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Mikrofluidisk nekrotiserande enterokolit-på-en-chip-modell för att studera NEC-patofysiologi

A Necrotizing Enterocolitis Model for Mechanistic Studies and Drug Discovery

Article DOI: 10.3791/200450-v • 06:10 min • July 28th, 2023
July 28th, 2023 •
1, 1, 1, 2, 3, 1, 1, 1, 1
1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, 2University of Nebraska College of Medicine, 3Department of Surgery, Washington University School of Medicine

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Mikrofluidisk modell nekrotiserande enterokolit humana neonatala tarmenteroider dysbiotisk mikrobiom komplex patogenes tarmtrånga korsningar tarmbarriärpermeabilitet epitelcellsdöd mikrobiell dysbios dysreglerad inflammation djurmodeller cellinjer tarmorganoider in vitro-modell mikrofluidisk teknologi NEC-on-a-chip prematura nyfödda humana endotelceller läkemedelstestning
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