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JoVE Journal
Neuroscience

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JoVE Journal Neuroscience
Feeder-free Derivation of Neural Crest Progenitor Cells from Human Pluripotent Stem Cells
 

Feeder-free Derivation of Neural Crest Progenitor Cells from Human Pluripotent Stem Cells

Article doi: 10.3791/51609
May 22nd, 2014 •
1, 2, 1, 1
1Developmental Biology, Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, 2St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University

Summary
Automatic Translation
May 22nd, 2014

Neural crest (NC) cells derived from human pluripotent stem cells (hPSC) have great potential for modeling human development and disease and for cell replacement therapies. Here, a feeder-free adaptation of the currently widely used in vitro differentiation protocol for the derivation of NC cells from hPSCs is presented.
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