Yibin Wang

Publications

• Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis
  Frontiers in Cardiovascular Medicine. 2019  |   Pubmed ID: 31417910
• Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure
  JACC. Basic to Translational Science. Jun, 2019  |   Pubmed ID: 31312763
• Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance
  Diabetes. Sep, 2019  |   Pubmed ID: 31167878
• Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure
  JACC. Basic to Translational Science. Apr, 2019  |   Pubmed ID: 31061918
• Effects of Branched-chain Amino Acids on Glucose Metabolism in Obese, Prediabetic Men and Women: a Randomized, Crossover Study
  The American Journal of Clinical Nutrition. Jun, 2019  |   Pubmed ID: 31005973
• Epigenetics in Dilated Cardiomyopathy
  Current Opinion in Cardiology. May, 2019  |   Pubmed ID: 30973397
• RBFox2-miR-34a-Jph2 Axis Contributes to Cardiac Decompensation During Heart Failure
  Proceedings of the National Academy of Sciences of the United States of America. 03, 2019  |   Pubmed ID: 30867288
• Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure
  Circulation Research. Jan, 2019  |   Pubmed ID: 30605412
• Epigenomic Regulation of Heart Failure: Integrating Histone Marks, Long Noncoding RNAs, and Chromatin Architecture
  F1000Research. 2018  |   Pubmed ID: 30416708
• EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs
  Current Gene Therapy. 2018  |   Pubmed ID: 30295189
• Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans
  G3 (Bethesda, Md.). 11, 2018  |   Pubmed ID: 30201759
• Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis
  Circulation. 09, 2018  |   Pubmed ID: 29950403
• Humanin Analog Enhances the Protective Effect of Dexrazoxane Against Doxorubicin-induced Cardiotoxicity
  American Journal of Physiology. Heart and Circulatory Physiology. 09, 2018  |   Pubmed ID: 29775411
• The Serine/threonine-protein Kinase/endoribonuclease IRE1α Protects the Heart Against Pressure Overload-induced Heart Failure
  The Journal of Biological Chemistry. 06, 2018  |   Pubmed ID: 29769316
• A Personalized, Multiomics Approach Identifies Genes Involved in Cardiac Hypertrophy and Heart Failure
  NPJ Systems Biology and Applications. 2018  |   Pubmed ID: 29507758
• A Sarcoplasmic Reticulum Localized Protein Phosphatase Regulates Phospholamban Phosphorylation and Promotes Ischemia Reperfusion Injury in the Heart
  JACC. Basic to Translational Science. Mar, 2017  |   Pubmed ID: 29057374
• Wnt11 Regulates Cardiac Chamber Development and Disease During Perinatal Maturation
  JCI Insight. 09, 2017  |   Pubmed ID: 28878122
• Untangle a Broken Heart Via Janus Kinase 1
  Circulation Research. 09, 2017  |   Pubmed ID: 28860312
• The Calcineurin-FoxO-MuRF1 Signaling Pathway Regulates Myofibril Integrity in Cardiomyocytes
  ELife. 08, 2017  |   Pubmed ID: 28826496
• High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure
  Circulation. Oct, 2017  |   Pubmed ID: 28802249
• Cardiac Myocyte P38α Kinase Regulates Angiogenesis Via Myocyte-endothelial Cell Cross-talk During Stress-induced Remodeling in the Heart
  The Journal of Biological Chemistry. 08, 2017  |   Pubmed ID: 28637870
• A Path to Implement Precision Child Health Cardiovascular Medicine
  Frontiers in Cardiovascular Medicine. 2017  |   Pubmed ID: 28620608
• Inflammatory and Apoptotic Remodeling in Autonomic Nervous System Following Myocardial Infarction
  PloS One. 2017  |   Pubmed ID: 28542617
• A Systems Genetics Approach Identifies As a Link Between Cardiomyocyte Glucose Utilization and Hypertrophic Response
  American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2017  |   Pubmed ID: 28235788
• Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification
  Cell Stem Cell. 02, 2017  |   Pubmed ID: 27867037
• Systems Genetics Approach Identifies Gene Pathways and Adamts2 As Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice
  Cell Systems. Jan, 2017  |   Pubmed ID: 27866946
• Operationalizing Precision Cardiovascular Medicine: Three Innovations
  Circulation Research. 10, 2016  |   Pubmed ID: 27737942
• Deconvolution of the Human Endothelial Transcriptome
  Cell Systems. Sep, 2016  |   Pubmed ID: 27684186
• The Chromatin-binding Protein Smyd1 Restricts Adult Mammalian Heart Growth
  American Journal of Physiology. Heart and Circulatory Physiology. 11, 2016  |   Pubmed ID: 27663768
• Branched Chain Amino Acid Metabolic Reprogramming in Heart Failure
  Biochimica Et Biophysica Acta. 12, 2016  |   Pubmed ID: 27639835
• The Long Noncoding RNA Chaer Defines an Epigenetic Checkpoint in Cardiac Hypertrophy
  Nature Medicine. 10, 2016  |   Pubmed ID: 27618650
• Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery
  Circulation. Cardiovascular Genetics. Oct, 2016  |   Pubmed ID: 27591185
• Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model
  PLoS Genetics. Jul, 2016  |   Pubmed ID: 27385019
• Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA
  Organic Letters. 06, 2016  |   Pubmed ID: 27191599
• The Hybrid Mouse Diversity Panel: a Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits
  Journal of Lipid Research. Jun, 2016  |   Pubmed ID: 27099397
• Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure
  Circulation. May, 2016  |   Pubmed ID: 27059949
• Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy
  Hypertension (Dallas, Tex. : 1979). May, 2016  |   Pubmed ID: 27021013
• DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States
  Circulation Research. Mar, 2016  |   Pubmed ID: 26838786
• P38 MAP Kinases in the Heart
  Gene. Jan, 2016  |   Pubmed ID: 26390817
• M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production
  Scientific Reports. Nov, 2015  |   Pubmed ID: 26615759
• The Elusive Philosopher's Stone in Young Blood
  Circulation Research. Nov, 2015  |   Pubmed ID: 26541677
• Activation of Notch3 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation Via Hes1/p27Kip1 Signaling Pathway
  FEBS Open Bio. 2015  |   Pubmed ID: 26380809
• Deletion of MLIP (muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation
  The Journal of Biological Chemistry. Oct, 2015  |   Pubmed ID: 26359501
• A H(a)rd Way to Adapt in Cardiac Hypertrophy
  Circulation Research. Aug, 2015  |   Pubmed ID: 26316602
• The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets
  Journal of Cardiothoracic and Vascular Anesthesia. Oct, 2015  |   Pubmed ID: 25976605
• Hypertrophic Preconditioning: Short-term Tricks for Long-term Gain
  Circulation. Apr, 2015  |   Pubmed ID: 25820337
• Genetics of Common Forms of Heart Failure: Challenges and Potential Solutions
  Current Opinion in Cardiology. May, 2015  |   Pubmed ID: 25768955
• Dawn of the Epi-LncRNAs: New Path from Myheart
  Circulation Research. Jan, 2015  |   Pubmed ID: 25593274
• Mapping Genetic Contributions to Cardiac Pathology Induced by Beta-adrenergic Stimulation in Mice
  Circulation. Cardiovascular Genetics. Feb, 2015  |   Pubmed ID: 25480693
• Repression of Sox9 by Jag1 is Continuously Required to Suppress the Default Chondrogenic Fate of Vascular Smooth Muscle Cells
  Developmental Cell. Dec, 2014  |   Pubmed ID: 25535917
• IRE1 Phosphatase PP2Ce Regulates Adaptive ER Stress Response in the Postpartum Mammary Gland
  PloS One. 2014  |   Pubmed ID: 25369058
• Blind Dates in Sciences: Dealing with Rejection in Peer Review
  Circulation Research. Mar, 2014  |   Pubmed ID: 24625725
• Decoding the Noncoding Transcripts in Human Heart Failure
  Circulation. Mar, 2014  |   Pubmed ID: 24429689
• Interferon Regulatory Factors in Heart: Stress Response Beyond Inflammation
  Hypertension (Dallas, Tex. : 1979). Apr, 2014  |   Pubmed ID: 24396026
• Systems Proteomics of Cardiac Chromatin Identifies Nucleolin As a Regulator of Growth and Cellular Plasticity in Cardiomyocytes
  American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2013  |   Pubmed ID: 24077883
• Mechanism-based Engineering Against Anthracycline Cardiotoxicity
  Circulation. Jul, 2013  |   Pubmed ID: 23757311
• Nuclear Phosphatase PPM1G in Cellular Survival and Neural Development
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2013  |   Pubmed ID: 23723158
• Endothelial Deletion of Murine Jag1 Leads to Valve Calcification and Congenital Heart Defects Associated with Alagille Syndrome
  Development (Cambridge, England). Dec, 2012  |   Pubmed ID: 23095891
• Hybrid Mouse Diversity Panel: a Panel of Inbred Mouse Strains Suitable for Analysis of Complex Genetic Traits
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Oct, 2012  |   Pubmed ID: 22892838
• Global Impact of RNA Splicing on Transcriptome Remodeling in the Heart
  Journal of Zhejiang University. Science. B. Aug, 2012  |   Pubmed ID: 22843179
• Prostaglandin E2 in Remote Control of Myocardial Remodeling
  Circulation. Jun, 2012  |   Pubmed ID: 22589382
• 染色质蛋白质在疾病中的量化分析揭示了重构的原则，并将高迁移率族蛋白 B2 标识为调节器的肥厚的增长。
  Molecular & Cellular Proteomics : MCP. Jan, 2012  |   Pubmed ID: 22270000
• P38γ Activity is Required for Maintenance of Slow Skeletal Muscle Size
  Muscle & Nerve. Feb, 2012  |   Pubmed ID: 22246884
• Systems-based Approaches to Cardiovascular Disease
  Nature Reviews. Cardiology. Jan, 2012  |   Pubmed ID: 22231714
• Cdc37/Hsp90 Protein-mediated Regulation of IRE1α Protein Activity in Endoplasmic Reticulum Stress Response and Insulin Synthesis in INS-1 Cells
  The Journal of Biological Chemistry. Feb, 2012  |   Pubmed ID: 22199355
• Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts
  Circulation Research. Dec, 2011  |   Pubmed ID: 22034492
• Restriction of Big Hearts by a Small RNA
  Circulation Research. Feb, 2011  |   Pubmed ID: 21293005
• Absence of Progeria-like Disease Phenotypes in Knock-in Mice Expressing a Non-farnesylated Version of Progerin
  Human Molecular Genetics. Feb, 2011  |   Pubmed ID: 21088111
• Mitogen-activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-breaking Tale
  Physiological Reviews. Oct, 2010  |   Pubmed ID: 20959622
• Electrochemical Properties and Myocyte Interaction of Carbon Nanotube Microelectrodes
  Nano Letters. Nov, 2010  |   Pubmed ID: 20954739
• Differential Regulation of Proteasome Function in Isoproterenol-induced Cardiac Hypertrophy
  Circulation Research. Oct, 2010  |   Pubmed ID: 20814020
• Targeted Disruption of Mapk14 (p38MAPKalpha) in Granulosa Cells and Cumulus Cells Causes Cell-specific Changes in Gene Expression Profiles That Rescue COC Expansion and Maintain Fertility
  Molecular Endocrinology (Baltimore, Md.). Sep, 2010  |   Pubmed ID: 20610537
• 非 Farnesylated Prelamin A 的积累会导致心肌病，但没有一例。
  Human Molecular Genetics. Jul, 2010  |   Pubmed ID: 20421363
• MAPK-activated Protein Kinase-2 in Cardiac Hypertrophy and Cyclooxygenase-2 Regulation in Heart
  Circulation Research. Apr, 2010  |   Pubmed ID: 20339119
• Specific Regulation of Noncanonical P38alpha Activation by Hsp90-Cdc37 Chaperone Complex in Cardiomyocyte
  Circulation Research. Apr, 2010  |   Pubmed ID: 20299663
• Compensatory Hypertrophy Induced by Ventricular Cardiomyocyte-specific COX-2 Expression in Mice
  Journal of Molecular and Cellular Cardiology. Jul, 2010  |   Pubmed ID: 20170663
• Calsarcin-1 压力超负荷致心肌肥大过程及其类似物调节。
  Journal of Molecular and Cellular Cardiology. Jun, 2010  |   Pubmed ID: 20170660
• Mice Carrying a Conditional Serca2(flox) Allele for the Generation of Ca(2+) Handling-deficient Mouse Models
  Cell Calcium. Sep, 2009  |   Pubmed ID: 19692123
• Inducible and Cardiac Specific PTEN Inactivation Protects Ischemia/reperfusion Injury
  Journal of Molecular and Cellular Cardiology. Feb, 2009  |   Pubmed ID: 19038262
• 斑马鱼作为心血管发育和疾病模式。
  Drug Discovery Today. Disease Models. 2008  |   Pubmed ID: 22275951
• 蛋白质组学研究心肌细胞死亡和生存的见解。
  Proteomics. Clinical Applications. Jun, 2008  |   Pubmed ID: 21136883
• Mitogen-activated Protein Kinases in Heart Development and Diseases
  Circulation. Sep, 2007  |   Pubmed ID: 17875982
• Gi Alpha 1 介导心脏电生理重构和肥厚型心肌病心律失常。
  Circulation. Aug, 2007  |   Pubmed ID: 17646583
• A Novel Mitochondrial Matrix Serine/threonine Protein Phosphatase Regulates the Mitochondria Permeability Transition Pore and is Essential for Cellular Survival and Development
  Genes & Development. Apr, 2007  |   Pubmed ID: 17374715
• Role of an Alternatively Spliced Form of AlphaII-spectrin in Localization of Connexin 43 in Cardiomyocytes and Regulation by Stress-activated Protein Kinase
  Journal of Molecular and Cellular Cardiology. Mar, 2007  |   Pubmed ID: 17276456
• Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth
  The Journal of Biological Chemistry. Sep, 2006  |   Pubmed ID: 16798733
• JNK Activation Decreases PP2A Regulatory Subunit B56alpha Expression and MRNA Stability and Increases AUF1 Expression in Cardiomyocytes
  American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2006  |   Pubmed ID: 16603688
• Cholesterol-induced Macrophage Apoptosis Requires ER Stress Pathways and Engagement of the Type A Scavenger Receptor
  The Journal of Cell Biology. Oct, 2005  |   Pubmed ID: 16203857
• Molecular and Functional Signature of Heart Hypertrophy During Pregnancy
  Circulation Research. Jun, 2005  |   Pubmed ID: 15905459
• P38 MAP Kinase Inhibition Enables Proliferation of Adult Mammalian Cardiomyocytes
  Genes & Development. May, 2005  |   Pubmed ID: 15870258
• Oxidant Stress from Nitric Oxide Synthase-3 Uncoupling Stimulates Cardiac Pathologic Remodeling from Chronic Pressure Load
  The Journal of Clinical Investigation. May, 2005  |   Pubmed ID: 15841206
• 一氧化氮捐助者保护小鼠心肌梗死通过调制的线粒体通透性转变。
  American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2005  |   Pubmed ID: 15528225
• Return of Calcium: Manipulating Intracellular Calcium to Prevent Cardiac Pathologies
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004  |   Pubmed ID: 15079064
• Stress-activated MAP Kinases in Cardiac Remodeling and Heart Failure; New Insights from Transgenic Studies
  Trends in Cardiovascular Medicine. Feb, 2004  |   Pubmed ID: 15030789
• Chronic Suppression of Heart-failure Progression by a Pseudophosphorylated Mutant of Phospholamban Via in Vivo Cardiac RAAV Gene Delivery
  Nature Medicine. Aug, 2002  |   Pubmed ID: 12134142
• RelB Modulation of IkappaBalpha Stability As a Mechanism of Transcription Suppression of Interleukin-1alpha (IL-1alpha), IL-1beta, and Tumor Necrosis Factor Alpha in Fibroblasts
  Molecular and Cellular Biology. Nov, 1999  |   Pubmed ID: 10523657
• Enhanced Galphaq Signaling: a Common Pathway Mediates Cardiac Hypertrophy and Apoptotic Heart Failure
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 1998  |   Pubmed ID: 9707614