Yasuyoshi Ouchi Department of Geriatric Medicine, Graduate School of Medicine The University of Tokyo Biography Publications Institution JoVE Articles Yasuyoshi Ouchi has not added a biography. If you are Yasuyoshi Ouchi and would like to personalize this page please email our Author Liaison for assistance. Publications [In Process Citation] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 2015 | Pubmed ID: 25786627 Pregnane X Receptor Knockout Mice Display Aging-dependent Wearing of Articular Cartilage PloS One. 2015 | Pubmed ID: 25749104 Japan As the Front-runner of Super-aged Societies: Perspectives from Medicine and Medical Care in Japan Geriatrics & Gerontology International. Feb, 2015 | Pubmed ID: 25656311 Development of Conversion Formulae Between 4-m, 5-m and 6-m Gait Speed Geriatrics & Gerontology International. Feb, 2015 | Pubmed ID: 25619270 Osteoblast-Specific γ-Glutamyl Carboxylase-Deficient Mice Display Enhanced Bone Formation with Aberrant Mineralization Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2015 | Pubmed ID: 25600070 SLC25A24 As a Novel Susceptibility Gene for Low Fat Mass in Humans and Mice The Journal of Clinical Endocrinology and Metabolism. Apr, 2015 | Pubmed ID: 25599384 Removal of the CPAP Therapy Device During Sleep and Its Association With Body Position Changes and Oxygen Desaturations Respiratory Care. Jan, 2015 | Pubmed ID: 25587170 Metabolic Syndrome, Sarcopenia and Role of Sex and Age: Cross-sectional Analysis of Kashiwa Cohort Study PloS One. 2014 | Pubmed ID: 25405866 Inflammatory Stimuli Induce Inhibitory S-nitrosylation of the Deacetylase SIRT1 to Increase Acetylation and Activation of P53 and P65 Science Signaling. 2014 | Pubmed ID: 25389371 Association of Hearing Loss with Behavioral and Psychological Symptoms in Patients with Dementia Geriatrics & Gerontology International. Jul, 2014 | Pubmed ID: 25065402 Expression of Androgen and Estrogen Signaling Components and Stem Cell Markers to Predict Cancer Progression and Cancer-specific Survival in Patients with Metastatic Prostate Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2014 | Pubmed ID: 24987058 Large-scale Analysis Reveals a Functional Single-nucleotide Polymorphism in the 5'-flanking Region of PRDM16 Gene Associated with Lean Body Mass Aging Cell. May, 2014 | Pubmed ID: 24863034 Pravastatin and Olmesartan Synergistically Ameliorate Renal Failure-induced Vascular Calcification Journal of Atherosclerosis and Thrombosis. 2014 | Pubmed ID: 24834982 Systemic Identification of Estrogen-regulated Genes in Breast Cancer Cells Through Cap Analysis of Gene Expression Mapping Biochemical and Biophysical Research Communications. May, 2014 | Pubmed ID: 24746470 Liver-specific γ-glutamyl Carboxylase-deficient Mice Display Bleeding Diathesis and Short Life Span PloS One. 2014 | Pubmed ID: 24520408 Development of a Simple Screening Test for Sarcopenia in Older Adults Geriatrics & Gerontology International. Feb, 2014 | Pubmed ID: 24450566 Association of Decreased Sympathetic Nervous Activity with Mortality of Older Adults in Long-term Care Geriatrics & Gerontology International. Jan, 2014 | Pubmed ID: 23879364 Vitamin K: Novel Molecular Mechanisms of Action and Its Roles in Osteoporosis Geriatrics & Gerontology International. Jan, 2014 | Pubmed ID: 23530597 Polymorphism of SLC25A32, the Folate Transporter Gene, is Associated with Plasma Folate Levels and Bone Fractures in Japanese Postmenopausal Women Geriatrics & Gerontology International. Dec, 2013 | Pubmed ID: 24354357 Respiratory Dysrhythmia in Dementia with Lewy Bodies: a Cross-sectional Study BMJ Open. 2013 | Pubmed ID: 24022387 Trans-Resveratrol in Gnetum Gnemon Protects Against Oxidative-stress-induced Endothelial Senescence Journal of Natural Products. Jul, 2013 | Pubmed ID: 23859249 Clinical Significance of Amyloid Precursor Protein in Patients with Testicular Germ Cell Tumor Advances in Urology. 2013 | Pubmed ID: 23662100 Androgen-responsive Long Noncoding RNA CTBP1-AS Promotes Prostate Cancer The EMBO Journal. Jun, 2013 | Pubmed ID: 23644382 RNA Sequencing of MCF-7 Breast Cancer Cells Identifies Novel Estrogen-responsive Genes with Functional Estrogen Receptor-binding Sites in the Vicinity of Their Transcription Start Sites Hormones & Cancer. Aug, 2013 | Pubmed ID: 23526455 C-reactive Protein, Bone Strength, and Nine-year Fracture Risk: Data from the Study of Women's Health Across the Nation (SWAN) Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2013 | Pubmed ID: 23456822 Involvement of ASK1-p38 Pathway in the Pathogenesis of Diabetes Triggered by Pancreatic ß Cell Exhaustion Biochimica Et Biophysica Acta. Jun, 2013 | Pubmed ID: 23416061 Priorities of Health Care Outcomes for the Elderly Journal of the American Medical Directors Association. Jul, 2013 | Pubmed ID: 23415841 Intravascular Large B-cell Lymphoma with Symptoms Resembling Progressive Dementia: a Clinical Case Report Journal of the American Geriatrics Society. Feb, 2013 | Pubmed ID: 23405931 Marked Improvement of Elderly Postprandial Hypotension by Dipeptidyl Peptidase IV Inhibitor