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JoVE Journal Bioengineering
Produksjon, karakterisering og potensielle bruk av en 3D Tissue-konstruert Menneskelig Esophageal slimhinnene Model
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Produksjon, karakterisering og potensielle bruk av en 3D Tissue-konstruert Menneskelig Esophageal slimhinnene Model

Article DOI: 10.3791/52693-v • 12:16 min • May 18th, 2015
May 18th, 2015 •
1, 2, 3, 1
1Department of Materials Science and Engineering, University of Sheffield, 2Department of Oncology and Insigneo Institute for in silico Medicine, University of Sheffield, 3Department of Histopathology, Sheffield Teaching Hospitals NHS Foundation Trust

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Dette manuskriptet beskriver produksjon, karakterisering og potensielle anvendelser av en vev konstruert 3D esophageal konstruere forberedt fra normal primære humane esophageal fibroblast og squamous epitelceller seeded innenfor en de-cellularized svin stillaset. Resultatene viser dannelsen av et modent stratifisert epitel lik den normale humane spiserøret.

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Bioteknologi spiserør epitel tissue engineering 3D-konstruksjon spiserørskreft Barretts Metaplasi
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