Yana Zavros Biography Publications JoVE Articles Yana Zavros has not added a biography. If you are Yana Zavros and would like to personalize this page please email our Author Liaison for assistance. Publications Human Gastrointestinal Organoid Models for Studying Microbial Disease and Cancer Current Topics in Microbiology and Immunology. 2021 | Pubmed ID: 32889597 Generation and Use of Gastric Organoids for the Study of Helicobacter Pylori Pathogenesis Methods in Cell Biology. 2020 | Pubmed ID: 32586445 The Novel Role of As a Regulator of Cell Homeostasis and Disease of the Gastric Oxyntic Mucosa Cellular and Molecular Gastroenterology and Hepatology. 2018 | Pubmed ID: 29713667 Initiation and Maintenance of Gastric Cancer: A Focus on CD44 Variant Isoforms and Cancer Stem Cells Cellular and Molecular Gastroenterology and Hepatology. Jul, 2017 | Pubmed ID: 28560289 CD44 Variant Isoform 9 Emerges in Response to Injury and Contributes to the Regeneration of the Gastric Epithelium The Journal of Pathology. Aug, 2017 | Pubmed ID: 28497484 Hedgehog Signalling in Myeloid Cells Impacts on Body Weight, Adipose Tissue Inflammation and Glucose Metabolism Diabetologia. 05, 2017 | Pubmed ID: 28233033 The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach Cellular and Molecular Gastroenterology and Hepatology. Sep, 2016 | Pubmed ID: 27990460 Hedgehog Signaling in the Stomach Current Opinion in Pharmacology. 12, 2016 | Pubmed ID: 27750091 Spatial and Temporal Shifts in Bacterial Biogeography and Gland Occupation During the Development of a Chronic Infection MBio. 10, 2016 | Pubmed ID: 27729513 Oncogenic Transformation of Human-Derived Gastric Organoids Methods in Molecular Biology (Clifton, N.J.). Aug, 2016 | Pubmed ID: 27539460 Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27246019 Organoid Models of Human Gastrointestinal Development And Disease Gastroenterology. 05, 2016 | Pubmed ID: 26774180 Characterization of Stem/progenitor Cell Cycle Using Murine Circumvallate Papilla Taste Bud Organoid Scientific Reports. Nov, 2015 | Pubmed ID: 26597788 CD44 Plays a Functional Role in Helicobacter Pylori-induced Epithelial Cell Proliferation PLoS Pathogens. Feb, 2015 | Pubmed ID: 25658601 The Use of Murine-derived Fundic Organoids in Studies of Gastric Physiology The Journal of Physiology. Jan, 2015 | Pubmed ID: 25605613 Helicobacter Pylori-induced Sonic Hedgehog Expression is Regulated by NFκB Pathway Activation: the Use of a Novel in Vitro Model to Study Epithelial Response to Infection Helicobacter. Feb, 2015 | Pubmed ID: 25495001 Helicobacter Pylori Targets Cancer-associated Apical-junctional Constituents in Gastroids and Gastric Epithelial Cells Gut. May, 2015 | Pubmed ID: 25123931 Crosstalks Between Cytokines and Sonic Hedgehog in Helicobacter Pylori Infection: a Mathematical Model PloS One. 2014 | Pubmed ID: 25364910 Modelling Human Development and Disease in Pluripotent Stem-cell-derived Gastric Organoids Nature. Dec, 2014 | Pubmed ID: 25363776 Motility and Chemotaxis Mediate the Preferential Colonization of Gastric Injury Sites by Helicobacter Pylori PLoS Pathogens. Jul, 2014 | Pubmed ID: 25033386 Indian Hedgehog Mediates Gastrin-induced Proliferation in Stomach of Adult Mice Gastroenterology. Sep, 2014 | Pubmed ID: 24859162 Mesenchymal Stem Cells Induce Epithelial Proliferation Within the Inflamed Stomach American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2014 | Pubmed ID: 24789207 Gastritis Promotes an Activated Bone Marrow-derived Mesenchymal Stem Cell with a Phenotype Reminiscent of a Cancer-promoting Cell Digestive Diseases and Sciences. Mar, 2014 | Pubmed ID: 24202649 Establishment of Gastrointestinal Epithelial Organoids Current Protocols in Mouse Biology. Dec, 2013 | Pubmed ID: 25105065 The Acid-secreting Parietal Cell As an Endocrine Source of Sonic Hedgehog During Gastric Repair Endocrinology. Dec, 2013 | Pubmed ID: 24092639 Sonic Hedgehog Mediates the Proliferation and Recruitment