology. Aug, 2017  |   Pubmed ID: 28836260
• Basic and Translational Vascular Research in China: Past, Present, and Future
  Circulation Research. 08, 2017  |   Pubmed ID: 28775012
• CYLD Deubiquitinates Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Contributing to Adventitial Remodeling
  Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2017  |   Pubmed ID: 28751569
• Transdifferentiated Human Vascular Smooth Muscle Cells Are a New Potential Cell Source for Endothelial Regeneration
  Scientific Reports. 07, 2017  |   Pubmed ID: 28717251
• Cardioprotection of Ischemic Preconditioning in Rats Involves Upregulating Adiponectin
  Journal of Molecular Endocrinology. 05, 2017  |   Pubmed ID: 28219936
• Cartilage Oligomeric Matrix Protein: Matricellular and Matricrine Signaling in Cardiovascular Homeostasis and Disease
  Current Vascular Pharmacology. 2017  |   Pubmed ID: 28155614
• ADAM17: A Molecular Switch to Control TNFR2 During Atherogenesis In Vivo
  Arteriosclerosis, Thrombosis, and Vascular Biology. 02, 2017  |   Pubmed ID: 28122773
• [The Mechanisms of Medial Vascular Calcification]
  Sheng Li Xue Bao : [Acta Physiologica Sinica]. Oct, 2016  |   Pubmed ID: 27778024
• The E3 Ubiquitin Ligase C-Cbl Mediates Integrin β1 Ubiquitination During Dilated Cardiomyopathy
  Biochemical and Biophysical Research Communications. Oct, 2016  |   Pubmed ID: 27693578
• Cartilage Oligomeric Matrix Protein Prevents Vascular Aging and Vascular Smooth Muscle Cells Senescence
  Biochemical and Biophysical Research Communications. Sep, 2016  |   Pubmed ID: 27498005
• ECM-mimetic Heparin Glycosamioglycan-functionalized Surface Favors Constructing Functional Vascular Smooth Muscle Tissue in Vitro
  Colloids and Surfaces. B, Biointerfaces. Oct, 2016  |   Pubmed ID: 27351139
• Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification
  Circulation Research. Jul, 2016  |   Pubmed ID: 27151399
• Hyaluronan Is Crucial for Stem Cell Differentiation into Smooth Muscle Lineage
  Stem Cells (Dayton, Ohio). 05, 2016  |   Pubmed ID: 26867148
• A Disintegrin and Metalloproteinase with Thrombospondin Motif 1 (ADAMTS1) Expression Increases in Acute Aortic Dissection
  Science China. Life Sciences. Jan, 2016  |   Pubmed ID: 26563155
• Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2016  |   Pubmed ID: 26543101
• Predicting Abdominal Aortic Aneurysm Target Genes by Level-2 Protein-Protein Interaction
  PloS One. 2015  |   Pubmed ID: 26496478
• Mammalian Target of Rapamycin Signaling Inhibition Ameliorates Vascular Calcification Via Klotho Upregulation
  Kidney International. Oct, 2015  |   Pubmed ID: 26061549
• Cartilage Oligomeric Matrix Protein is a Natural Inhibitor of Thrombin
  Blood. Aug, 2015  |   Pubmed ID: 26045608
• ADAMTS-7 Promotes Vascular Smooth Muscle Cells Proliferation in Vitro and in Vivo
  Science China. Life Sciences. Jul, 2015  |   Pubmed ID: 25921940
• ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1
  Circulation. Feb, 2015  |   Pubmed ID: 25712208
• Macrophage Inflammasome Mediates Hyperhomocysteinemia-aggravated Abdominal Aortic Aneurysm
  Journal of Molecular and Cellular Cardiology. Apr, 2015  |   Pubmed ID: 25680906
• Disruption of TGF-β Signaling in Smooth Muscle Cell Prevents Flow-induced Vascular Remodeling
  Biochemical and Biophysical Research Communications. Nov, 2014  |   Pubmed ID: 25451249
• Disruption of TGF-β Signaling in Smooth Muscle Cell Prevents Elastase-induced Abdominal Aortic Aneurysm
  Biochemical and Biophysical Research Communications. Nov, 2014  |   Pubmed ID: 25450370
• Hyperhomocysteinemia and Methylenetetrahydrofolate Reductase Polymorphism in Cervical Artery Dissection: a Meta-analysis
  Cerebrovascular Diseases (Basel, Switzerland). 2014  |   Pubmed ID: 24903192
• Intermedin Inhibits Macrophage Foam-cell Formation Via Tristetraprolin-mediated Decay of CD36 MRNA
