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Amid-Kupplung für die Synthese von Bispyridin basierten Liganden und ihre Komplexierung Platinum als zweikernige Antikrebsmittel
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Amid-Kupplung für die Synthese von Bispyridin basierten Liganden und ihre Komplexierung Platinum als zweikernige Antikrebsmittel

Article DOI: 10.3791/51740-v • 07:20 min • May 28th, 2014
May 28th, 2014 •
1, 2, 3, 4, 1
1Faculty of Pharmacy, The University of Sydney, 2School of Science and Health, University of Western Sydney, 3Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, 4Nature Publishing Group

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Dieses Protokoll beschreibt die Verwendung von Amid-Kupplungen von Isonicotinsäure und Diaminoalkane zu Brückenliganden, die zur Verwendung in der Synthese von mehrkernigen Platinkomplexe, welche Aspekte der Antikrebs-Arzneimittel und BBR3464 picoplatin kombinieren bilden.

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Chemie Heft 87 BBR3464 picoplatin Bispyridin Amid-Kopplung anorganische Synthese Krebs
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