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High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

Article DOI: 10.3791/3103-v • 09:18 min • July 29th, 2011
July 29th, 2011 •
1, 1, 1, 1, 1, 1, 1, 1, 1
1Center for Arrhythmia Research. Internal Medicine, University of Michigan

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This report provides a detailed description of the methodology and results of simultaneous endocardial and epicardial optical mapping of electrical excitation in the intact left atrium of a Langendorff-perfused sheep heart during stretch-induced atrial fibrillation.

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High-resolution Endocardial Epicardial Optical Mapping Sheep Model Stretch-induced Atrial Fibrillation AF Cardiac Arrhythmia Morbidity Mortality Intra-atrial Pressure Dilatation Animal Models Stretch AF Dynamics Visualization Electrical Waves Spatial Resolution Temporal Resolution Conventional Electrical Mapping Human Electrophysiological Studies Intra-atrial Electrodes Optical Mapping Wide-field Characterization Sub-millimeter Spatial Resolution Fibrillatory Activity Rotors Ventricles Atria Time-domain Analysis Frequency-domain Analysis
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