Geriatrics & Gerontology International. Jan, 2013 | Pubmed ID: 23286563 Acute Exogenous Lipoid Pneumonia Caused by Accidental Kerosene Ingestion in an Elderly Patient with Dementia: a Case Report Geriatrics & Gerontology International. Jan, 2013 | Pubmed ID: 23286561 Thrombomodulin, a Novel Molecule Regulating Inorganic Phosphate-induced Vascular Smooth Muscle Cell Calcification Journal of Molecular and Cellular Cardiology. Mar, 2013 | Pubmed ID: 23274063 [Approaches to Sarcopenia] Clinical Calcium. Jan, 2013 | Pubmed ID: 23268307 [A Case of Collagenous Colitis with Watery Diarrhea Due to Lansoprazole Use in an Elderly Woman] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 2012 | Pubmed ID: 23459656 Ginsenoside Rb1 Prevents MPP(+)-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, P38 MAPK Evidence-based Complementary and Alternative Medicine : ECAM. 2012 | Pubmed ID: 23024694 High Risk of Adverse Drug Reactions in Elderly Patients Taking Six or More Drugs: Analysis of Inpatient Database Geriatrics & Gerontology International. Oct, 2012 | Pubmed ID: 22998384 Gastrointestinal Hemorrhage and Antithrombotic Drug Use in Geriatric Patients Geriatrics & Gerontology International. Oct, 2012 | Pubmed ID: 22998377 14-3-3ζ, a Novel Androgen-responsive Gene, is Upregulated in Prostate Cancer and Promotes Prostate Cancer Cell Proliferation and Survival Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2012 | Pubmed ID: 22904106 The High Frequency of Periodic Limb Movements in Patients with Lewy Body Dementia Journal of Psychiatric Research. Dec, 2012 | Pubmed ID: 22835911 Src Kinase-mediates Androgen Receptor-dependent Non-genomic Activation of Signaling Cascade Leading to Endothelial Nitric Oxide Synthase Biochemical and Biophysical Research Communications. Aug, 2012 | Pubmed ID: 22771325 Factors Associated with Prolonged Hospital Stay in a Geriatric Ward of a University Hospital in Japan Journal of the American Geriatrics Society. Jun, 2012 | Pubmed ID: 22691001 [Therapeutic Purpose and Treatment Guideline of Osteoporosis] Clinical Calcium. Jun, 2012 | Pubmed ID: 22653029 Association of Circulating Sclerostin Levels with Fat Mass and Metabolic Disease--related Markers in Japanese Postmenopausal Women The Journal of Clinical Endocrinology and Metabolism. Aug, 2012 | Pubmed ID: 22639287 Antimicrobial Peptide Defensin: Identification of Novel Isoforms and the Characterization of Their Physiological Roles and Their Significance in the Pathogenesis of Diseases Proceedings of the Japan Academy. Series B, Physical and Biological Sciences. 2012 | Pubmed ID: 22498979 Relationship Between Sleep Apnea and Respiratory Infections in Bedridden Elderly Individuals on Tube Feeding Journal of the American Geriatrics Society. Apr, 2012 | Pubmed ID: 22494290 TACC2 is an Androgen-responsive Cell Cycle Regulator Promoting Androgen-mediated and Castration-resistant Growth of Prostate Cancer Molecular Endocrinology (Baltimore, Md.). May, 2012 | Pubmed ID: 22456197 Lower Physical Activity is a Strong Predictor of Cardiovascular Events in Elderly Patients with Type 2 Diabetes Mellitus Beyond Traditional Risk Factors: the Japanese Elderly Diabetes Intervention Trial Geriatrics & Gerontology International. Apr, 2012 | Pubmed ID: 22435943 Lower Physical Activity, but Not Excessive Calorie Intake, is Associated with Metabolic Syndrome in Elderly with Type 2 Diabetes Mellitus: the Japanese Elderly Diabetes Intervention Trial Geriatrics & Gerontology International. Apr, 2012 | Pubmed ID: 22435942 GPR98/Gpr98 Gene is Involved in the Regulation of Human and Mouse Bone Mineral Density The Journal of Clinical Endocrinology and Metabolism. Apr, 2012 | Pubmed ID: 22419726 Testosterone Deficiency Accelerates Neuronal and Vascular Aging of SAMP8 Mice: Protective Role of ENOS and SIRT1 PloS One. 2012 | Pubmed ID: 22238626 Toward the Realization of a Better Aged Society: Messages from Gerontology and Geriatrics Geriatrics & Gerontology International. Jan, 2012 | Pubmed ID: 22188494 Clinical Significance of Steroid and Xenobiotic Receptor and Its Targeted Gene CYP3A4 in Human Prostate Cancer Cancer Science. Feb, 2012 | Pubmed ID: 22050110 Oct1 Regulates Cell Growth of LNCaP Cells and is a Prognostic Factor for Prostate Cancer International Journal of Cancer. Journal International Du Cancer. Mar, 2012 | Pubmed ID: 21387309 [Transition of Therapeutics in Coronary Artery Disease: Past and Present] Nihon Rinsho. Japanese Journal of Clinical Medicine. Sep, 2011 | Pubmed ID: 22519000 Polypharmacy As a Risk for Fall Occurrence in Geriatric Outpatients Geriatrics & Gerontology International. Dec, 2011 | Pubmed ID: 22212467 PROX1 Suppresses Vitamin K-induced Transcriptional Activity of Steroid and Xenobiotic Receptor Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Nov, 2011 | Pubmed ID: 22023334 Actions of the Japan Geriatric Society in Response to the 2011 off the Pacific Coast of Tohoku Earthquake: First Report Geriatrics & Gerontology International. Oct, 2011 | Pubmed ID: 21951776 Obstructive Sleep Apnea Exacerbates Endothelial Dysfunction in People with Metabolic Syndrome Journal of the American Geriatrics Society. Aug, 2011 | Pubmed ID: 21848831 Pulmonary Features Associated with Being Underweight in Older Men Journal of the American Geriatrics Society. Aug, 2011 | Pubmed ID: 21848827 Sirtuin 1 Retards Hyperphosphatemia-induced Calcification of Vascular Smooth Muscle Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2011 | Pubmed ID: 21719763 ARFGAP3, an Androgen Target Gene, Promotes Prostate Cancer Cell Proliferation and Migration International Journal of Cancer. Journal International Du Cancer. Jun, 2011 | Pubmed ID: 21647875 Association of Polypharmacy with Fall Risk Among Geriatric Outpatients Geriatrics & Gerontology International. Oct, 2011 | Pubmed ID: 21545384 [Inflammatory Control on Lifestyle-related Diseases and Bone Metabolism] Clinical Calcium. May, 2011 | Pubmed ID: 21532119 Risk Stratification Based on Metabolic Syndrome As Well As Non- Metabolic Risk Factors in the Assessment of Carotid Atherosclerosis Journal of Atherosclerosis and Thrombosis. 2011 | Pubmed ID: 21427506 Coronary Artery Calcification and Cerebral Small Vessel Disease. Association of Systemic Atherosclerosis Circulation Journal : Official Journal of the Japanese Circulation Society. 2011 | Pubmed ID: 21178293 Plasma Sex Hormone Levels and Mortality in Disabled Older Men and Women Geriatrics & Gerontology International. Apr, 2011 | Pubmed ID: 21143567 Single-nucleotide Polymorphism in the Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Gene is Associated with Spinal Osteophyte Formation and Disc Degeneration in Japanese Women European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Apr, 2011 | Pubmed ID: 20953637 [Past, Present and Future of Geriatric Education in Japan] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 2010 | Pubmed ID: 21301155 [Can Statins Slow the Process of Vascular Calcification? Possibilities of Lipid-lowering Therapy and Pleiotropic Effect by Statin Treatment] Clinical Calcium. Nov, 2010 | Pubmed ID: 21037393 [Molecular Mechanism of Vascular Aging: Impact of Vascular Smooth Muscle Cell Calcification Via Cellular Senescence] Clinical Calcium. Nov, 2010 | Pubmed ID: 21037384 Pregnane X Receptor Knockout Mice Display Osteopenia with Reduced Bone Formation and Enhanced Bone Resorption The Journal of Endocrinology. Dec, 2010 | Pubmed ID: 20876238 Visceral Fat Accumulation and Metabolic Risk Factor Clustering in Older Adults Journal of the American Geriatrics Society. Sep, 2010 | Pubmed ID: 20863325 Induction of Endothelial Nitric Oxide Synthase, SIRT1, and Catalase by Statins Inhibits Endothelial Senescence Through the Akt Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2010 | Pubmed ID: 20705918 Effects of Testosterone in Older Men with Mild-to-moderate Cognitive Impairment Journal of the American Geriatrics Society. Jul, 2010 | Pubmed ID: 20672465 Identification of Non-synonymous Polymorphisms in the WDSOF1 Gene As Novel Susceptibility Markers for Low Bone Mineral Density in Japanese Postmenopausal Women Bone. Sep, 2010 | Pubmed ID: 20601284 Effects of Dehydroepiandrosterone Supplementation on Cognitive Function and Activities of Daily Living in Older Women with Mild to Moderate Cognitive Impairment Geriatrics & Gerontology International. Oct, 2010 | Pubmed ID: 20497239 Involvement of Androgen Receptor in Nitric Oxide Production Induced by Icariin in Human Umbilical Vein Endothelial Cells FEBS Letters. Jun, 2010 | Pubmed ID: 20416296 Association of Low Testosterone with Metabolic Syndrome and Its Components in Middle-aged Japanese Men Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jun, 2010 | Pubmed ID: 20339372 [A Case of Limbic Encephalitis with Small Cell Lung Carcinoma in Which the Cognitive Function Improved and Redeteriorated During Tumor Therapy] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 2010 | Pubmed ID: 20339211 SIRT1/eNOS Axis As a Potential Target Against Vascular Senescence, Dysfunction and Atherosclerosis Journal of Atherosclerosis and Thrombosis. May, 2010 | Pubmed ID: 20215708 Androgen Receptor-dependent Activation of Endothelial Nitric Oxide Synthase in Vascular Endothelial Cells: Role of Phosphatidylinositol 3-kinase/akt Pathway Endocrinology. Apr, 2010 | Pubmed ID: 20194727 Glucocorticoid-induced Gene Tripartite Motif-containing 63 (TRIM63) Promotes Differentiation of Osteoblastic Cells Endocrine Journal. 2010 | Pubmed ID: 20173306 Differential Expression of Estrogen-related Receptors Beta and Gamma (ERRbeta and ERRgamma) and Their Clinical Significance in Human Prostate Cancer Cancer Science. Mar, 2010 | Pubmed ID: 20128821 Age-related Changes in Plasma Androgen Levels and Their Association with Cardiovascular Risk Factors in Male Japanese Office Workers Geriatrics & Gerontology International. Jan, 2010 | Pubmed ID: 20102380 Androgen Receptor-dependent Transactivation of Growth Arrest-specific Gene 6 Mediates Inhibitory Effects of Testosterone on Vascular Calcification The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 20048160 Aortic Arch Calcification Detectable on Chest X-ray is a Strong Independent Predictor of Cardiovascular Events Beyond Traditional Risk Factors Atherosclerosis. May, 2010 | Pubmed ID: 20006335 Low Testosterone Level As a Predictor of Cardiovascular Events in Japanese Men with Coronary Risk Factors Atherosclerosis. May, 2010 | Pubmed ID: 19963216 Association of HTRA1 Promoter Polymorphism with Spinal Disc Degeneration in Japanese Women Journal of Bone and Mineral Metabolism. Mar, 2010 | Pubmed ID: 19798546 [A Case of a Primary Effusion Lymphoma in the Elderly] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 2009 | Pubmed ID: 20139653 Association of Plasma Sex Hormone Levels with Functional Decline in Elderly Men and Women Geriatrics & Gerontology International. Sep, 2009 | Pubmed ID: 19702939 Association of a Single Nucleotide Polymorphism in the Constitutive Androstane Receptor Gene with Bone Mineral Density Geriatrics & Gerontology International. Sep, 2009 | Pubmed ID: 19702932 A1330V Variant of the Low-density Lipoprotein Receptor-related Protein 5 (LRP5) Gene Decreases Wnt Signaling and Affects the Total Body Bone Mineral Density in Japanese Women Endocrine Journal. 2009 | Pubmed ID: 19571442 Validity and Usefulness of Aortic Arch Calcification in Chest X-ray Journal of Atherosclerosis and Thrombosis. Jun, 2009 | Pubmed ID: 19556724 Vitamin K2 Suppresses Proliferation and Motility of Hepatocellular Carcinoma Cells by Activating Steroid and Xenobiotic Receptor Endocrine Journal. 2009 | Pubmed ID: 19550077 Sirolimus and Everolimus Induce Endothelial Cellular Senescence Via Sirtuin 1 Down-regulation: Therapeutic Implication of Cilostazol After Drug-eluting Stent Implantation Journal of the American College of Cardiology. Jun, 2009 | Pubmed ID: 19520256 Expression of Cytochrome P450 3A4 and Its Clinical Significance in Human Prostate Cancer Urology. Aug, 2009 | Pubmed ID: 19501880 TRIM44 Interacts with and Stabilizes Terf, a TRIM Ubiquitin E3 Ligase Biochemical and Biophysical Research Communications. May, 2009 | Pubmed ID: 19358823 Association of Estrogen Receptor Alpha and Histone Deacetylase 6 Causes Rapid Deacetylation of Tubulin in Breast Cancer Cells Cancer Research. Apr, 2009 | Pubmed ID: 19318565 Bone Mass Effects of a Smad6 Gene Polymorphism in Japanese Postmenopausal Women Journal of Bone and Mineral Metabolism. 2009 | Pubmed ID: 19277452 A Selective Estrogen Receptor Modulator Inhibits TNF-alpha-induced Apoptosis by Activating ERK1/2 Signaling Pathway in Vascular Endothelial Cells Vascular Pharmacology. Jul, 2009 | Pubmed ID: 19275968 Estrogen Receptor-binding Fragment-associated Gene 9 Expression and Its Clinical Significance in Human Testicular Cancer International Journal of Urology : Official Journal of the Japanese Urological Association. Mar, 2009 | Pubmed ID: 19207611 Amyloid Precursor Protein is a Primary Androgen Target Gene That Promotes Prostate Cancer Growth Cancer Research. Jan, 2009 | Pubmed ID: 19117996 Comparison of the Effects of the Kinase Inhibitors Imatinib, Sorafenib, and Transforming Growth Factor-beta Receptor Inhibitor on Extravasation of Nanoparticles from Neovasculature Cancer Science. Jan, 2009 | Pubmed ID: 19037999 EBAG9 is a Tumor-promoting and Prognostic Factor for Bladder Cancer International Journal of Cancer. Journal International Du Cancer. Feb, 2009 | Pubmed ID: 19030177 Airspace Enlargement with Airway Cell Apoptosis in Klotho Mice: a Model of Aging Lung The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Dec, 2008 | Pubmed ID: 19126841 Nocturia in Elderly People with Hypertension--no Influence of Low-dose Thiazide Added to Losartan Journal of the American Geriatrics Society. Nov, 2008 | Pubmed ID: 19016956 [Treatment and Intervention for Sustaining Functional Activities in Community-dwelling Elderly People] Clinical Calcium. Nov, 2008 | Pubmed ID: 18974452 FOXP1 is an Androgen-responsive Transcription Factor That Negatively Regulates Androgen Receptor Signaling in Prostate Cancer Cells Biochemical and Biophysical Research Communications. Sep, 2008 | Pubmed ID: 18640093 Cilostazol Inhibits Oxidative Stress-induced Premature Senescence Via Upregulation of Sirt1 in Human Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2008 | Pubmed ID: 18556572 Antiplatelet Cilostazol, an Inhibitor of Type III Phosphodiesterase, Improves Swallowing Function in Patients with a History of Stroke Journal of the American Geriatrics Society. Jun, 2008 | Pubmed ID: 18554369 Raloxifene Analogue LY117018 Suppresses Oxidative Stress-induced Endothelial Cell Apoptosis Through Activation of ERK1/2 Signaling Pathway European Journal of Pharmacology. Jul, 2008 | Pubmed ID: 18541231 Association of a Single Nucleotide Polymorphism in the Insulin-like Growth Factor-1 Receptor Gene with Spinal Disc Degeneration in Postmenopausal Japanese Women Spine. May, 2008 | Pubmed ID: 18469701 Mechanism of Pi-induced Vascular Calcification Journal of Atherosclerosis and Thrombosis. Apr, 2008 | Pubmed ID: 18385534 Association of Plasma Dehydroepiandrosterone-sulfate Levels with Endothelial Function in Postmenopausal Women with Coronary Risk