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JoVE Journal Bioengineering
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A Method for Determination and Simulation of Permeability and Diffusion in a 3D Tissue Model in a Membrane Insert System for Multi-well Plates

Article DOI: 10.3791/56412-v • 10:33 min • February 23rd, 2018
February 23rd, 2018 •
1, 1, 1, 1, 2, 2, 3, 1
1Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 2Institute of Biotechnology, Department Medical Biotechnology, Technische Universität Berlin, 3TissUse GmbH

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A method for determination of permeability in a membrane insert system for multi-well plates and in silico parameter optimization for the calculation of diffusion coefficients using simulation are presented.

Tags

Permeability Diffusion 3D Tissue Model Membrane Insert System Multi-well Plates Protocol Skin Tissue Engineering Pharmaceutical Application Cosmetic Application Quality Factors Measurement Technique Organ On A Chip Devices Agarose Gel Collagen Cell Model Permeability Assay Primary Fibroblasts Complete Medium
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