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JoVE Journal Behavior
Bruke en murine modell av psykososialt stress i svangerskapet som et oversettelsesrelevant paradigme for psykiatriske lidelser hos mødre og spedbarn
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Bruke en murine modell av psykososialt stress i svangerskapet som et oversettelsesrelevant paradigme for psykiatriske lidelser hos mødre og spedbarn

Article DOI: 10.3791/62464-v • 06:39 min • June 13th, 2021
June 13th, 2021 •
1,2,3, 4, 1,2,3
1Molecular Developmental Biology Program, Cincinnati Children’s Hospital Medical Center, 2Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, 3Department of Pediatrics, University of Cincinnati College of Medicine, 4Division of Veterinary Services, Cincinnati Children’s Hospital Medical Center

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Det kroniske psykososiale stressparadigmet (CGS) bruker klinisk relevante stressfaktorer under graviditet hos mus for å modellere psykiatriske lidelser hos mødre og spedbarn. Her tilbyr vi en trinnvis prosedyre for å bruke CGS-paradigmet og nedstrømsvurderinger for å validere denne modellen.

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Atferd utgave 172 kronisk psykososialt stress graviditet atferd nevroendokrine funksjon perinatal stemning og angstlidelser
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