Factors Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jan, 2008 | Pubmed ID: 18360020 [Paroxetine-induced Hyponatremia in an Elderly Man Due to the Syndrome of Inappropriate Secretion of Antidiuretic Hormone] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Jan, 2008 | Pubmed ID: 18332578 Increase in Oxidative Stress Levels in Elderly Patients with Obstructive Sleep Apnea Syndrome: Effects of Age and Sex Journal of the American Geriatrics Society. Mar, 2008 | Pubmed ID: 18315673 Adiponectin Antagonizes Stimulatory Effect of Tumor Necrosis Factor-alpha on Vascular Smooth Muscle Cell Calcification: Regulation of Growth Arrest-specific Gene 6-mediated Survival Pathway by Adenosine 5'-monophosphate-activated Protein Kinase Endocrinology. Apr, 2008 | Pubmed ID: 18174285 Effect of Nasal Continuous Positive Airway Pressure Treatment on Plasma Adrenomedullin Levels in Patients with Obstructive Sleep Apnea Syndrome: Roles of Nocturnal Hypoxia and Oxidant Stress Hypertension Research : Official Journal of the Japanese Society of Hypertension. Nov, 2007 | Pubmed ID: 18250556 Low Testosterone Level is an Independent Determinant of Endothelial Dysfunction in Men Hypertension Research : Official Journal of the Japanese Society of Hypertension. Nov, 2007 | Pubmed ID: 18250551 [An Elderly Case with Group B Streptococcal Bacteremia, Subcutaneous Abscess and Reactive Polyarthritis] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Nov, 2007 | Pubmed ID: 18198461 Small Intestinal Intussusceptions Caused by Percutaneous Endoscopic Jejunostomy Tube Placement Journal of the American Geriatrics Society. Dec, 2007 | Pubmed ID: 18081681 [A 94-year-old Woman with Nontuberculous Mycobacterium Who Developed Small Intestinal Intussusception Associated with a Percutaneous Endoscopic Jejunostomy Tube] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Sep, 2007 | Pubmed ID: 18049013 Calcitonin Gene-related Peptide Mediates Acid-induced Lung Injury in Mice Respirology (Carlton, Vic.). Nov, 2007 | Pubmed ID: 17986107 Effects of Age and Sex on Plasma Adrenomedullin Levels in Patients with Obstructive Sleep Apnea Syndrome Journal of the American Geriatrics Society. Nov, 2007 | Pubmed ID: 17979911 Sirt1 Modulates Premature Senescence-like Phenotype in Human Endothelial Cells Journal of Molecular and Cellular Cardiology. Nov, 2007 | Pubmed ID: 17916362 [Evaluation of Megatrials with Antihyperlipidemic Agents in Japan] Nihon Rinsho. Japanese Journal of Clinical Medicine. Jul, 2007 | Pubmed ID: 17821901 Primary Role of Functional Ischemia, Quantitative Evidence for the Two-hit Mechanism, and Phosphodiesterase-5 Inhibitor Therapy in Mouse Muscular Dystrophy PloS One. 2007 | Pubmed ID: 17726536 Polymorphisms of Apolipoprotein E and Methylenetetrahydrofolate Reductase in the Japanese Population Journal of Atherosclerosis and Thrombosis. Aug, 2007 | Pubmed ID: 17704619 [Risk Factors Associated with the Duration of Hospitalization in Emergency Admitted Patients with Aspiration Pneumonia] Nihon KokyÅ«ki Gakkai Zasshi = the Journal of the Japanese Respiratory Society. Jul, 2007 | Pubmed ID: 17682462 Association of a Single Nucleotide Polymorphism in the WISP1 Gene with Spinal Osteoarthritis in Postmenopausal Japanese Women Journal of Bone and Mineral Metabolism. 2007 | Pubmed ID: 17593496 [Reproducible Efficacy of Tricyclic Antidepressant on Chronic Pain in an Elderly Patient with Osteoporosis] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Mar, 2007 | Pubmed ID: 17527030 Long-term Oxygen Administration Reduces Plasma Adrenomedullin Levels in Patients with Obstructive Sleep Apnea Syndrome Sleep Medicine. Dec, 2007 | Pubmed ID: 17512795 Cytochrome P450 2B6 is a Growth-inhibitory and Prognostic Factor for Prostate Cancer The Prostate. Jul, 2007 | Pubmed ID: 17455229 Tako-tsubo-like Left Ventricular Dysfunction in a Patient with Chronic Total Occlusion of the Left Anterior Descending Artery International Journal of Cardiology. Jun, 2007 | Pubmed ID: 17434632 Adrenomedullin Insufficiency Increases Allergen-induced Airway Hyperresponsiveness in Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2007 | Pubmed ID: 17332272 Improvement of Cancer-targeting Therapy, Using Nanocarriers for Intractable Solid Tumors by Inhibition of TGF-beta Signaling Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17307870 Increased Expression of Estrogen-related Receptor Alpha (ERRalpha) is a Negative Prognostic Predictor in Human Prostate Cancer International Journal of Cancer. Journal International Du Cancer. Jun, 2007 | Pubmed ID: 17294452 Beta-defensin Overexpression Induces Progressive Muscle Degeneration in Mice American Journal of Physiology. Cell Physiology. Jun, 2007 | Pubmed ID: 17215327 Q89R Polymorphism in the LDL Receptor-related Protein 5 Gene is Associated with Spinal Osteoarthritis in Postmenopausal Japanese Women Spine. Jan, 2007 | Pubmed ID: 17202888 Gas6/Axl-PI3K/Akt Pathway Plays a Central Role in the Effect of Statins on Inorganic Phosphate-induced Calcification of Vascular Smooth Muscle Cells European Journal of Pharmacology. Feb, 2007 | Pubmed ID: 17196959 