Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Marion Gilormini; Anne-Sophie Wozny; Priscillia Battiston-Montagne; Dominique Ardail; Gersende Alphonse; Claire Rodriguez-Lafrasse

doi:10.3791/53958

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Isolamento e caratterizzazione di un testa e del collo a cellule squamose Carcinoma sottopopolazione Avere Stem Cell Caratteristiche

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

JoVE Journal
Medicina

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JoVE Journal Medicina

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Isolamento e caratterizzazione di un testa e del collo a cellule squamose Carcinoma sottopopolazione Avere Stem Cell Caratteristiche

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8,536 Views

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11:28 min

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May 11, 2016

DOI:

10.3791/53958-v

DOI:

10.3791/53958-v

•

11:28 min

May 11, 2016

•

8501 Views

Marion Gilormini¹, Anne-Sophie Wozny^1,2, Priscillia Battiston-Montagne¹, Dominique Ardail^1,2, Gersende Alphonse^1,2, Claire Rodriguez-Lafrasse^1,2

¹UCBL1, UMR/CNRS 5822, Laboratoire de Radiobiologie Cellulaire Moléculaire,Université de Lyon ²Hospices-Civils-de-Lyon, Centre Hospitalier Lyon-Sud

Summary

Understanding the role of cancer stem-like cells in tumor recurrence and resistance to therapies has become a topic of great interest in the last decade. This article describes the isolation and characterization of the sub-population of cancer stem-like cells from head and neck squamous carcinoma cell lines (HNSCC).