Yibin Wang Department of Anesthesiology University of California Biography Publications Institution JoVE Articles Yibin Wang has not added a biography. If you are Yibin Wang and would like to personalize this page please email our Author Liaison for assistance. Publications Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis Frontiers in Cardiovascular Medicine. 2019 | Pubmed ID: 31417910 Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure JACC. Basic to Translational Science. Jun, 2019 | Pubmed ID: 31312763 Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance Diabetes. Sep, 2019 | Pubmed ID: 31167878 Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure JACC. Basic to Translational Science. Apr, 2019 | Pubmed ID: 31061918 Effects of Branched-chain Amino Acids on Glucose Metabolism in Obese, Prediabetic Men and Women: a Randomized, Crossover Study The American Journal of Clinical Nutrition. Jun, 2019 | Pubmed ID: 31005973 Epigenetics in Dilated Cardiomyopathy Current Opinion in Cardiology. May, 2019 | Pubmed ID: 30973397 RBFox2-miR-34a-Jph2 Axis Contributes to Cardiac Decompensation During Heart Failure Proceedings of the National Academy of Sciences of the United States of America. 03, 2019 | Pubmed ID: 30867288 Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure Circulation Research. Jan, 2019 | Pubmed ID: 30605412 Epigenomic Regulation of Heart Failure: Integrating Histone Marks, Long Noncoding RNAs, and Chromatin Architecture F1000Research. 2018 | Pubmed ID: 30416708 EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs Current Gene Therapy. 2018 | Pubmed ID: 30295189 Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans G3 (Bethesda, Md.). 11, 2018 | Pubmed ID: 30201759 Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis Circulation. 09, 2018 | Pubmed ID: 29950403 Humanin Analog Enhances the Protective Effect of Dexrazoxane Against Doxorubicin-induced Cardiotoxicity American Journal of Physiology. Heart and Circulatory Physiology. 09, 2018 | Pubmed ID: 29775411 The Serine/threonine-protein Kinase/endoribonuclease IRE1α Protects the Heart Against Pressure Overload-induced Heart Failure The Journal of Biological Chemistry. 06, 2018 | Pubmed ID: 29769316 A Personalized, Multiomics Approach Identifies Genes Involved in Cardiac Hypertrophy and Heart Failure NPJ Systems Biology and Applications. 2018 | Pubmed ID: 29507758 A Sarcoplasmic Reticulum Localized Protein Phosphatase Regulates Phospholamban Phosphorylation and Promotes Ischemia Reperfusion Injury in the Heart JACC. Basic to Translational Science. Mar, 2017 | Pubmed ID: 29057374 Wnt11 Regulates Cardiac Chamber Development and Disease During Perinatal Maturation JCI Insight. 09, 2017 | Pubmed ID: 28878122 Untangle a Broken Heart Via Janus Kinase 1 Circulation Research. 09, 2017 | Pubmed ID: 28860312 The Calcineurin-FoxO-MuRF1 Signaling Pathway Regulates Myofibril Integrity in Cardiomyocytes ELife. 08, 2017 | Pubmed ID: 28826496 High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure Circulation. Oct, 2017 | Pubmed ID: 28802249 Cardiac Myocyte P38α Kinase Regulates Angiogenesis Via Myocyte-endothelial Cell Cross-talk During Stress-induced Remodeling in the Heart The Journal of Biological Chemistry. 08, 2017 | Pubmed ID: 28637870 A Path to Implement Precision Child Health Cardiovascular Medicine Frontiers in Cardiovascular Medicine. 2017 | Pubmed ID: 28620608 Inflammatory and Apoptotic Remodeling in Autonomic Nervous System Following Myocardial Infarction PloS One. 2017 | Pubmed ID: 28542617 A Systems Genetics Approach Identifies As a Link Between Cardiomyocyte Glucose Utilization and Hypertrophic Response American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2017 | Pubmed ID: 28235788 Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification Cell Stem Cell. 02, 2017 | Pubmed ID: 27867037 Systems Genetics Approach Identifies Gene Pathways and Adamts2 As Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice Cell Systems. Jan, 2017 | Pubmed ID: 27866946 Operationalizing Precision Cardiovascular Medicine: Three Innovations Circulation Research. 