Signaling Pathway of Nitric Oxide Production Induced by Ginsenoside Rb1 in Human Aortic Endothelial Cells: a Possible Involvement of Androgen Receptor Biochemical and Biophysical Research Communications. Feb, 2007 | Pubmed ID: 17196933 A Functional Single Nucleotide Polymorphism in the Vitamin-K-dependent Gamma-glutamyl Carboxylase Gene (Arg325Gln) is Associated with Bone Mineral Density in Elderly Japanese Women Bone. Feb, 2007 | Pubmed ID: 17029979 Influences of Age, Sex, and LDL-C Change on Cardiovascular Risk Reduction with Pravastatin Treatment in Elderly Japanese Patients: A Post Hoc Analysis of Data from the Pravastatin Anti-atherosclerosis Trial in the Elderly (PATE) Current Therapeutic Research, Clinical and Experimental. Jul, 2006 | Pubmed ID: 24678100 [An Elderly Case with Nontuberculous Mycobacteria Acompanied by Unilateral Massive Pleural Effusion Following the Video-assisted Thoracic Surgery (VATS) for Lung Cancer] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Sep, 2006 | Pubmed ID: 17073297 Reference Values for 6-min Walk Distance in Asian Adults May Not Be Different from That of Caucasian Adults Respirology (Carlton, Vic.). Sep, 2006 | Pubmed ID: 16916347 Prevalence of Metabolic Syndrome in the General Japanese Population in 2000 Journal of Atherosclerosis and Thrombosis. Aug, 2006 | Pubmed ID: 16908953 Pleiotropic Actions of Vitamin K: Protector of Bone Health and Beyond? Nutrition (Burbank, Los Angeles County, Calif.). Jul-Aug, 2006 | Pubmed ID: 16815498 [Atherosclerosis] Nihon Rinsho. Japanese Journal of Clinical Medicine. Apr, 2006 | Pubmed ID: 16689338 Statins Protect Human Aortic Smooth Muscle Cells from Inorganic Phosphate-induced Calcification by Restoring Gas6-Axl Survival Pathway Circulation Research. Apr, 2006 | Pubmed ID: 16556867 Diethylstilbestrol Increases the Density of Prolactin Cells in Male Mouse Pituitary by Inducing Proliferation of Prolactin Cells and Transdifferentiation of Gonadotropic Cells Histochemistry and Cell Biology. Jul, 2006 | Pubmed ID: 16468032 Identification of Novel Steroid Target Genes Through the Combination of Bioinformatics and Functional Analysis of Hormone Response Elements Biochemical and Biophysical Research Communications. Jan, 2006 | Pubmed ID: 16289377 Increased Risk for Cardiovascular Outcomes and Effect of Cholesterol-lowering Pravastatin Therapy in Patients with Diabetes Mellitus in the Pravastatin Anti-atherosclerosis Trial in the Elderly (PATE) Current Therapeutic Research, Clinical and Experimental. Jan, 2005 | Pubmed ID: 24672112 [Sex Difference of Senescence and Diseases in the Elderly the Growing Importance of Gender-specific Geriatric Medicine] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Nov, 2005 | Pubmed ID: 16408497 Tako-tsubo Left Ventricular Dysfunction Caused by a Fall Journal of the American Geriatrics Society. Dec, 2005 | Pubmed ID: 16398918 Polymorphisms in Four Genes Related to Triglyceride and HDL-cholesterol Levels in the General Japanese Population in 2000 Journal of Atherosclerosis and Thrombosis. 2005 | Pubmed ID: 16205020 Estrogen-responsive Finger Protein As a New Potential Biomarker for Breast Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2005 | Pubmed ID: 16144914 [Malignant Lymphoma Manifested by Fever of Unexplained Origin and Pure Red Cell Aplasia in an Elderly Patient] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Jul, 2005 | Pubmed ID: 16117486 Hange-koboku-to, a Kampo Medicine, Modulates Cerebral Levels of 5-HT (5-hydroxytryptamine), NA (noradrenaline) and DA (dopamine) in Mice Phytotherapy Research : PTR. Jun, 2005 | Pubmed ID: 16114091 VEGF-A and FGF-2 Synergistically Promote Neoangiogenesis Through Enhancement of Endogenous PDGF-B-PDGFRbeta Signaling Journal of Cell Science. Aug, 2005 | Pubmed ID: 16105884 Impact of Blood Pressure Variability on Cardiovascular Events in Elderly Patients with Hypertension Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jan, 2005 | Pubmed ID: 15969248 [Epidemiology and Prevention of Elderly Hypertension] Nihon Rinsho. Japanese Journal of Clinical Medicine. Jun, 2005 | Pubmed ID: 15948373 Serum Lipid Survey and Its Recent Trend in the General Japanese Population in 2000 Journal of Atherosclerosis and Thrombosis. 2005 | Pubmed ID: 15942120 Tyrosine Phosphorylation of Paxillin Affects the Metastatic Potential of Human Osteosarcoma Oncogene. Jul, 2005 | Pubmed ID: 15870699 Estrogen Receptor-binding Fragment-associated Antigen 9 is a Tumor-promoting and Prognostic Factor for Renal Cell Carcinoma Cancer Research. May, 2005 | Pubmed ID: 15867365 Association of a Single Nucleotide Polymorphism in the Lipoxygenase ALOX15 5'-flanking Region (-5229G/A) with Bone Mineral Density Journal of Bone and Mineral Metabolism. 2005 | Pubmed ID: 15838625 [The Role of Estrogen in the Regulation of Blood Vessel Function] Nihon Rinsho. Japanese Journal of Clinical Medicine. Mar, 2005 | Pubmed ID: 15813131 Apoptosis of Circulating Neutrophils and Alveolar Macrophages in COPD Chest. Mar, 2005 | Pubmed ID: 15764803 Obstructive Sleep Apnea Causes Systemic Inflammation and Metabolic Syndrome Chest. Mar, 2005 | Pubmed ID: 15764798 Amelioration of Vascular Endothelial Dysfunction in Obstructive Sleep Apnea Syndrome by Nasal Continuous Positive Airway Pressure--possible Involvement of Nitric Oxide and Asymmetric NG, NG-dimethylarginine Circulation Journal : Official Journal of the Japanese Circulation Society. Feb, 2005 | Pubmed ID: 15671617 [Necessity and Role of Geriatric Health Services] Nihon Naika Gakkai Zasshi. The Journal of the Japanese Society of Internal Medicine. Dec, 2004 | Pubmed ID: 15658475 [Right or Wrong of the Hormone Replacement Therapy Involving Osteoporosis] Clinical Calcium. Nov, 2004 | Pubmed ID: 15577164 Analysis of Estrogen Receptor Alpha Signaling Complex at the Plasma Membrane FEBS Letters. Nov, 2004 | Pubmed ID: 15556606 Inhibitory Effect of Low-dose Estrogen on Neointimal Formation After Balloon Injury of Rat Carotid Artery European Journal of Pharmacology. Oct, 2004 | Pubmed ID: 15476753 Association of a Single-nucleotide Polymorphism in Low-density Lipoprotein Receptor-related Protein 5 Gene with Bone Mineral Density Journal of Bone and Mineral Metabolism. 2004 | Pubmed ID: 15221492 Caveolin-1, Id3a and Two LIM Protein Genes Are Upregulated by Estrogen in Vascular Smooth Muscle Cells Life Sciences. Jul, 2004 | Pubmed ID: 15219810 14-3-3sigma is Down-regulated in Human Prostate Cancer Biochemical and Biophysical Research Communications. Jul, 2004 | Pubmed ID: 15184053 Platelet-activating Factor Receptor Develops Airway Hyperresponsiveness Independently of Airway Inflammation in a Murine Asthma Model Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15153532 Increased Plasma Interleukin-6 is Associated with the Pathogenesis of Obstructive Sleep Apnea Syndrome Chest. May, 2004 | Pubmed ID: 15136420 [Tumor Necrosis Factor Receptor(TNFR) Gene Polymorphism] Nihon Rinsho. Japanese Journal of Clinical Medicine. Feb, 2004 | Pubmed ID: 15035120 [TGF-beta] Nihon Rinsho. Japanese Journal of Clinical Medicine. Feb, 2004 | Pubmed ID: 15035099 A Novel Diagnostic Test for the Risk of Aspiration Pneumonia in the Elderly Chest. Feb, 2004 | Pubmed ID: 14769774 Protein Phosphatase 5 is a Negative Regulator of Estrogen Receptor-mediated Transcription Molecular Endocrinology (Baltimore, Md.). May, 2004 | Pubmed ID: 14764652 Diffuse Aspiration Bronchiolitis Due to Achalasia Chest. Jan, 2004 | Pubmed ID: 14718468 Reduced Endothelial Vasomotor Function and Enhanced Neointimal Formation After Vascular Injury in a Rat Model of Blood Pressure Lability Hypertension Research : Official Journal of the Japanese Society of Hypertension. Dec, 2003 | Pubmed ID: 14717342 Depletion of Glutathione S-transferase P1 Induces Apoptosis in Human Lung Fibroblasts Experimental Lung Research. Oct-Nov, 2003 | Pubmed ID: 14710442 Global Burden of COPD in Japan and Asia Lancet. Nov, 2003 | Pubmed ID: 14643136 17 Beta-estradiol Inhibits Cardiac Fibroblast Growth Through Both Subtypes of Estrogen Receptor Biochemical and Biophysical Research Communications. Nov, 2003 | Pubmed ID: 14592435 Oxygen Administration Improves the Serum Level of Nitric Oxide Metabolites in Patients with Obstructive Sleep Apnea Syndrome Sleep Medicine. Sep, 2003 | Pubmed ID: 14592281 Clinical Insignificance of (1-->3)-beta-D-glucan in Early Diagnosis of Invasive Pulmonary Aspergillosis in a Patient with Chronic Obstructive Pulmonary Disease Journal of Medical Microbiology. Nov, 2003 | Pubmed ID: 14532351 Estrogen Receptor Beta Mediates the Inhibitory Effect of Estradiol on Vascular Smooth Muscle Cell Proliferation Cardiovascular Research. Sep, 2003 | Pubmed ID: 14499875 Nosocomial Infections in Adult Intensive-care Units Lancet. Aug, 2003 | Pubmed ID: 12927442 Effects of Oxygen Administration on the Circulating Vascular Endothelial Growth Factor (VEGF) Levels in Patients with Obstructive Sleep Apnea Syndrome Internal Medicine (Tokyo, Japan). Aug, 2003 | Pubmed ID: 12924491 Gastroesophageal Reflux Common in Patients with Sleep Apnea Rather Than Snorers Without Sleep Apnea Chest. Aug, 2003 | Pubmed ID: 12907575 EBAG9/RCAS1 Expression and Its Prognostic Significance in Prostatic Cancer International Journal of Cancer. Journal International Du Cancer. Sep, 2003 | Pubmed ID: 12845666 Clinical Efficacy and Toxicity of Gefitinib in Patients with Lung Cancer Lancet. Jun, 2003 | Pubmed ID: 12801775 Guidelines for Treatment of Hypertension in the Elderly--2002 Revised Version Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jan, 2003 | Pubmed ID: 12661910 Preventing Angiographic Progression of Coronary Atherosclerosis with Pravastatin Journal of Atherosclerosis and Thrombosis. 