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Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

Article DOI: 10.3791/2148-v • 14:55 min • April 18th, 2011
April 18th, 2011 •
1,2, 1, 1, 1,3
1Sensory Motor Performance Program, Rehabilitation Institute of Chicago, 2Department of Kinesiology and Nutrition, University of Illinois at Chicago, 3Department of Physical Therapy, University of Illinois at Chicago

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This video demonstrates modulation of reflex activity, volitional strength and ambulation through clinical and quantitative assessments in individuals with motor incomplete SCI as a result of acute oral administration of a serotonin reuptake inhibitor (SSRI).

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Pharmacologically Induced Alterations Motor Function Human Incomplete SCI Spinal Cord Injury Volitional Motor Control Recovery From SCI Long Term Rehabilitation Walking Ability Motor Incomplete SCI Residual Descending Pathways Motor Impairments Weakness Abnormal Involuntary Reflex Activity Spasticity Spasms Walking Recovery Abnormal Motor Reflexes Functional Benefits Pharmacological Interventions Physical Interventions Empirical Data Neuromodulatory Agents Monoamines Serotonin (5HT) Norepinephrine (NE) Walking Behaviors Animal Models Of SCI
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