Vienna Hepatic Hemodynamic Laboratory 1 article published in JoVE Medicine Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats Philipp Königshofer1,2, Ksenia Brusilovskaya1,2, Philipp Schwabl1,2, Bruno K. Podesser3, Michael Trauner1, Thomas Reiberger1,2 1Div. of Gastroenterology and Hepatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 2Vienna Hepatic Hemodynamic Laboratory, Medical University of Vienna, Vienna, Austria, 3Center of Biomedical Research, Medical University of Vienna, Vienna, Austria Here we describe a detailed protocol for invasive measurements of hemodynamic parameters including portal pressure, splanchnic blood flow, and systemic hemodynamics in order to characterize the portal hypertensive syndrome in rats.