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Articles by Zheng Ser in JoVE
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A Strategy for Sensitive, Large Scale Quantitative Metabolomics
Xiaojing Liu1, Zheng Ser1, Ahmad A. Cluntun1,2, Samantha J. Mentch1,2, Jason W. Locasale1,2
1Division of Nutritional Sciences, Cornell University, 2Field of Biochemistry, and Molecular Cell Biology, Cornell University
Metabolite profiling has been a valuable asset in the study of metabolism in health and disease. Utilizing normal-phased liquid chromatography coupled to high-resolution mass spectrometry with polarity switching and a rapid duty cycle, we describe a protocol to analyze the polar metabolic composition of biological material with high sensitivity, accuracy, and resolution.
Other articles by Zheng Ser on PubMed
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