Wen-Quan Zou Department of Pathology, National Prion Disease Pathology Surveillance Center Case Western Reserve University School of Medicine Biography Publications Institution JoVE Articles Wen-Quan Zou has not added a biography. If you are Wen-Quan Zou and would like to personalize this page please email our Author Liaison for assistance. Publications Sporadic Fatal Insomnia with Clinical, Laboratory, and Genetic Findings Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Aug, 2012 | Pubmed ID: 22717776 Creutzfeldt-Jakob Disease with Unusually Extensive Neuropathology in a Child Treated with Native Human Growth Hormone Clinical Neuropathology. May-Jun, 2012 | Pubmed ID: 22551916 Cellular Prion Protein is Essential for Oligomeric Amyloid-β-induced Neuronal Cell Death Human Molecular Genetics. Mar, 2012 | Pubmed ID: 22100763 Alkylating Antitumor Drug Mechlorethamine Conceals a Structured PrP Domain and Inhibits in Vitro Prion Amplification Journal of Toxicology and Environmental Health. Part A. 2011 | Pubmed ID: 22043910 Sporadic Fatal Insomnia in a Young Woman: a Diagnostic Challenge: Case Report BMC Neurology. 2011 | Pubmed ID: 22040318 Characterization of Spontaneously Generated Prion-like Conformers in Cultured Cells Aging. Oct, 2011 | Pubmed ID: 21990137 Pulling Rabbits to Reveal the Secrets of the Prion Protein Communicative & Integrative Biology. May, 2011 | Pubmed ID: 21980555 Insoluble Cellular Prion Protein and Its Association with Prion and Alzheimer Diseases Prion. Jul-Sep, 2011 | Pubmed ID: 21847014 Variably Protease-sensitive Prionopathy: a Novel Disease of the Prion Protein Journal of Molecular Neuroscience : MN. Nov, 2011 | Pubmed ID: 21584652 Amyloid-beta42 Interacts Mainly with Insoluble Prion Protein in the Alzheimer Brain The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21393248 Molecular Biology and Pathology of Prion Strains in Sporadic Human Prion Diseases Acta Neuropathologica. Jan, 2011 | Pubmed ID: 21058033 Agent Strain Variation in Human Prion Disease: Insights from a Molecular and Pathological Review of the National Institutes of Health Series of Experimentally Transmitted Disease Brain : a Journal of Neurology. Oct, 2010 | Pubmed ID: 20823086 Sequence-dependent Prion Protein Misfolding and Neurotoxicity The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20817727 Variably Protease-sensitive Prionopathy: a New Sporadic Disease of the Prion Protein Annals of Neurology. Aug, 2010 | Pubmed ID: 20695009 PrP Conformational Transitions Alter Species Preference of a PrP-specific Antibody The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20194495 Multiorgan Detection and Characterization of Protease-resistant Prion Protein in a Case of Variant CJD Examined in the United States PloS One. 2010 | Pubmed ID: 20098730 Co-existence of Scrapie Prion Protein Types 1 and 2 in Sporadic Creutzfeldt-Jakob Disease: Its Effect on the Phenotype and Prion-type Characteristics Brain : a Journal of Neurology. Oct, 2009 | Pubmed ID: 19734292 Failure to Detect the Presence of Prions in the Uterine and Gestational Tissues from a Gravida with Creutzfeldt-Jakob Disease The American Journal of Pathology. May, 2009 | Pubmed ID: 19349373 Variant Creutzfeldt-Jakob Disease: French Versus British Annals of Neurology. Mar, 2009 | Pubmed ID: 19334065 Characterization of Truncated Forms of Abnormal Prion Protein in Creutzfeldt-Jakob Disease The Journal of Biological Chemistry. Nov, 2008 | Pubmed ID: 18753138 Creutzfeldt-Jakob Disease in Recipients of Corneal Transplants Cornea. Aug, 2008 | Pubmed ID: 18650677 Sporadic Fatal Insomnia Masquerading As a Paraneoplastic Cerebellar Syndrome Archives of Neurology. Jul, 2008 | Pubmed ID: 18625868 A Novel Human Disease with Abnormal Prion Protein Sensitive to Protease Annals of Neurology. Jun, 2008 | Pubmed ID: 18571782 Evaluation of the Human Transmission Risk of an Atypical Bovine Spongiform Encephalopathy Prion Strain Journal of Virology. Apr, 2008 | Pubmed ID: 18234793 Toxic Effects of Intracerebral PrP Antibody Administration During the Course of BSE Infection in Mice Prion. Jul-Sep, 2007 | Pubmed ID: 19164902 Insoluble Aggregates and Protease-resistant Conformers of Prion Protein in Uninfected Human Brains The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 16987816 Classification of Sporadic Creutzfeldt-Jakob Disease Revisited Brain : a Journal of Neurology. Sep, 2006 | Pubmed ID: 16923954 A Prion Disease--possible Gerstmann-Straussler-Scheinker Disease: a Case Report Journal of Computer Assisted Tomography. Jan-Feb, 2006 | Pubmed ID: 16365589 Creutzfeldt-Jakob Disease (CJD) with a Mutation at Codon 148 of Prion Protein Gene: Relationship with Sporadic CJD The American Journal of Pathology. Dec, 2005 | Pubmed ID: 16314483 Variant Creutzfeldt-Jakob Disease Death, United States Emerging Infectious Diseases. Sep, 2005 | Pubmed ID: 16229761 From Microbes to Prions the Final Proof of the Prion Hypothesis Cell. Apr, 2005 | Pubmed ID: 15851020 Concealment of Epitope by Reduction and Alkylation in Prion Protein Biochemical and Biophysical Research Communications. Jan, 2005 | Pubmed ID: 15596149 Protease-resistant Human Prion Protein and Ferritin Are Cotransported Across Caco-2 Epithelial Cells: Implications for Species Barrier in Prion Uptake from the Intestine The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2004 | Pubmed ID: 15601934 Antibody to DNA Detects Scrapie but Not Normal Prion Protein Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14734804 Identification of Novel Proteinase K-resistant C-terminal Fragments of PrP in Creutzfeldt-Jakob Disease The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917418 A Prion Protein Epitope Selective for the Pathologically Misfolded Conformation Nature Medicine. Jul, 2003 | Pubmed ID: 12778138 Acidic PH and Detergents Enhance in Vitro Conversion of Human Brain PrPC to a PrPSc-like Form The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12161431 Isolering af opløselige og uopløselige PrP Oligomerer i normal human hjerne Xiangzhu Xiao1, Jue Yuan1, Wen-Quan Zou1,2 1Department of Pathology, National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, 2Department of Neurology, National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine JoVE 3788 Medicine
Isolering af opløselige og uopløselige PrP Oligomerer i normal human hjerne Xiangzhu Xiao1, Jue Yuan1, Wen-Quan Zou1,2 1Department of Pathology, National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine, 2Department of Neurology, National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine JoVE 3788 Medicine