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JoVE Journal
Behavior

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Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker
 

Disrupting Reconsolidation of Fear Memory in Humans by a Noradrenergic β-Blocker

Article doi: 10.3791/52151
December 18th, 2014 Usage Statistics

Summary December 18th, 2014

Disrupting reconsolidation is a promising approach to dampen the behavioral expression of fear memory in patients with anxiety disorders or posttraumatic stress disorder. In a series of human fear conditioning studies we showed that disrupting reconsolidation by the noradrenergic β-blocker propranolol is very effective in erasing conditioned fear responding.

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