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Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces

Article DOI: 10.3791/51723-v • 08:50 min • September 26th, 2014
September 26th, 2014 •
1, 1, 1, 1, 2, 2, 3, 2, 1
1MRC Centre for Regenerative Medicine, University of Edinburgh, 2School of Chemistry, University of Edinburgh, 3MRC Centre for Inflammation Research, University of Edinburgh

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Summary
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This article will focus on developing polymer coated surfaces for long-term, stable culture of stem cell derived human hepatocytes.

Tags

Cell Biology Differentiated Cell Phenotype Biological Matrices Primary Hepatocytes Pluripotent Stem Cells Synthetic Surfaces Synthetic Polymer Coating Polymers Biomaterials Mechanical Properties Physical Properties Chemical Properties Batch-to-batch Consistency High-throughput Screening Pharmaceutical Testing Industry Cellular-based Therapy Polyurethanes
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