10, 2016 | Pubmed ID: 27737942 Deconvolution of the Human Endothelial Transcriptome Cell Systems. Sep, 2016 | Pubmed ID: 27684186 The Chromatin-binding Protein Smyd1 Restricts Adult Mammalian Heart Growth American Journal of Physiology. Heart and Circulatory Physiology. 11, 2016 | Pubmed ID: 27663768 Branched Chain Amino Acid Metabolic Reprogramming in Heart Failure Biochimica Et Biophysica Acta. 12, 2016 | Pubmed ID: 27639835 The Long Noncoding RNA Chaer Defines an Epigenetic Checkpoint in Cardiac Hypertrophy Nature Medicine. 10, 2016 | Pubmed ID: 27618650 Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery Circulation. Cardiovascular Genetics. Oct, 2016 | Pubmed ID: 27591185 Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model PLoS Genetics. Jul, 2016 | Pubmed ID: 27385019 Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA Organic Letters. 06, 2016 | Pubmed ID: 27191599 The Hybrid Mouse Diversity Panel: a Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits Journal of Lipid Research. Jun, 2016 | Pubmed ID: 27099397 Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure Circulation. May, 2016 | Pubmed ID: 27059949 Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy Hypertension (Dallas, Tex. : 1979). May, 2016 | Pubmed ID: 27021013 DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States Circulation Research. Mar, 2016 | Pubmed ID: 26838786 P38 MAP Kinases in the Heart Gene. Jan, 2016 | Pubmed ID: 26390817 M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production Scientific Reports. Nov, 2015 | Pubmed ID: 26615759 The Elusive Philosopher's Stone in Young Blood Circulation Research. Nov, 2015 | Pubmed ID: 26541677 Activation of Notch3 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation Via Hes1/p27Kip1 Signaling Pathway FEBS Open Bio. 2015 | Pubmed ID: 26380809 Deletion of MLIP (muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation The Journal of Biological Chemistry. Oct, 2015 | Pubmed ID: 26359501 A H(a)rd Way to Adapt in Cardiac Hypertrophy Circulation Research. Aug, 2015 | Pubmed ID: 26316602 The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets Journal of Cardiothoracic and Vascular Anesthesia. Oct, 2015 | Pubmed ID: 25976605 Hypertrophic Preconditioning: Short-term Tricks for Long-term Gain Circulation. Apr, 2015 | Pubmed ID: 25820337 Genetics of Common Forms of Heart Failure: Challenges and Potential Solutions Current Opinion in Cardiology. May, 2015 | Pubmed ID: 25768955 Dawn of the Epi-LncRNAs: New Path from Myheart Circulation Research. Jan, 2015 | Pubmed ID: 25593274 Mapping Genetic Contributions to Cardiac Pathology Induced by Beta-adrenergic Stimulation in Mice Circulation. Cardiovascular Genetics. Feb, 2015 | Pubmed ID: 25480693 Repression of Sox9 by Jag1 is Continuously Required to Suppress the Default Chondrogenic Fate of Vascular Smooth Muscle Cells Developmental Cell. Dec, 2014 | Pubmed ID: 25535917 IRE1 Phosphatase PP2Ce Regulates Adaptive ER Stress Response in the Postpartum Mammary Gland PloS One. 2014 | Pubmed ID: 25369058 Blind Dates in Sciences: Dealing with Rejection in Peer Review Circulation Research. Mar, 2014 | Pubmed ID: 24625725 Decoding the Noncoding Transcripts in Human Heart Failure Circulation. Mar, 2014 | Pubmed ID: 24429689 Interferon Regulatory Factors in Heart: Stress Response Beyond Inflammation Hypertension (Dallas, Tex. : 1979). Apr, 2014 | Pubmed ID: 24396026 Systems Proteomics of Cardiac Chromatin Identifies Nucleolin As a Regulator of Growth and Cellular Plasticity in Cardiomyocytes American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2013 | Pubmed ID: 24077883 Mechanism-based Engineering Against