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Journal / Immunology and Infection / Transnuclear Muizen met vooraf gedefinieerde…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Transnuclear Muizen met vooraf gedefinieerde T-cel-receptor Bijzonderheden tegen Toxoplasma gondii Verkregen via SCNT
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Journal (Immunology and Infection)
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Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
Journal (Immunology and Infection)
Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
 
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Transnuclear Muizen met vooraf gedefinieerde T-cel-receptor Bijzonderheden tegen Toxoplasma gondii Verkregen via SCNT

Article DOI: 10.3791/2168-v • 13:37 min • September 30th, 2010
September 30th, 2010 •
1, 1, 1,2, 1, 1,3, 1,3
1Whitehead Institute for Biomedical Research, 2Departments of Microbiology and Biological Sciences, National University of Singapore, 3Department of Biology, Massachusetts Institute of Technology

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We zien hier dat epigenetische herprogrammering via Somatic Cell Nuclear Transfer (SCNT) kan worden gebruikt als een instrument om muismodellen te genereren met een vooraf bepaalde T-cel receptor (TCR) specifieke kenmerken. Deze transnuclear muizen drukken de overeenkomstige TCR uit hun endogene locus onder de controle van de endogene promotor.

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Developmental Biology SCNT immunologie TCR BCR muismodel transnuclear
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