Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove

Evaluating Murine BBB Disruption Induced by Hypoxic Human Placenta-Derived sEVs

January 26th, 2024
*1, *1,2, 1, 3, 3,4, 1, 5, 1, 1, 1,6
1Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, Chillan, 2Nursery School, Health Faculty, Universidad Santo Tomás, Los Angeles, 3Obstetrics and Gynecology Department, Herminda Martin Clinical Hospital, Chillan, 4Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepcion, 5Laboratory of Animal Biotechnology, Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepción, Chillan, 6Group of Research and Innovation in Vascular Health (GRIVAS Health), Chillan
* These authors contributed equally

Summary
Automatic Translation

Se presenta un protocolo para evaluar si los pequeños VE (sEV) aislados de explantes placentarios cultivados en condiciones hipóxicas (modelando un aspecto de la preeclampsia) alteran la barrera hematoencefálica en ratones hembra adultos no preñados.

Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter