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Biology

量化混合使用磁共振成像

Published: January 25, 2012 doi: 10.3791/3493

Summary

磁共振成像(MRI)提供了强大的工具来评估在操作过程中的工艺设备的有效性。我们讨论了使用的MRI可视化静态混合器混合。该应用程序相关的个人护理产品,但可以适用于广泛的食品,化工,生物量和生物体液。

Abstract

Protocol

Discussion

Disclosures

作者M. McCarthy是看点成像,作者属浆果有限公司和W. Hartt宝洁,公司的员工顾问

Acknowledgments

作者想感谢方面的研究中所使用的脉冲序列成像(工业区Hevel Modi'in,Shoham,以色列)。这项工作是部分资金从过程分析化学中心的华盛顿大学(西雅图,华盛顿州,美国),以及实物捐助和宝洁公司的财务支持奖。

Materials

Name Company Catalog Number Comments
Aspect 1T imaging spectrometer Aspect Imaging
AR-G2 rheometer TA Instruments
Seepex metering pumps Seepex GmbH
Carbopol The Lubrizol corporation, (Wickliffe, OH)
Manganese Chloride 1M Solution Fisher Scientific

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References

  1. Callaghan, P. T. Principles of Nuclear Magnetic Resonance Microscopy. , Clarendon Press. Oxford. (1991).
  2. McCarthy, M. J. Magnetic Resonance Imaging in Foods. , Chapman & Hall. New York, NY. (1994).
  3. Mixer. US patent. Sluijters, R. , 3182965 (1965).
  4. van der Hoeven, J. C., Wimberger-Friedl, R., Meijer, H. E. H. Homogeneity of multilayers produced with a static mixer. Polymer. Eng. Sci. 41, 32-42 (2001).
  5. Steffe, J. F. Rheological Methods in Food Process Engineering. , 2nd Ed, Freeman Press. East Lansing, MI. (1996).
  6. Lee, Y., McCarthy, M. J., McCarthy, K. L. Extent of mixing in a two-component batch system measured using MRI. J. Food. Eng. 50, 167-174 (2001).
  7. McCarthy, K. L., Lee, Y., Green, J., McCarthy, M. J. Magnetic resonance imaging as a sensor system for multiphase mixing. Applied Magnetic Resonance. 22, 213-222 (2002).
  8. Choi, Y. J., McCarthy, M. J., McCarthy, K. L. MRI for process analysis: Co-rotating twin screw extruder. Journal of Process Analytical Chemistry. 9, 72-84 (2004).
  9. Rees, A. C., Davidson, J. F., Dennis, J. S., Fennell, P. S., Gladden, L. F., Hayhurst, A. N., Mantle, M. D., Muller, C. R., Sederman, A. J. The nature of the flow just above the perforated plate distributor of a gas-fluidised bed, as imaged using magnetic resonance. Chemical Eng. Sci. 61, 6002-6015 (2006).
  10. Stevenson, R., Harrison, S. T. L., Mantle, M. D., Sederman, A. J., Moraczewski, T. L., Johns, M. L. Analysis of partial suspension in stirred mixing cells using both MRI and ERT. Chem. Eng. Sci. 65, 1385-1393 (2010).
  11. Benson, M. J., Elkins, C. J., Mobley, P. D., Alley, M. T., Eaton, J. K. Three-dimensional concentration field measurements in a mixing layer using magnetic resonance imaging. Exp. Fluids. 49, 43-55 (2010).

Tags

生物物理学,59期,磁共振成像,MRI,搅拌,流变,静态混合器,分裂和重组组合
量化混合使用磁共振成像
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Cite this Article

Tozzi, E. J., McCarthy, K. L.,More

Tozzi, E. J., McCarthy, K. L., Bacca, L. A., Hartt, W. H., McCarthy, M. J. Quantifying Mixing using Magnetic Resonance Imaging. J. Vis. Exp. (59), e3493, doi:10.3791/3493 (2012).

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