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Cancer Research

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A Time-lapse, Label-free, Quantitative Phase Imaging Study of Dormant and Active Human Cancer Cells

Article DOI: 10.3791/57035-v • 12:48 min • February 16th, 2018
February 16th, 2018 •
*1,2, *1,2, 1,2
1Vascular Biology Program, Boston Children's Hospital, 2Department of Surgery, Harvard Medical School and Boston Children's Hospital
* These authors contributed equally

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Dormant and active cancer cell phenotypes were characterized using quantitative phase imaging. Cell proliferation, migration, and morphology assays were integrated and analyzed in one simple method.

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Time-lapse Label-free Quantitative Phase Imaging Dormant Cancer Cells Active Cancer Cells Angiogenic Phenotype Non-angiogenic Phenotype Human Osteosarcoma Cells Cell Morphology Cell Proliferation Cell Motility Tumor Dormancy Endogenic Switch Multicellular Parameters Cell Area Cell Thickness Cell Volume Proliferation Rate Doubling Time Motility Speed Migration Speed Thawing Process Culture Medium
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