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Journal / Bioengineering / रासायनिक Epigenetic संशोधक के साथ सेलुलर मशीनरी…
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Bioengineering

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JoVE Journal Bioengineering
रासायनिक Epigenetic संशोधक के साथ सेलुलर मशीनरी को पुनः निर्देशित करके जीन प्रतिलेखन का दमन
Assessing Collagen and Elastin Pressure-dependent Microarchitectures in Live, Human Resistance Arteries by Label-free Fluorescence Microscopy
Journal (Bioengineering)
Assessing Collagen and Elastin Pressure-dependent Microarchitectures in Live, Human Resistance Arteries by Label-free Fluorescence Microscopy
Electrospinning Growth Factor Releasing Microspheres into Fibrous Scaffolds
Journal (Bioengineering)
Electrospinning Growth Factor Releasing Microspheres into Fibrous Scaffolds
 
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रासायनिक Epigenetic संशोधक के साथ सेलुलर मशीनरी को पुनः निर्देशित करके जीन प्रतिलेखन का दमन

Article DOI: 10.3791/58222-v • 10:28 min • September 20th, 2018
September 20th, 2018 •
1, 2, 3, 3, 4
1Chemical Biology and Medicinal Chemistry, Center for Integrative Chemical Biology and Drug Discovery, Curriculum in Genetics and Molecular Biology, University of North Carolina, 2College of Arts and Sciences, Chemical Biology and Medicinal Chemistry, Center for Integrative Chemical Biology and Drug Discovery, University of North Carolina, 3Chemical Biology and Drug Discovery, Pharmacological Sciences and Oncological Sciences, Icahn School of Medicine at Mount Sinai, 4Chemical Biology and Medicinal Chemistry, Center for Integrative Chemical Biology and Drug Discovery, Curriculum in Genetics and Molecular Biology, Lineberger Comprehensive Cancer Center, University of North Carolina

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क्रोमेटिन पर्यावरण का विनियमन उचित जीन अभिव्यक्ति के लिए आवश्यक प्रक्रिया है । यहां, हम एक जीन विशिष्ट और प्रतिवर्ती तरीके से क्रोमेटिन-संशोधित मशीनरी की भर्ती के माध्यम से जीन अभिव्यक्ति को नियंत्रित करने के लिए एक विधि का वर्णन ।

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जैव अभियांत्रिकी निर्गम १३९ रासायनिक जीव विज्ञान bifunctional अणुओं रासायनिक प्रेरित निकटता क्रोमेटिन विनियमन जीन दमन हिस्टोन deacetylase epigenetics रासायनिक epigenetic संशोधक CEMs
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