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Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
JoVE Journal
Biotechnik
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JoVE Journal Biotechnik
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
DOI:

10:35 min

February 25, 2020

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Kapitel

  • 00:05Introduction
  • 01:26Dermal Graft Preparation
  • 03:13Muscle Graft Preparation
  • 04:44Common Peroneal (CP) Nerve Isolation and Preparation
  • 06:26Composite Regenerative Peripheral Nerve Interface (C-RPNI) Construct Fabrication
  • 08:20Results: Representative C-RPNI Characterization and Functional Analysis
  • 09:46Conclusion

Summary

Automatische Übersetzung

The following manuscript describes a novel method for developing a biologic, closed loop neural feedback system termed the composite regenerative peripheral nerve interface (C-RPNI). This construct has the ability to integrate with peripheral nerves to amplify efferent motor signals while simultaneously providing afferent sensory feedback.

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