  Cardiovascular Research. Feb, 2014  |   Pubmed ID: 24253523
• Deficiency of Cartilage Oligomeric Matrix Protein Causes Dilated Cardiomyopathy
  Basic Research in Cardiology. Sep, 2013  |   Pubmed ID: 23917519
• Hyperhomocysteinemia Promotes Insulin Resistance by Inducing Endoplasmic Reticulum Stress in Adipose Tissue
  The Journal of Biological Chemistry. Apr, 2013  |   Pubmed ID: 23417716
• Phosphate-induced Autophagy Counteracts Vascular Calcification by Reducing Matrix Vesicle Release
  Kidney International. Jun, 2013  |   Pubmed ID: 23364520
• CTLA4-IgG Ameliorates Homocysteine-accelerated Atherosclerosis by Inhibiting T-cell Overactivation in ApoE(-/-) Mice
  Cardiovascular Research. Feb, 2013  |   Pubmed ID: 23118130
• Upregulation of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-7 by MiR-29 Repression Mediates Vascular Smooth Muscle Calcification
  Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2012  |   Pubmed ID: 22995515
• Hyperhomocysteinemia Exaggerates Adventitial Inflammation and Angiotensin II-induced Abdominal Aortic Aneurysm in Mice
  Circulation Research. Oct, 2012  |   Pubmed ID: 22912384
• Fenofibrate Inhibited the Differentiation of T Helper 17 Cells in Vitro
  PPAR Research. 2012  |   Pubmed ID: 22792085
• Fenofibrate Enhances the in Vitro Differentiation of Foxp3(+) Regulatory T Cells in Mice
  PPAR Research. 2012  |   Pubmed ID: 22536210
• Activation of Nuclear Factor-kappa B Accelerates Vascular Calcification by Inhibiting Ankylosis Protein Homolog Expression
  Kidney International. Jul, 2012  |   Pubmed ID: 22437419
• Small-molecule Inhibition of Human Immunodeficiency Virus Type 1 Replication by Targeting the Interaction Between Vif and ElonginC
  Journal of Virology. May, 2012  |   Pubmed ID: 22379088
• Homocysteine Upregulates Soluble Epoxide Hydrolase in Vascular Endothelium in Vitro and in Vivo
  Circulation Research. Mar, 2012  |   Pubmed ID: 22354938
• Mitochondrial Reactive Oxygen Species Promote P65 Nuclear Translocation Mediating High-phosphate-induced Vascular Calcification in Vitro and in Vivo
  Kidney International. May, 2011  |   Pubmed ID: 21368742
• Cartilage Oligomeric Matrix Protein Inhibits Vascular Smooth Muscle Calcification by Interacting with Bone Morphogenetic Protein-2
  Circulation Research. Apr, 2011  |   Pubmed ID: 21350216
• A Novel Mechanism of γ/δ T-lymphocyte and Endothelial Activation by Shear Stress: the Role of Ecto-ATP Synthase β Chain
  Circulation Research. Feb, 2011  |   Pubmed ID: 21193741
• [Diabetic Cardiomyopathy]
  Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. Feb, 2010  |   Pubmed ID: 21417012
• [The Role of Adventitia in Atherosclerosis]
  Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. Jun, 2010  |   Pubmed ID: 21416976
• Cartilage Oligomeric Matrix Protein Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells by Interacting with Alpha(7)beta(1) Integrin
  Circulation Research. Feb, 2010  |   Pubmed ID: 20019333
• Homocysteine Promotes Vascular Smooth Muscle Cell Migration by Induction of the Adipokine Resistin
  American Journal of Physiology. Cell Physiology. Dec, 2009  |   Pubmed ID: 19828833
• Regulatory T Cells Ameliorate Hyperhomocysteinaemia-accelerated Atherosclerosis in ApoE-/- Mice
  Cardiovascular Research. Oct, 2009  |   Pubmed ID: 19502284
• ADAMTS-7 Mediates Vascular Smooth Muscle Cell Migration and Neointima Formation in Balloon-injured Rat Arteries
  Circulation Research. Mar, 2009  |   Pubmed ID: 19168437
• Regulatory Role of Thioredoxin in Homocysteine-induced Monocyte Chemoattractant Protein-1 Secretion in Monocytes/macrophages
  FEBS Letters. Nov, 2008  |   Pubmed ID: 18976655
• [Extracellular Matrix, Matrix-degrading Proteases and Vascular Calcification]
  Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. Jul, 2008  |   Pubmed ID: 18819486