Tokyo Animal Eye Clinic 1 article published in JoVE Medicine A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion Deokho Lee*1,2, Yukihiro Miwa*1,2,3, Heonuk Jeong1,2, Shin-ichi Ikeda1,2, Yusaku Katada1,2, Kazuo Tsubota1,2,4, Toshihide Kurihara1,2 1Laboratory of Photobiology, Keio University School of Medicine, 2Department of Ophthalmology, Keio University School of Medicine, 3Animal eye care, Tokyo Animal Eye Clinic, 4Tsubota Laboratory, Inc. Here, we describe a mouse model of retinal ischemia by transient bilateral common carotid artery occlusion using simple sutures and a clamp. This model can be useful for understanding the pathological mechanisms of retinal ischemia caused by cardiovascular abnormalities.
