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Um modelo murino da doença da encefalite viral aguda induzida pelo vírus da dengue

Article DOI: 10.3791/59132-v • 04:23 min • April 28th, 2019
April 28th, 2019 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3
1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 2Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, 3Center of Infectious Disease and Signaling Research, National Cheng Kung University

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Aqui, nós apresentamos um protocolo para criar um modelo murino imuno-competente do ICR (Instituto do cancer da pesquisa) da infecção do sistema nervoso central para indicar o desenvolvimento da neuropatia. A monitoração de desordens encefalalitic virais agudas por contagens idênticas da doença podia ser executada mostrando a neuropatia vírus-induzida dengue in vivo.

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Imunologia e infecção murine vírus da dengue encefalite neurotoxicidade injeção intracerebral injeção intraperitoneal ratos amamentando
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