2 articles published in JoVE
Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent Sungmin Kang1, Michael Bruyns-Haylett2, Yurie Hayashi1, Ying Zheng1 1School of Biological Sciences, Whiteknights, University of Reading, 2Department of Bioengineering, Imperial College This protocol describes a simple method for concurrent recording of co-localized electroencephalography (EEG) and multi-laminar local field potential in an anesthetized rat. A burr hole drilled in the skull for the insertion of a microelectrode is shown to produce negligible distortion of the EEG signal.
Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy Peter Heath1, Sandrine Paule Claus2 1School of Chemistry, Food and Pharmacy, The University of Reading, 2Department of Nutritional Sciences, The University of Reading A progressive colonization procedure is described to further assess its impact on the host hepatic metabolism. Colonization is monitored non invasively by evaluating the urinary excretion of microbial co-metabolites by NMR-based metabolic profiling while hepatic metabolism is assessed by High Resolution Magic Angle Spinning (HR MAS) NMR profiling of intact biopsy.