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Ovarian Cancer Patient-Derived Organoid Models for Pre-Clinical Drug Testing

Article DOI: 10.3791/65068-v • 05:35 min • September 15th, 2023
September 15th, 2023 •
1, 1, 1, 1, 1, 1
1Washington University of Medicine in St. Louis

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We present a protocol that can be used to conduct therapeutic drug testing with patient-derived ovarian cancer organoids.

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Ovarian Cancer Patient-derived Organoid Models Pre-clinical Drug Testing Gynecologic Cancer Drug Treatments Healthcare Patient Outcomes Organoids In-vitro Three-dimensional Multicellular Miniature Organs PDO Models Drug Screening Two-dimensional Cell Culture Models Patient-derived Xenografts Tumor Microenvironment Genetic Background Ovarian Cancer Tissue Ascites Luminescence-based Adenosine Triphosphate (ATP) Assay Viability Growth Rate Drug Sensitivity
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