Anthracycline Cardiotoxicity Circulation. Jul, 2013 | Pubmed ID: 23757311 Nuclear Phosphatase PPM1G in Cellular Survival and Neural Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2013 | Pubmed ID: 23723158 Endothelial Deletion of Murine Jag1 Leads to Valve Calcification and Congenital Heart Defects Associated with Alagille Syndrome Development (Cambridge, England). Dec, 2012 | Pubmed ID: 23095891 Hybrid Mouse Diversity Panel: a Panel of Inbred Mouse Strains Suitable for Analysis of Complex Genetic Traits Mammalian Genome : Official Journal of the International Mammalian Genome Society. Oct, 2012 | Pubmed ID: 22892838 Global Impact of RNA Splicing on Transcriptome Remodeling in the Heart Journal of Zhejiang University. Science. B. Aug, 2012 | Pubmed ID: 22843179 Prostaglandin E2 in Remote Control of Myocardial Remodeling Circulation. Jun, 2012 | Pubmed ID: 22589382 Quantitative Analysis of the Chromatin Proteome in Disease Reveals Remodeling Principles and Identifies High Mobility Group Protein B2 As a Regulator of Hypertrophic Growth Molecular & Cellular Proteomics : MCP. Jan, 2012 | Pubmed ID: 22270000 P38γ Activity is Required for Maintenance of Slow Skeletal Muscle Size Muscle & Nerve. Feb, 2012 | Pubmed ID: 22246884 Systems-based Approaches to Cardiovascular Disease Nature Reviews. Cardiology. Jan, 2012 | Pubmed ID: 22231714 Cdc37/Hsp90 Protein-mediated Regulation of IRE1α Protein Activity in Endoplasmic Reticulum Stress Response and Insulin Synthesis in INS-1 Cells The Journal of Biological Chemistry. Feb, 2012 | Pubmed ID: 22199355 Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts Circulation Research. Dec, 2011 | Pubmed ID: 22034492 Restriction of Big Hearts by a Small RNA Circulation Research. Feb, 2011 | Pubmed ID: 21293005 Absence of Progeria-like Disease Phenotypes in Knock-in Mice Expressing a Non-farnesylated Version of Progerin Human Molecular Genetics. Feb, 2011 | Pubmed ID: 21088111 Mitogen-activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-breaking Tale Physiological Reviews. Oct, 2010 | Pubmed ID: 20959622 Electrochemical Properties and Myocyte Interaction of Carbon Nanotube Microelectrodes Nano Letters. Nov, 2010 | Pubmed ID: 20954739 Differential Regulation of Proteasome Function in Isoproterenol-induced Cardiac Hypertrophy Circulation Research. Oct, 2010 | Pubmed ID: 20814020 Targeted Disruption of Mapk14 (p38MAPKalpha) in Granulosa Cells and Cumulus Cells Causes Cell-specific Changes in Gene Expression Profiles That Rescue COC Expansion and Maintain Fertility Molecular Endocrinology (Baltimore, Md.). Sep, 2010 | Pubmed ID: 20610537 An Accumulation of Non-farnesylated Prelamin A Causes Cardiomyopathy but Not Progeria Human Molecular Genetics. Jul, 2010 | Pubmed ID: 20421363 MAPK-activated Protein Kinase-2 in Cardiac Hypertrophy and Cyclooxygenase-2 Regulation in Heart Circulation Research. Apr, 2010 | Pubmed ID: 20339119 Specific Regulation of Noncanonical P38alpha Activation by Hsp90-Cdc37 Chaperone Complex in Cardiomyocyte Circulation Research. Apr, 2010 | Pubmed ID: 20299663 Compensatory Hypertrophy Induced by Ventricular Cardiomyocyte-specific COX-2 Expression in Mice Journal of Molecular and Cellular Cardiology. Jul, 2010 | Pubmed ID: 20170663 Post-translational Regulation of Calsarcin-1 During Pressure Overload-induced Cardiac Hypertrophy Journal of Molecular and Cellular Cardiology. Jun, 2010 | Pubmed ID: 20170660 Mice Carrying a Conditional Serca2(flox) Allele for the Generation of Ca(2+) Handling-deficient Mouse Models Cell Calcium. Sep, 2009 | Pubmed ID: 19692123 Inducible and Cardiac Specific PTEN Inactivation Protects Ischemia/reperfusion Injury Journal of Molecular and Cellular Cardiology. Feb, 2009 | Pubmed ID: 19038262 Zebrafish As a Model for Cardiovascular Development and Disease Drug Discovery Today. Disease Models. 