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JoVE Journal
Biochemistry

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JoVE Journal Biochemistry
Transplantation of Neonatal Mouse Cardiac Macrophages into Adult Mice
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Transplantation of Neonatal Mouse Cardiac Macrophages into Adult Mice

Article DOI: 10.3791/62108-v • 06:10 min • March 20th, 2021
March 20th, 2021 •
1, 1, 1, 1, 1, 1,2
1Fuwai Hospital & Chinese Academy of Medical Sciences, State Key Laboratory of Cardiovascular Disease, Cardiovascular Institute, National Center for Cardiovascular Diseases, Peking Union Medical College, 2National Health Commission Key Laboratory of Cardiovascular Regenerative Medicine, Fuwai Central-China Hospital, Central-China Subcenter of National Center for Cardiovascular Diseases

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résumé
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We provide a protocol for neonatal cardiac macrophage separation and transplantation into an adult mouse heart, which could be a promising way to promote cardiac repair.

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Neonatal Mouse Cardiac Macrophages Transplantation Adult Mice Cardiac Repair Heart Regeneration Operating Platform Anesthetized Mouse Supine Position Stereoscope Disinfect Chest Cavity Intercostal Muscles Microsurgical Scissors Exteriorized Heart Ventricular Apex Tissue Left Ventricular Chamber Prolene Sutures
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