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Neuroscience

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JoVE Journal Neuroscience

Constructing the 3D Human-Stem-Cell-Derived In Vitro Blood Brain Barrier (Video) | JoVE

Exploring Non-Motor Symptoms in Parkinson's Disease (Video) | JoVE

Journal (Neuroscience)

Exploring Non-Motor Symptoms in Parkinson's Disease (Video) | JoVE

A Single-fly Assay for Foraging Behavior in Drosophila

Journal (Neuroscience)

A Single-fly Assay for Foraging Behavior in Drosophila

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Constructing the 3D Human-Stem-Cell-Derived In Vitro Blood Brain Barrier (Video) | JoVE

A 3D Blood-Brain Barrier Model Derived from Human Pluripotent Stem-Cells

Article DOI: 10.3791/200668-v • 02:08 min • October 20th, 2023

October 20th, 2023 •

Camille Goldman*^1,2,3,4,5, Natalie Suhy*^1,2,3,4,5, Jessica E. Schwarz^1,2,3,4,5, Emily Ruth Sartori^1,2,3,4,5, Rikki B. Rooklin^1,2,3,4,5, Braxton R. Schuldt^1,2,3,4,5, Louise A. Mesentier-Louro^1,2,3,4,5, Joel W. Blanchard^1,2,3,4,5

¹Icahn School of Medicine at Mount Sinai, ²Black Family Stem Cell Institute at Mount Sinai, ³Ronald M. Loeb Center for Alzheimer’s Disease at Mount Sinai, ⁴Friedman Brain Institute at Mount Sinai, ⁵Nash Family Department of Neuroscience at Mount Sinai

* These authors contributed equally

Tags

Blut-Hirn-Schranke ZNS neurologische Erkrankungen therapeutische Medikamentenverabreichung BHS-Funktion zerebrale Amyloid-Angiopathie Alzheimer-Krankheit Neurodegeneration menschliche pluripotente Stammzellen Endothelzellen Perizyten Astrozyten 3D-Matrix IBBB Amyloid-Ablagerung zerebrovaskuläre Erkrankung genetische Faktoren Umweltfaktoren Arzneimittelscreening medizinisches Targeting

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