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In vivo billeddannelse af tumorangiogenese hjælp Fluorescens Confocal Videomicroscopy

Article DOI: 10.3791/50347-v • 05:08 min • September 11th, 2013
September 11th, 2013 •
1, 1, 1,2, 1,2, 1,2, 1,2
1Université Paris Descartes Sorbonne Paris Cité, INSERM UMR-S970, 2Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Radiologie

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I dette papir, præsenterer vi en metode til at analysere tumor mikrokar in vivo ved hjælp af dynamisk kontrast-forstærkede fluorescens videomicroscopy. To kvantitative parametre blev erhvervet: funktionel kapillartæthed afspejler vaskularisering af tumoren, og indeks lækage afspejler utætheder af endotel væg.

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Medicine kræft biologiske Microcirculation optisk afbildningsindretninger (design og teknikker) Confocal videomicroscopy mikrocirkulationen kapillær lækage FITC-dextran angiogenese
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