2008 | Pubmed ID: 22275951 Proteomic Insights into Cardiac Cell Death and Survival Proteomics. Clinical Applications. Jun, 2008 | Pubmed ID: 21136883 Mitogen-activated Protein Kinases in Heart Development and Diseases Circulation. Sep, 2007 | Pubmed ID: 17875982 Gi Alpha 1-mediated Cardiac Electrophysiological Remodeling and Arrhythmia in Hypertrophic Cardiomyopathy Circulation. Aug, 2007 | Pubmed ID: 17646583 A Novel Mitochondrial Matrix Serine/threonine Protein Phosphatase Regulates the Mitochondria Permeability Transition Pore and is Essential for Cellular Survival and Development Genes & Development. Apr, 2007 | Pubmed ID: 17374715 Role of an Alternatively Spliced Form of AlphaII-spectrin in Localization of Connexin 43 in Cardiomyocytes and Regulation by Stress-activated Protein Kinase Journal of Molecular and Cellular Cardiology. Mar, 2007 | Pubmed ID: 17276456 Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16798733 JNK Activation Decreases PP2A Regulatory Subunit B56alpha Expression and MRNA Stability and Increases AUF1 Expression in Cardiomyocytes American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2006 | Pubmed ID: 16603688 Cholesterol-induced Macrophage Apoptosis Requires ER Stress Pathways and Engagement of the Type A Scavenger Receptor The Journal of Cell Biology. Oct, 2005 | Pubmed ID: 16203857 Molecular and Functional Signature of Heart Hypertrophy During Pregnancy Circulation Research. Jun, 2005 | Pubmed ID: 15905459 P38 MAP Kinase Inhibition Enables Proliferation of Adult Mammalian Cardiomyocytes Genes & Development. May, 2005 | Pubmed ID: 15870258 Oxidant Stress from Nitric Oxide Synthase-3 Uncoupling Stimulates Cardiac Pathologic Remodeling from Chronic Pressure Load The Journal of Clinical Investigation. May, 2005 | Pubmed ID: 15841206 Nitric Oxide Donors Protect Murine Myocardium Against Infarction Via Modulation of Mitochondrial Permeability Transition American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2005 | Pubmed ID: 15528225 Return of Calcium: Manipulating Intracellular Calcium to Prevent Cardiac Pathologies Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004 | Pubmed ID: 15079064 Stress-activated MAP Kinases in Cardiac Remodeling and Heart Failure; New Insights from Transgenic Studies Trends in Cardiovascular Medicine. Feb, 2004 | Pubmed ID: 15030789 Chronic Suppression of Heart-failure Progression by a Pseudophosphorylated Mutant of Phospholamban Via in Vivo Cardiac RAAV Gene Delivery Nature Medicine. Aug, 2002 | Pubmed ID: 12134142 RelB Modulation of IkappaBalpha Stability As a Mechanism of Transcription Suppression of Interleukin-1alpha (IL-1alpha), IL-1beta, and Tumor Necrosis Factor Alpha in Fibroblasts Molecular and Cellular Biology. Nov, 1999 | Pubmed ID: 10523657 Enhanced Galphaq Signaling: a Common Pathway Mediates Cardiac Hypertrophy and Apoptotic Heart Failure Proceedings of the National Academy of Sciences of the United States of America. Aug, 1998 | Pubmed ID: 9707614 Имплантация изопротеренола Мини-насоса, чтобы вызвать сердечную недостаточность у мышей Shuxun Ren1, Sunny Chang2, Alex Tran3, Arianna Mandelli4, Yibin Wang1, Jessica J. Wang2 1Department of Anesthesiology, University of California, 2Department of Medicine, University of California, 3Department of Microbiology, Immunology & Molecular Genetics, University of California, 4Department of Molecular, Cell, and Developmental Biology, University of California JoVE 59646 Medicine
Имплантация изопротеренола Мини-насоса, чтобы вызвать сердечную недостаточность у мышей Shuxun Ren1, Sunny Chang2, Alex Tran3, Arianna Mandelli4, Yibin Wang1, Jessica J. Wang2 1Department of Anesthesiology, University of California, 2Department of Medicine, University of California, 3Department of Microbiology, Immunology & Molecular Genetics, University of California, 4Department of Molecular, Cell, and Developmental Biology, University of California JoVE 59646 Medicine
