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Measuring Changes in Tactile Sensitivity in the Hind Paw of Mice Using an Electronic von Frey Apparatus

Article DOI: 10.3791/51212-v • 07:49 min • December 19th, 2013
December 19th, 2013 •
1, 1, 1, 1
1Biology Department, Macalester College

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Electronic von Frey measurements are an effective and improved alternative to classical von Frey filaments, as they allow rapid and precise measurement of changes in rodent mechanical withdrawal thresholds to continuously applied pressure stimuli before and after an inflammatory event.

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Measuring Changes Tactile Sensitivity Hind Paw Mice Electronic Von Frey Apparatus Inflammation-induced Changes Thresholds Pain Perception Rodents Withdrawal Thresholds Baseline Measurements Drug-induced Inflammation Venom-induced Inflammation Injury-induced Inflammation Allergen-induced Inflammation Evoked Inflammation Precise Assessment Mouse Hind Paw Withdrawal Thresholds Filament Sizes Classical Von Frey Measurements Ease And Rapidity Of Measurements Tactile Sensitivity Outcomes Rapid-onset Inflammatory Pain Models Neuropathic Pain Models Multiple Measurements Short Time Period Experimental Measurements Individual Rodent Subjects Internal Control Exclusion Criteria Standardize Baseline Responses Experimental Groups
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