of Transformed Mesenchymal Stem Cells to the Stomach PloS One. 2013 | Pubmed ID: 24069395 Sonic Hedgehog Contributes to Gastric Mucosal Restitution After Injury Laboratory Investigation; a Journal of Technical Methods and Pathology. Jan, 2013 | Pubmed ID: 23090636 Techniques for Following Labeled Cells in Vivo: Use of X/Y FISH, Techniques to Optimize Fluorescent Detection, and Beta-galactosidase Detection Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 23015508 Variants in Autophagy Genes Affect Susceptibility to Both Crohn's Disease and Helicobacter Pylori Infection Gastroenterology. May, 2012 | Pubmed ID: 22449582 The Role of Sonic Hedgehog As a Regulator of Gastric Function and Differentiation Vitamins and Hormones. 2012 | Pubmed ID: 22391317 Gastric Sonic Hedgehog Acts As a Macrophage Chemoattractant During the Immune Response to Helicobacter Pylori Gastroenterology. Jan, 2012 | Pubmed ID: 22285806 Role of Sonic Hedgehog Signaling During Progression from Inflammation to Cancer in the Stomach World Journal of Gastrointestinal Pathophysiology. Dec, 2011 | Pubmed ID: 22180844 Histamine 3 Receptor Activation Mediates Inhibition of Acid Secretion During Helicobacter-induced Gastritis World Journal of Gastrointestinal Pathophysiology. Dec, 2010 | Pubmed ID: 21607157 Hedgehog Signaling Regulates E-cadherin Expression for the Maintenance of the Actin Cytoskeleton and Tight Junctions American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2010 | Pubmed ID: 20847300 Intracellular Calcium Release and Protein Kinase C Activation Stimulate Sonic Hedgehog Gene Expression During Gastric Acid Secretion Gastroenterology. Dec, 2010 | Pubmed ID: 20816837 The Role of Sonic Hedgehog Reemergence During Gastric Cancer Digestive Diseases and Sciences. Jun, 2010 | Pubmed ID: 20437100 Volume Density, Distribution, and Ultrastructure of Secretory and Basolateral Membranes and Mitochondria Predict Parietal Cell Secretory (dys)function Journal of Biomedicine & Biotechnology. 2010 | Pubmed ID: 20339514 The Full-length Unprocessed Hedgehog Protein is an Active Signaling Molecule The Journal of Biological Chemistry. Jan, 2010 | Pubmed ID: 19920144 Loss of Parietal Cell Expression of Sonic Hedgehog Induces Hypergastrinemia and Hyperproliferation of Surface Mucous Cells Gastroenterology. Feb, 2010 | Pubmed ID: 19909751 Sonic Hedgehog is Associated with H+-K+-ATPase-containing Membranes in Gastric Parietal Cells and Secreted with Histamine Stimulation American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2008 | Pubmed ID: 18483183 The Adventures of Sonic Hedgehog in Development and Repair. IV. Sonic Hedgehog Processing, Secretion, and Function in the Stomach American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2008 | Pubmed ID: 18308861 A Preclinical Human-Derived Autologous Gastric Cancer Organoid/Immune Cell Co-Culture Model to Predict the Efficacy of Targeted Therapies JoVE 61443 Medicine الفأر والإنسان-المستمدة من الثقافة أساسي أحادي الطبقة الظهارية المعدة لدراسة تجديد Emma Teal1, Nina G. Steele2, Jayati Chakrabarti1, Loryn Holokai3, Yana Zavros1 1Department of Pharmacology and Systems Physiology, University of Cincinnati, 2Department of Cell & Developmental Biology, University of Michigan, 3Department of Molecular Genetics, Biochemistry & Microbiology, University of Cincinnati JoVE 57435 Immunology and Infection
A Preclinical Human-Derived Autologous Gastric Cancer Organoid/Immune Cell Co-Culture Model to Predict the Efficacy of Targeted Therapies JoVE 61443 Medicine
الفأر والإنسان-المستمدة من الثقافة أساسي أحادي الطبقة الظهارية المعدة لدراسة تجديد Emma Teal1, Nina G. Steele2, Jayati Chakrabarti1, Loryn Holokai3, Yana Zavros1 1Department of Pharmacology and Systems Physiology, University of Cincinnati, 2Department of Cell & Developmental Biology, University of Michigan, 3Department of Molecular Genetics, Biochemistry & Microbiology, University of Cincinnati JoVE 57435 Immunology and Infection
