Waiting
Login-Verarbeitung ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / A Benchtop Approach to the Location Specific…
JoVE Journal
Neuroscience

Ein Abonnement für JoVE ist erforderlich, um diesen Inhalt ansehen zu können.

JoVE Journal Neuroscience
A Benchtop Approach to the Location Specific Blood Brain Barrier Opening using Focused Ultrasound in a Rat Model
Why Quantification Matters: Characterization of Phenotypes at the Drosophila Larval Neuromuscular Junction
Journal (Neuroscience)
Why Quantification Matters: Characterization of Phenotypes at the Drosophila Larval Neuromuscular Junction
Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays
Journal (Neuroscience)
Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays
 

A Benchtop Approach to the Location Specific Blood Brain Barrier Opening using Focused Ultrasound in a Rat Model

Article DOI: 10.3791/61113-v • 09:17 min • June 13th, 2020
June 13th, 2020 •
1, 1, 2, 1
1Department of Radiology, University of Alabama at Birmingham, 2Department of Neurobiology, University of Alabama at Birmingham

Kapitel

Summary
Automatic Translation

Focused ultrasound with microbubble agents can open the blood brain barrier focally and transiently. This technique has been used to deliver a wide range of agents across the blood brain barrier. This article provides a detailed protocol for the localized delivery to the rodent brain with or without MRI guidance.

Tags

Benchtop Blood-brain Barrier Focused Ultrasound Rat Model Micro-bubbles Non-invasive Delivery Catheter Plug Saline Tail Vein Catheter Evans Blue Dye Gadobutrol MRI Contrast Experimental Agent Sheath Lab Tape Anesthesia Line Stereotactic Frame MRI Bed T2 Weighted Images
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter