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Ex vivo Mimetismo de normal e anormal Hematopoese Humanos

Article DOI: 10.3791/3654-v • 11:50 min • April 10th, 2012
April 10th, 2012 •
1, 1, 1, 1, 1, 1, 2
1Department of Chemical Engineering and Chemical Technology, South Kensington campus, Imperial College London, 2Department of Hematology, Northwick Park & St. Mark's campus, Imperial College London

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Um sistema de cultura de 3D para a hematopoiese é descrito usando sangue do cordão umbilical humano e células de medula óssea leucémicas. O método baseia-se na utilização de um poliuretano poroso sintético andaime revestido com proteínas da matriz extracelular. Este andaime é adaptável para acomodar uma grande variedade de células.

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Emissão Bioengineering 62 a cultura tridimensional a hematopoiese a leucemia o sangue do cordão
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