2003 | Pubmed ID: 12621161 Increased C-reactive Protein and Increased Plasma Interleukin-6 May Synergistically Affect the Progression of Coronary Atherosclerosis in Obstructive Sleep Apnea Syndrome Circulation. Feb, 2003 | Pubmed ID: 12578892 Changing Spectrum of Infective Endocarditis: Review of 194 Episodes over 20 Years Circulation Journal : Official Journal of the Japanese Circulation Society. Jan, 2003 | Pubmed ID: 12520142 A Potent Inhibitor of Cytosolic Phospholipase A2, Arachidonyl Trifluoromethyl Ketone, Attenuates LPS-induced Lung Injury in Mice American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2003 | Pubmed ID: 12505870 Effects of Obstructive Sleep Apnea on Circulating ICAM-1, IL-8, and MCP-1 Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2003 | Pubmed ID: 12391099 Induction of Anti-metallothionein Antibody and Mercury Treatment Decreases Bone Mineral Density in Mice Toxicology and Applied Pharmacology. Dec, 2002 | Pubmed ID: 12490134 Nocturnal Gastroesophageal Reflux: Symptom of Obstructive Sleep Apnea Syndrome in Association with Impaired Swallowing Chest. Dec, 2002 | Pubmed ID: 12475880 Estrogen Activates Cyclin-dependent Kinases 4 and 6 Through Induction of Cyclin D in Rat Primary Osteoblasts Biochemical and Biophysical Research Communications. Nov, 2002 | Pubmed ID: 12437973 Molecular Mechanisms Underlying Human Beta-defensin-2 Gene Expression in a Human Airway Cell Line (LC2/ad) Respirology (Carlton, Vic.). Dec, 2002 | Pubmed ID: 12421237 Attenuation of Antigen-induced Airway Hyperresponsiveness in CGRP-deficient Mice American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2002 | Pubmed ID: 12376349 Identification of Multiple Novel Epididymis-specific Beta-defensin Isoforms in Humans and Mice Journal of Immunology (Baltimore, Md. : 1950). Sep, 2002 | Pubmed ID: 12193721 Mouse Genetic Evidence That Tranilast Reduces Smooth Muscle Cell Hyperplasia Via a P21(WAF1)-dependent Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2002 | Pubmed ID: 12171792 Augmentation of Immune Cell Activity Against Tumor Cells by Rauwolfia Radix Journal of Ethnopharmacology. Aug, 2002 | Pubmed ID: 12127238 Inhibitory Effects of Novel AP-1 Decoy Oligodeoxynucleotides on Vascular Smooth Muscle Cell Proliferation in Vitro and Neointimal Formation in Vivo Circulation Research. Jun, 2002 | Pubmed ID: 12089071 Efp Targets 14-3-3 Sigma for Proteolysis and Promotes Breast Tumour Growth Nature. Jun, 2002 | Pubmed ID: 12075357 [Questionnaire on the Attitude of the Physicians in Educating the Elderly Patients with Chronic Obstructive Pulmonary Disease About Smoking Cessation] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. May, 2002 | Pubmed ID: 12073594 Effect of Red Wine Polyphenols on Vascular Smooth Muscle Cell Function--molecular Mechanism of the 'French Paradox' Mechanisms of Ageing and Development. Apr, 2002 | Pubmed ID: 12044952 Adverse Drug Reactions in Older People with Dementia Journal of the American Geriatrics Society. Feb, 2002 | Pubmed ID: 12028234 Red Wine Polyphenols Inhibit Vascular Smooth Muscle Cell Migration Through Two Distinct Signaling Pathways Circulation. May, 2002 | Pubmed ID: 12021228 A Pivotal Role of Cytosolic Phospholipase A(2) in Bleomycin-induced Pulmonary Fibrosis Nature Medicine. May, 2002 | Pubmed ID: 11984592 [Estrogen Receptor Gene Polymorphism] Nihon Rinsho. Japanese Journal of Clinical Medicine. Mar, 2002 | Pubmed ID: 11979896 [Chronic Obstructive Pulmonary Disease (COPD) in the Elderly: Analysis from Questionnaire About Attitudes to the COPD Guideline of the Japanese Respiratory Society and Actual Therapy for COPD Used by Physicians] Nihon KokyÅ«ki Gakkai Zasshi = the Journal of the Japanese Respiratory Society. Feb, 2002 | Pubmed ID: 11974865 Questionnaire Survey on the Japanese Guidelines for Treatment of Hypertension in the Elderly: 1999 Revised Version Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jan, 2002 | Pubmed ID: 11924729 [Changes of Care Status Before and After the Introduction of the Long-term Care Insurance in Japan--results of Care Status Before the Long-term Care Insurance] Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. Jan, 2002 | Pubmed ID: 11857965 Transient Left Ventricular Apical Ballooning Without Coronary Artery Stenosis: a Form of Stunning-like Phenomenon? Journal of the American College of Cardiology. Feb, 2002 | Pubmed ID: 11849878 Effects of Long-term and Reduced-dose Hormone Replacement Therapy on Endothelial Function and Intima-media Thickness in Postmenopausal Women Menopause (New York, N.Y.). Jan-Feb, 2002 | Pubmed ID: 11791087 Airway Hyperresponsiveness in Transgenic Mice Overexpressing Platelet Activating Factor Receptor is Mediated by an Atropine-sensitive Pathway American Journal of Respiratory and Critical Care Medicine. Jan, 2002 | Pubmed ID: 11790655 במדידה Micro-vivo מחזור בשרירי השלד על ידי מיקרוסקופית תוך חיוני Akihiro Asai1, Nita Sahani1, Yasuyoshi Ouchi2, Jeevendra Martyn1, Shingo Yasuhara1 1Department of Anesthesiology and Critical Care, Shriners Hospital for Children, Massachusetts General Hospital, and Harvard Medical School, 2Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo JoVE 210 Biology
במדידה Micro-vivo מחזור בשרירי השלד על ידי מיקרוסקופית תוך חיוני Akihiro Asai1, Nita Sahani1, Yasuyoshi Ouchi2, Jeevendra Martyn1, Shingo Yasuhara1 1Department of Anesthesiology and Critical Care, Shriners Hospital for Children, Massachusetts General Hospital, and Harvard Medical School, 2Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo JoVE 210 Biology